Search Results - "Kew, RR"

Chemotaxis of human monocyte-derived dendritic cells to complement component C1q is mediated by the receptors gC1qR and cC1qR by Vegh, Zsuzsa, Kew, Richard R., Gruber, Barry L., Ghebrehiwet, Berhane

“…Dendritic cells (DCs) are recruited to inflammatory sites where they phagocytose and process antigens for subsequent presentation to the T lymphocytes in the…”
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The Differentiation and Function of Myofibroblasts is Regulated by Mast Cell Mediators by Gailit, James, Marchese, Mary J., Kew, Richard R., Gruber, Barry L.

“…Myofibroblasts are fibroblasts that express certain features of smooth muscle differentiation. Increased numbers of myofibroblasts and mast cells are…”
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CD44 and Annexin A2 Mediate the C5a Chemotactic Cofactor Function of the Vitamin D Binding Protein by McVoy, Lauren A, Kew, Richard R

“…The vitamin D binding protein (DBP) is a plasma protein that significantly enhances the chemotactic activity of C5a and C5a(desArg) (cochemotactic activity)…”
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Identification of a Region in the Vitamin D-binding Protein that Mediates Its C5a Chemotactic Cofactor Function by Zhang, Jianhua, Kew, Richard R.

“…The vitamin D-binding protein (DBP), also known as group-specific component or Gc-globulin, is a multifunctional plasma protein that can significantly enhance…”
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Platelet-Derived Thrombospondin-1 Is Necessary for the Vitamin D-Binding Protein (Gc-Globulin) to Function as a Chemotactic Cofactor for C5a by Trujillo, Glenda, Kew, Richard R

“…The chemotactic activity of C5a and C5a des Arg can be enhanced significantly by the vitamin D-binding protein (DBP), also known as Gc-globulin. DBP is a…”
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Human mast cells activate fibroblasts: tryptase is a fibrogenic factor stimulating collagen messenger ribonucleic acid synthesis and fibroblast chemotaxis by Gruber, BL, Kew, RR, Jelaska, A, Marchese, MJ, Garlick, J, Ren, S, Schwartz, LB, Korn, JH

“…The effect of human mast cells on fibroblast activity was studied using an organotypic skin-equivalent culture system. Human mast cell-1 (HMC-1) cells were…”
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Protease-Activated Receptor-2 (PAR-2) Expression in Human Fibroblasts is Regulated by Growth Factors and Extracellular Matrix by Gruber, Barry L., Marchese, Mary J., Santiago-Schwarz, Frances, Martin, Carla A., Zhang, Jianhua, Kew, Richard R.

“…Many cell types express a membrane receptor, activated by trypsin-like proteases, termed protease-activated receptor-2 (PAR-2). Previous studies describing…”
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Transforming growth factor-beta 1 mediates mast cell chemotaxis by Gruber, BL, Marchese, MJ, Kew, RR

“…It remains unknown which factor(s) control mast cell recruitment in chronic immune reactions. Although TGF-beta has been shown to function as a potent…”
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Initial Characterization of the Vitamin D Binding Protein (Gc-Globulin) Binding Site on the Neutrophil Plasma Membrane: Evidence for a Chondroitin Sulfate Proteoglycan by DiMartino, Stephen J, Kew, Richard R

“…The vitamin D binding protein (DBP) is a multifunctional plasma protein that can modulate certain immune and inflammatory responses. The diverse cellular…”
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Elastase Controls the Binding of the Vitamin D-Binding Protein (Gc-Globulin) to Neutrophils: A Potential Role in the Regulation of C5a Co-Chemotactic Activity by DiMartino, Stephen J, Shah, Anisha B, Trujillo, Glenda, Kew, Richard R

“…The vitamin D-binding protein (DBP) binds to the plasma membranes of numerous cell types and mediates a diverse array of cellular functions. DBP bound to the…”
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Borrelia burgdorferi binds plasminogen, resulting in enhanced penetration of endothelial monolayers by COLEMAN, J. L, SELLATI, T. J, TESTA, J. E, KEW, R. R, FURIE, M. B, BENACH, J. L

“…Services IAI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit StumbleUpon…”
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Gc-globulin (vitamin D-binding protein) enhances the neutrophil chemotactic activity of C5a and C5a des Arg by Kew, R R, Webster, R O

“…Several serum proteins have been shown to be important in modulating leukocyte chemotaxis and inflammation. We investigated the possibility that the…”
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Co-chemotactic effect of Gc-globulin (vitamin D binding protein) for C5a. Transient conversion into an active co-chemotaxin by neutrophils by Kew, RR, Fisher, JA, Webster, RO

“…Gc-globulin (vitamin D binding protein) has been shown to augment significantly the leukocyte chemotactic activity of the activated C peptides C5a and…”
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Murine mast cells express two types of C1q receptors that are involved in the induction of chemotaxis and chemokinesis by Ghebrehiwet, B, Kew, RR, Gruber, BL, Marchese, MJ, Peerschke, EI, Reid, KB

“…Although previous studies have shown that different cells and cell lines of murine origin bind human C1q, suggesting that they display cell surface receptors…”
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Undifferentiated U937 cells transfected with chemoattractant receptors: a model system to investigate chemotactic mechanisms and receptor structure/function relationships by Kew, Richard R., Peng, Tina, DiMartino, Stephen J., Madhavan, Deepa, Weinman, Shana J., Cheng, Daniel, Prossnitz, Eric R.

“…Transfection of either the C5a receptor or the formyl peptide receptor into undifferentiated U937 cells generated continuously growing cell lines that stably…”
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Mast cell tryptase does not alter matrix metalloproteinase expression in human dermal fibroblasts: Further evidence that proteolytically-active tryptase is a potent fibrogenic factor by Zhang, Jianhua, Gruber, Barry L., Marchese, Mary J., Zucker, Stanley, Schwartz, Lawrence B., Kew, Richard R.

“…There is compelling in vitro and in vivo evidence to implicate mast cells in the development of fibrosis. However, an important question remains as to the…”
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Human neutrophil Fc gamma RIIIB and formyl peptide receptors are functionally linked during formyl-methionyl-leucyl-phenylalanine- induced chemotaxis by Kew, RR, Grimaldi, CM, Furie, MB, Fleit, HB

“…The formyl peptide receptor (FPR) and the glycosyl-phosphatidylinositol-linked type III receptor for the Fc portion of IgG (Fc gamma RIIIB; CD16) play…”
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Initial Characterization of the Complement Activating Compounds in Extracts of Smokeless Tobacco by Chan, Wai-Sae, Chowdhry, Saurabh, Chang, Tunhan, Kew, Richard R.

“…Aqueous extracts of smokeless tobacco (ST) have been shown to be potent activators of complement. However, the mechanisms by which smokeless tobacco activates…”
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Localization and Quantitation of the Vitamin D Binding Protein (Gc-Globulin) in Human Neutrophils by Kew, Richard R., Sibug, Maria A., Liuzzo, John P., Webster, Robert O.

“…Plasma-derived vitamin D binding protein (DBP) is an important physiologic regulator of the neutrophil chemotactic response to activated complement. A…”
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Inhibition of neutrophil chemotaxis by protease inhibitors. Differential effect of inhibitors of serine and thiol proteases by Barna, J B, Kew, R R

“…Previous studies have demonstrated that neutrophils possess an active serine protease(s) which may be involved in the process of chemotaxis but the precise…”
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