Search Results - "Keydar, Iafa"

Human Endogenous Retrovirus (HERV-K) Reverse Transcriptase as a Breast Cancer Prognostic Marker by Golan, Maya, Hizi, Amnon, Resau, James H., Yaal-Hahoshen, Neora, Reichman, Hadar, Keydar, Iafa, Tsarfaty, Ilan

“…A reverse transcriptase (RT) cDNA, designated HERV-K-T47D-RT, was isolated from a hormonally treated human breast cancer cell line. The protein product…”
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The Chemokine CCL5 as a Potential Prognostic Factor Predicting Disease Progression in Stage II Breast Cancer Patients by YAAL-HAHOSHEN, Neora, SHINA, Sima, LEIDER-TREJO, Leonor, BARNEA, Itay, SHABTAI, Esther L, AZENSHTEIN, Elina, GREENBERG, Iulia, KEYDAR, Iafa, BEN-BARUCH, Adit

“…Purpose: The aim of this study was to determine the prognostic value of the chemokine CCL5, considered as a promalignancy factor in breast cancer, in…”
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Concomitant expression of the chemokines RANTES and MCP-1 in human breast cancer: A basis for tumor-promoting interactions by Soria, Gali, Yaal-Hahoshen, Neora, Azenshtein, Elina, Shina, Sima, Leider-Trejo, Leonor, Ryvo, Larisa, Cohen-Hillel, Efrat, Shtabsky, Alex, Ehrlich, Marcelo, Meshel, Tsipi, Keydar, Iafa, Ben-Baruch, Adit

“…The chemokines RANTES (CCL5) and MCP-1 (CCL2) were suggested to contribute, independently, to breast malignancy. In the present study, we asked if the two…”
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MUC1 gene overexpressed in breast cancer: structure and transcriptional activity of the MUC1 promoter and role of estrogen receptor alpha (ERalpha) in regulation of the MUC1 gene expression by Zaretsky, Joseph Z, Barnea, Itay, Aylon, Yael, Gorivodsky, Marat, Wreschner, Daniel H, Keydar, Iafa

“…The MUC1 gene encodes a mucin glycoprotein(s) which is basally expressed in most epithelial cells. In breast adenocarcinoma and a variety of epithelial tumors…”
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Generation of ligand‐receptor alliances by “SEA” module‐mediated cleavage of membrane‐associated mucin proteins by Wreschner, Daniel H., McGuckin, Michael A., Williams, Stefanie J., Baruch, Amos, Yoeli, Merav, Ziv, Ravit, Okun, Liron, Zaretsky, Joseph, Smorodinsky, Nechama, Keydar, Iafa, Neophytou, Pavlos, Stacey, Martin, Lin, His‐Hsien, Gordon, Siamon

“…A mechanism is described whereby one and the same gene can encode both a receptor protein as well as its specific ligand. Generation of this receptor–ligand…”
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RAFTK/Pyk2 tyrosine kinase mediates the association of p190 RhoGAP with RasGAP and is involved in breast cancer cell invasion by ZRIHAN-LICHT, S, YIGONG FU, SETTLEMAN, J, SCHINKMANN, K, SHAW, L, KEYDAR, L, AVRAHAM, S, AVRAHAM, H

“…Focal adhesions and actin cytoskeleton are involved in cell growth, shape and movement and in tumor invasion. Mitogen-induced changes in actin cytoskeleton are…”
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Functional Analysis of Csk and CHK Kinases in Breast Cancer Cells by Bougeret, Cécile, Jiang, Shuxian, Keydar, Iafa, Avraham, Hava

“…In this report, we analyzed the expression and kinase activities of Csk and CHK kinases in normal breast tissues and breast tumors and their involvement in…”
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A Novel Protein Derived from the MUC1 Gene by Alternative Splicing and Frameshifting by Levitin, Fiana, Baruch, Amos, Weiss, Mordechai, Stiegman, Keren, Hartmann, Mor-li, Yoeli-Lerner, Merav, Ziv, Ravit, Zrihan-Licht, Sheila, Shina, Sima, Gat, Andrea, Lifschitz, Beatrice, Simha, Moshe, Stadler, Yona, Cholostoy, Alina, Gil, Benny, Greaves, David, Keydar, Iafa, Zaretsky, Joseph, Smorodinsky, Nechama, Wreschner, Daniel H.

