Search Results - "Keyser, M."

Influence of discard mineral matter on slag―liquid formation and ash melting properties of coal ― A FACTSAGE™ simulation study by VAN DYK, J. C, KEYSER, M. J

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Part two: an unblinded, parallel, randomized study to assess nicotine pharmacokinetics of four Vuse Solo ENDS flavors in smokers by Keyser, Brian M., Hong, Kyung Soo, DeLuca, Patricia, Jin, Tao, Jones, Bobbette A., Nelson, Paul, Schmidt, Eckhardt, Round, Elaine K.

“…We report the findings from a randomized, parallel study designed to evaluate nicotine pharmacokinetics (PK) following 10 min of ad libitum use of electronic…”
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Evaluating socio-economic and conservation impacts of management: A case study of time-area closures on Georges Bank by Keith, David M, Sameoto, Jessica A, Keyser, Freya M, Ward-Paige, Christine A

“…Globally, economies and marine ecosystems are increasingly dependent on sustainable fisheries management (SFM) to balance social, economic, and conservation…”
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Unexpected Expression and Function of FcεRI in Immortalized Breast Cancer Cells: A Cautionary Null Study by Ashbaugh, Alexandria M, Lyons, David O, Keyser, Carianna M, Pullen, Nicholas A

“…The high-affinity IgE receptor, FcεRI, is typically associated with type 2 effectors such as mast cells (MC). The relatively unique expression profile of FcεRI…”
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Evaluation of Cytotoxicity and Oxidative Stress of Whole Aerosol from Vuse Alto ENDS Products by Keyser, Brian M, Leverette, Robert, Wertman, John, Shutsky, Tom, McRae, Reagan, Szeliga, Ken, Makena, Patrudu, Jordan, Kristen

“…Assessment of in vitro cytotoxicity is an important component of tobacco product toxicological evaluations. However, current methods of regulatory testing…”
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Effect of coal particle size distribution on packed bed pressure drop and gas flow distribution by Keyser, M.J., Conradie, M., Coertzen, M., Van Dyk, J.C.

“…This paper focuses on the role of coal particle size distribution on pressure drop and gas flow distribution through packed coal beds. This fundamental…”
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Characterization of smoke and aerosol deliveries from combustible cigarettes, heated tobacco products and electronic nicotine delivery systems in the Vitrocell® Mammalian 6/48 exposure module by Keyser, Brian M., Leverette, Robert, Hollings, Michael, Seymour, Adam, Weidman, Randy A., Bequette, Carlton J., Jordan, Kristen

“…The rapid development associated with Next Generation Tobacco Products (NGTP) has necessitated the development of high throughput methodologies to test their…”
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NNC 55-0396 [(1S,2S)-2-(2-(N-[(3-benzimidazol-2-yl)propyl]-N-methylamino)ethyl)-6-fluoro-1,2,3,4-tetrahydro-1-isopropyl-2-naphtyl cyclopropanecarboxylate dihydrochloride]: a new selective inhibitor of T-type calcium channels by Huang, Luping, Keyser, Brian M, Tagmose, Tina M, Hansen, J Bondo, Taylor, James T, Zhuang, Hean, Zhang, Min, Ragsdale, David S, Li, Ming

“…Mibefradil is a Ca2+ channel antagonist that inhibits both T-type and high-voltage-activated Ca2+ channels. We previously showed that block of…”
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Investigation of multiple whole smoke dosimetry techniques using a VITROCELL®VC10® smoke exposure system by Keyser, Brian M., Leverette, Robert, Hollings, Michael, Seymour, Adam, Reeve, Lesley, Fields, Wanda

“…[Display omitted] •Investigation of dose-determining methods using the Vitrocell® VC10® system.•Dose assessment using Quartz Crystal Microbalances (QCM) and…”
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Cytotoxicity, oxidative stress, and inflammatory response of smokeless tobacco extracts and cytotoxicity of combustible cigarette whole smoke in a 3D oral organotypic buccal cell model by Keyser, Brian M.

