Search Results - "Kfir, Nir"
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Degradation of Bcl-2 by XIAP and ARTS Promotes Apoptosis
Published in Cell reports (Cambridge) (10-10-2017)“…We describe a mechanism by which the anti-apoptotic B cell lymphoma 2 (Bcl-2) protein is downregulated to induce apoptosis. ARTS (Sept4_i2) is a tumor…”
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Assembly and annotation of the Gossypium barbadense L. 'Pima-S6' genome raise questions about the chromosome structure and gene content of Gossypium barbadense genomes
Published in BMC genomics (10-01-2023)“…Gossypium barbadense L. Pima cotton is known for its resistance to Fusarium wilt and for producing fibers of superior quality highly prized in the textile…”
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3
SF3B1 association with chromatin determines splicing outcomes
Published in Cell reports (Cambridge) (28-04-2015)“…Much remains unknown concerning the mechanism by which the splicing machinery pinpoints short exons within intronic sequences and how splicing factors are…”
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4
A small-molecule ARTS mimetic promotes apoptosis through degradation of both XIAP and Bcl-2
Published in Cell death & disease (25-06-2020)“…Many human cancers over-express B cell lymphoma 2 (Bcl-2) or X-linked inhibitor of apoptosis (IAP) proteins to evade cell death. The pro-apoptotic ARTS…”
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5
High-quality chromosome-scale genomes facilitate effective identification of large structural variations in hot and sweet peppers
Published in Horticulture research (2022)“…Abstract Pepper (Capsicum annuum) is an important vegetable crop that has been subjected to intensive breeding, resulting in limited genetic diversity,…”
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Alu exonization events reveal features required for precise recognition of exons by the splicing machinery
Published in PLoS computational biology (01-03-2009)“…Despite decades of research, the question of how the mRNA splicing machinery precisely identifies short exonic islands within the vast intronic oceans remains…”
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7
Overlapping splicing regulatory motifs--combinatorial effects on splicing
Published in Nucleic acids research (01-06-2010)“…Regulation of splicing in eukaryotes occurs through the coordinated action of multiple splicing factors. Exons and introns contain numerous putative binding…”
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Alu Exonization Events Reveal Features Required for Precise Recognition of Exons by the Splicing Machinery: e1000300
Published in PLoS computational biology (01-03-2009)“…Despite decades of research, the question of how the mRNA splicing machinery precisely identifies short exonic islands within the vast intronic oceans remains…”
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