Search Results - "Kewin Gombeau"
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Assembly-dependent translation of subunits 6 (Atp6) and 9 (Atp9) of ATP synthase in yeast mitochondria
Published in Genetics (Austin) (03-03-2022)“…Abstract The yeast mitochondrial ATP synthase is an assembly of 28 subunits of 17 types of which 3 (subunits 6, 8, and 9) are encoded by mitochondrial genes,…”
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Zebrafish exposure to environmentally relevant concentration of depleted uranium impairs progeny development at the molecular and histological levels
Published in PloS one (22-05-2017)“…Uranium is an actinide naturally found in the environment. Anthropogenic activities lead to the release of increasing amounts of uranium and depleted uranium…”
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Whole transcriptome data of zebrafish exposed to chronic dose of depleted uranium
Published in Data in brief (01-10-2017)“…The concentration of depleted uranium (DU) in the environment is expected to increase due to anthropogenic activities, posing potential risks on ecosystems…”
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Case Report: Identification of a Novel Variant (m.8909T>C) of Human Mitochondrial ATP6 Gene and Its Functional Consequences on Yeast ATP Synthase
Published in Life (Basel, Switzerland) (22-09-2020)“…With the advent of next generation sequencing, the list of mitochondrial DNA (mtDNA) mutations identified in patients rapidly and continuously expands. They…”
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Protective Effects of Plathymenia reticulata and Connarus favosus Aqueous Extracts against Cadmium- and Mercury-Induced Toxicities
Published in Toxicological research (Seoul) (01-01-2019)“…The extracts of Plathymenia reticulata and Connarus favosus are widely used in the folk medicine. The potential protective effects of these extracts have been…”
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Challenges to rhizobial adaptability in a changing climate: Genetic engineering solutions for stress tolerance
Published in Microbiological research (01-11-2024)“…Rhizobia interact with leguminous plants in the soil to form nitrogen fixing nodules in which rhizobia and plant cells coexist. Although there are emerging…”
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The pathogenic MT-ATP6 m.8851T>C mutation prevents proton movements within the n-side hydrophilic cleft of the membrane domain of ATP synthase
Published in Biochimica et biophysica acta. Bioenergetics (01-07-2019)“…Dozens of pathogenic mutations have been localized in the mitochondrial gene (MT-ATP6) that encodes the subunit a of ATP synthase. The subunit a together with…”
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Epigenetic, histopathological and transcriptomic effects following exposure to depleted uranium in adult zebrafish and their progeny
Published in Aquatic toxicology (01-03-2017)“…•The parental DU-exposure induced a significant transfer of uranium into eggs.•Du-exposed progeny exhibited a significant 2-fold increased DNA methylation…”
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Deregulating mitochondrial metabolite and ion transport has beneficial effects in yeast and human cellular models for NARP syndrome
Published in Human molecular genetics (15-11-2019)“…Abstract The m.8993T>G mutation of the mitochondrial MT-ATP6 gene has been associated with numerous cases of neuropathy, ataxia and retinitis pigmentosa and…”
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Dose-dependent genomic DNA hypermethylation and mitochondrial DNA damage in Japanese tree frogs sampled in the Fukushima Daiichi area
Published in Journal of environmental radioactivity (01-12-2020)“…The long-term consequences of the nuclear disaster at the Fukushima Daiichi Nuclear Power Plant (FDNPP) that occurred on March 2011, have been scarcely studied…”
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Depleted uranium induces sex- and tissue-specific methylation patterns in adult zebrafish
Published in Journal of environmental radioactivity (01-04-2016)“…We examined the effects of chronic exposure to different concentrations (2 and 20 μg L−1) of environmentally relevant waterborne depleted uranium (DU) on the…”
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Protective Effects of and Aqueous Extracts against Cadmium- and Mercury-Induced Toxicities
Published in Toxicological research (Seoul) (2019)“…The extracts of and are widely used in the folk medicine. The potential protective effects of these extracts have been evaluated against cadmium in the yeast ,…”
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