Search Results - "Keyel, Michelle"
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Intrinsic repair protects cells from pore-forming toxins by microvesicle shedding
Published in Cell death and differentiation (01-05-2017)“…Pore-forming toxins (PFTs) are used by both the immune system and by pathogens to disrupt cell membranes. Cells attempt to repair this disruption in various…”
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Spotlight on dinutuximab in the treatment of high-risk neuroblastoma: development and place in therapy
Published in Biologics (01-01-2019)“…Neuroblastoma (NB) is a pediatric cancer of the sympathetic nervous system which accounts for 8% of childhood cancers. Most NBs express high levels of the…”
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A Multi-Color Flow Cytometric Assay for Quantifying Dinutuximab Binding to Neuroblastoma Cells in Tumor, Bone Marrow, and Blood
Published in Journal of clinical medicine (27-09-2023)“…GD2, a disialoganglioside, is present on the surface of most neuroblastomas, as well as on some other cancers, such as melanoma and osteogenic sarcoma. The…”
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An Optimized Liquid Chromatography-Mass Spectrometry Method for Ganglioside Analysis in Cell Lines
Published in Cells (Basel, Switzerland) (02-10-2024)“…Gangliosides are glycosphingolipids composed of a sialylated glycan head group and a ceramide backbone. These anionic lipids form lipid rafts and play crucial…”
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