“…Oral disease is frequently associated with viral and environmental exposures and oral hygiene. The use of tobacco is a risk factor in the development of oral…”
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Online Analysis of Coal on A Conveyor Belt by use of Machine Vision and Kernel Methods by Aldrich, C., Jemwa, G. T., van Dyk, J. C., Keyser, M. J., van Heerden, J. H. P.

“…The application of machine vision systems to measure particle size distributions has among other things been driven by sophisticated control systems used to…”
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In vitro toxicological evaluation of glo menthol and non-menthol heated tobacco products by Keyser, Brian M., Leverette, Robert, McRae, Reagan, Wertman, John, Shutsky, Tom, Jordan, Kristen, Szeliga, Ken, Makena, Patrudu

“…Heated tobacco products (HTPs) are non-combustible, inhaled tobacco products that generate an aerosol with fewer and lower levels of toxicants, with a…”
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PCR-based DGGE fingerprinting and identification of methanogens detected in three different types of UASB granules by Keyser, M., Witthuhn, R.C., Lamprecht, C., Coetzee, M.P.A., Britz, T.J.

“…Methane is produced by various methanogenic bacteria present in upflow anaerobic sludge blanket (UASB) bioreactors. Methane can be used to predict and improve…”
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Manipulation of the ash flow temperature and viscosity of a carbonaceous Sasol waste stream by van Dyk, J.C., Keyser, M.J., Waanders, F.B., Conradie, M.

“…In 2001 Sasol investigated the possibility to convert a Sasol-Lurgi MK III fixed bed dry bottom coal gasifier at the former Sasolburg coal-to-liquids plant to…”
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Evaluation of environmental emissions from glo heated tobacco products and combustible Cigarettes by Kanobe, Milly N., Dull, Gary M., Darnell, John, Jin, Tao, Brown, Buddy, Coffield, Jeff, Keyser, Brian M., Fearon, Ian M., Makena, Patrudu, Baxter, Sarah A., Jordan, Kristen G.

“…•glo HTPs produce lower secondhand constituents than cigarettes in indoor air.•glo HTPs reduce indoor air quality contamination more than cigarettes.•glo HTPs…”
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Inactivation of Mycobacterium avium ssp. paratuberculosis in milk by UV treatment by Donaghy, J, Keyser, M, Johnston, J, Cilliers, F.P, Gouws, P.A, Rowe, M.T

“…To determine the effect of UV radiation on the viability of two strains of Mycobacterium avium ssp. paratuberculosis (Map) inoculated into milk. Mycobacterium…”
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In vitro permeation of nicotine and tobacco specific nitrosamines from smokeless tobacco product extracts in a 3D buccal tissue model by Keyser, Brian M., Flockton, Hannah, Weidman, Randy A., Payne, Rebecca, Rowe, Jannell, Jordan, Kristen G.

“…Tobacco product use is a risk factor in the development of oral cancer, although epidemiology studies show this risk is far less with smokeless tobacco product…”
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Conceptual approaches for treatment of phosgene inhalation-induced lung injury by Holmes, Wesley W., Keyser, Brian M., Paradiso, Danielle C., Ray, Radharaman, Andres, Devon K., Benton, Betty J., Rothwell, Cristin C., Hoard-Fruchey, Heidi M., Dillman, James F., Sciuto, Alfred M., Anderson, Dana R.

“…•Describes proposed mechanisms of phosgene induced-lung injury.•Provides rational treatment strategies for phosgene inhalation injury.•Several therapeutics…”
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Development of a quantitative method for assessment of dose in in vitro evaluations using a VITROCELL® VC10® smoke exposure system by Keyser, Brian M., Leverette, Robert, Fowler, Kathy, Fields, Wanda, Hargreaves, Victoria, Reeve, Lesley, Bombick, Betsy

“…The assessment of potential cytotoxicity or genotoxicity of combustible tobacco products has historically been performed using partitioned exposures (i.e…”
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Syngas production from South African coal sources using Sasol–Lurgi gasifiers by van Dyk, J.C., Keyser, M.J., Coertzen, M.

“…Sasol has been operating the Sasol–Lurgi fixed bed coal gasification process for more than fifty years, and with ninety seven units in operation still remains…”
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