“…Genes that have been designated the name “MUC” code for proteins comprising mucin domains. These proteins may be involved in barrier and protective functions…”
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Association of Csk-homologous Kinase (CHK) (formerly MATK) with HER-2/ErbB-2 in Breast Cancer Cells by Zrihan-Licht, Sheila, Lim, Jinkyu, Keydar, Iafa, Sliwkowski, Mark X., Groopman, Jerome E., Avraham, Hava

“…Protein-tyrosine kinases, such as HER-2/ErbB-2, have been specifically linked to breast cancer. The Csk-homologous kinase (CHK), formerly MATK, is a tyrosine…”
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Csk Homologous Kinase, a Novel Signaling Molecule, Directly Associates with the Activated ErbB-2 Receptor in Breast Cancer Cells and Inhibits Their Proliferation by Zrihan-Licht, S, Deng, B, Yarden, Y, McShan, G, Keydar, I, Avraham, H

“…Substantial evidence exists supporting direct roles for ErbB-2/neu and Src kinase activation in breast cancer. The Csk homologous kinase (CHK) is a recently…”
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DNA methylation status of the MUC1 gene coding for a breast-cancer-associated protein by Zrihan-Licht, S, Weiss, M, Keydar, I, Wreschner, D H

“…The MUC1 gene codes for protein products that are highly expressed in human breast-cancer tissue and that serve as tumor markers for disease progression. The…”
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The CC chemokine RANTES in breast carcinoma progression: Regulation of expression and potential mechanisms of promalignant activity by AZENSHTEIN, Elina, LUBOSHITS, Galia, SHINA, Sima, NEUMARK, Eran, SHAHBAZIAN, David, WEIL, Miguel, WIGLER, Nely, KEYDAR, Iafa, BEN-BARUCH, Adit

“…Breast cancer progression may be affected by various cellular components expressed by the tumor cells and/or by microenvironmental factors. Many studies report…”
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Antibody internalization studied using a novel IgG binding toxin fusion by Mazor, Yariv, Barnea, Itay, Keydar, Iafa, Benhar, Itai

“…Targeted therapy encompasses a wide variety of different strategies, which can be divided into direct or indirect approaches. Direct approaches target…”
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Preoperative diagnosis of thyroid papillary carcinoma by reverse transcriptase polymerase chain reaction of theMUC1 gene by Weiss, Mordechai, Baruch, Amos, Keydar, Iafa, Wreschner, Daniel H.

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Elevated expression of the CC chemokine Regulated on activation, normal T Cell Expressed and Secreted (RANTES) in advanced breast carcinoma by LUBOSHITS, G, SHINA, S, KAPLAN, O, ENGELBERG, S, NASS, D, LIFSHITZ-MERCER, B, CHAITCHIK, S, KEYDAR, I, BEN-BARUCH, A

“…Breast carcinoma is the most common malignant disease among women and the second most lethal one. In search for a better understanding of the role of cellular…”
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The angiogenic factors CXCL8 and VEGF in breast cancer: regulation by an array of pro-malignancy factors by Azenshtein, Elina, Meshel, Tsipi, Shina, Sima, Barak, Nely, Keydar, Iafa, Ben-Baruch, Adit

“…The regulation of secretion of the angiogenic factors CXCL8 and Vascular Endothelial Growth Factors (VEGF) was determined in breast tumor cells and in…”
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Human Endogenous Retrovirus (HERV-K) Reverse Transcriptase as a Breast Cancer Prognostic Marker123 by Golan, Maya, Hizi, Amnon, Resau, James H, Yaal-Hahoshen, Neora, Reichman, Hadar, Keydar, Iafa, Tsarfaty, Ilan

“…A reverse transcriptase (RT) cDNA, designated HERV-K-T47D-RT , was isolated from a hormonally treated human breast cancer cell line. The protein product…”
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Humanization and epitope mapping of the H23 anti-MUC1 monoclonal antibody reveals a dual epitope specificity by Mazor, Yariv, Keydar, Iafa, Benhar, Itai

“…The tumor-associated antigen MUC1 is a cell surface mucin that is expressed on the apical surface of most glandular epithelial cells, including the ducts of…”
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The breast cancer-associated MUC1 gene generates both a receptor and its cognate binding protein by BARUCH, A, HARTMANN, M.-L, WRESCHNER, D. H, YOELI, M, ADERETH, Y, GREENSTEIN, S, STADLER, Y, SKORNIK, Y, ZARETSKY, J, SMORODINSKY, N. I, KEYDAR, I

“…MUC1 proteins, some of which contain a mucin-like domain and others lacking this region, can be generated from the human breast cancer-associated MUC1 gene by…”
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Tyrosine phosphorylation of the MUC1 breast cancer membrane proteins Cytokine receptor-like molecules by Zrihan-Licht, Sheila, Baruch, Amos, Elroy-Stein, Orna, Keydar, Iafa, Wreschner, Daniel H.

“…Phosphorylation on tyrosine residues is a key step in signal transduction pathways mediated by membrane proteins. Although it is known that human breast cancer…”
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