Search Results - "Khachaturian, Z"

Report of the task force on designing clinical trials in early (predementia) AD by AISEN, P. S, ANDRIEU, S, HENDRIX, S. B, GRUNDMAN, M, SCHNEIDER, L. S, SCHINDLER, R. J, SALMON, E, POTTER, W. Z, THOMAS, R. G, SALMON, D, DONOHUE, M, BEDNAR, M. M, SAMPAIO, C, TOUCHON, J, VELLAS, B, CARRILLO, M, KHACHATURIAN, Z. S, DUBOIS, B, FELDMAN, H. H, PETERSEN, Rc, SIEMERS, E, DOODY, R. S

“…A large number of promising candidate disease-modifying treatments for Alzheimer disease (AD) continue to advance into phase II and phase III testing. However,…”
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Revisiting the Cholinergic Hypothesis in Alzheimer’s Disease: Emerging Evidence from Translational and Clinical Research by Hampel, Harald, Mesulam, M.-M., Cuello, A. C., Khachaturian, A. S., Vergallo, A., Farlow, M. R., Snyder, P. J., Giacobini, E., Khachaturian, Z. S.

“…Scientific evidence collected over the past 4 decades suggests that a loss of cholinergic innervation in the cerebral cortex of patients with Alzheimer’s…”
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Calcium hypothesis of Alzheimer's disease and brain aging by Khachaturian, Z S

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Consensus Recommendations for the Postmortem Diagnosis of Alzheimer’s Disease by KHACHATURIAN, Zaven, PHELPS, Creighton, TROJANOWSKI, John Q

“…This report summarizes the consensus recommendations of a panel of neuropathologists from the United States and Europe to improve the postmortem diagnostic…”
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Diagnosis and Treatment of Alzheimer Disease and Related Disorders: Consensus Statement of the American Association for Geriatric Psychiatry, the Alzheimer's Association, and the American Geriatrics Society by Small, Gary W, Rabins, Peter V, Barry, Patricia P, Buckholtz, Neil S, DeKosky, Steven T, Ferris, Steven H, Finkel, Sanford I, Gwyther, Lisa P, Khachaturian, Zaven S, Lebowitz, Barry D, McRae, Thomas D, Morris, John C, Oakley, Frances, Schneider, Lon S, Streim, Joel E, Sunderland, Trey, Teri, Linda A, Tune, Larry E

“…Objective.—A consensus conference on the diagnosis and treatment of Alzheimer disease (AD) and related disorders was organized by the American Association for…”
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Alzheimer's disease: etiologies, pathophysiology, cognitive reserve, and treatment opportunities by Cummings, J L, Vinters, H V, Cole, G M, Khachaturian, Z S

“…Alzheimer's disease (AD) can be diagnosed with a considerable degree of accuracy. In some centers, clinical diagnosis predicts the autopsy diagnosis with 90%…”
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Calcium, membranes, aging, and Alzheimer's disease. Introduction and overview by Khachaturian, Z S

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Editorial: The 'Aducanumab Story': Will the Last Chapter Spell the End of the 'Amyloid Hypothesis' or Mark a New Beginning? by Khachaturian, Z S

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Perspective on Failed Trial Re: Efficacy of Nutritional Supplement to Prevent Cognitive Decline by Khachaturian, Z S

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Neurobiology of aging: Alzheimer’s clinical review series: Bridging bench to bedside: clinical problems in search of basic solution by Khachaturian, Zaven S

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Hypothesis on the regulation of cytosol calcium concentration and the aging brain by Khachaturian, Z S

“…This commentary proposes that neurobiology of aging must look beyond the issue of age related changes in calcium concentrations within the cytosol. The more…”
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An overview of Alzheimer's disease research by Khachaturian, Z S

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Future research directions by Khachaturian, Z

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Prospects of Developing Interventions to Prevent Alzheimer's Disease by Khachaturian, Zaven S.

“…Based largely on recommendations of scientists from around the world, it is possible to discover treatments designed to maintain independent functioning of…”
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Potential use of nerve growth factor to treat Alzheimer's disease by Phelps, C H, Gage, F H, Growdon, J H, Hefti, F, Harbaugh, R, Johnston, M V, Khachaturian, Z S, Mobley, W C, Price, D L, Raskind, M

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Alzheimer disease: where are we now? Where are we going? by Khachaturian, Z S, Radebaugh, T S

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Amplifying Efficiency and Accuracy in Dementia Drug Development by Lerch, O., Levine, S. Z., Sivakumaran, S., Lutz, M. W., Chiba-Falek, O., Mazer, N., Bairu, M., Haraldsen, I. R. J. Hebold, Rossini, P. M., Snyder, P. J., Bouteiller, J., Khachaturian, Z. S., Khachaturian, Ara S.

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Editorial: Amplifying Efficiency and Accuracy in Dementia Drug Development by Lerch, O, Levine, S Z, Sivakumaran, S, Lutz, M W, Chiba-Falek, O, Mazer, N, Bairu, M, Hebold Haraldsen, I R J, Rossini, P M, Snyder, P J, Bouteiller, J, Khachaturian, Z S, Khachaturian, A S

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Overview of basic research on Alzheimer disease: implications for cognition by Khachaturian, Z S

“…During the past 12 years, research on the etiology of Alzheimer disease (AD) has made dramatic advances. Although we still do not have a clear picture of what…”
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Progress of Research on Alzheimer's Disease: Research Opportunities for Behavioral Scientists by Khachaturian, Zaven S

“…Presents recommendations for research needs in the behavioral sciences to improve the diagnosis of Alzheimer's disease (AD). Among the suggestions made are…”
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