Search Results - "Kevin Mayo"

Chemokines from a Structural Perspective by Miller, Michelle C, Mayo, Kevin H

“…Chemokines are a family of small, highly conserved cytokines that mediate various biological processes, including chemotaxis, hematopoiesis, and angiogenesis,…”
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Heterologous Interactions with Galectins and Chemokines and Their Functional Consequences by Mayo, Kevin H

“…Extra- and intra-cellular activity occurs under the direction of numerous inter-molecular interactions, and in any tissue or cell, molecules are densely…”
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Galectins as Molecular Targets for Therapeutic Intervention by Dings, Ruud P M, Miller, Michelle C, Griffin, Robert J, Mayo, Kevin H

“…Galectins are a family of small, highly conserved, molecular effectors that mediate various biological processes, including chemotaxis and angiogenesis, and…”
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Prof. Hans-Joachim Gabius (1955-2021) A Tribute to an Outstanding Glycobiologist, Mentor and Friend by Kaltner, Herbert, Mayo, Kevin H

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Pectic polysaccharides from Radix Sophorae Tonkinensis exhibit significant antioxidant effects by Ning, Xin, Liu, Ying, Jia, Mengdi, Wang, Qidi, Sun, Ziyan, Ji, Li, Mayo, Kevin H., Zhou, Yifa, Sun, Lin

“…•Two pectic polysaccharides were purified from Radix Sophorae Tonkinensis.•They both contained HG, RG-I and RG-II domains with different mass ratios.•RG-I…”
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Glucosyltransferase TeGSS from Thermosynechococcus elongatus produces an α-1,2-glucan by Qu, Xiaoyu, An, Qinghui, Sayed, Hend, Cui, Liangnan, Mayo, Kevin H., Su, Jiyong

“…Here, we enzymatically produced a novel α-1,2-glucan, glucosylsucrose, that has a chemical structure significantly different from that of other glucans. This…”
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Emodin inhibits aggregation of amyloid‐β peptide 1–42 and improves cognitive deficits in Alzheimer's disease transgenic mice by Wang, Lichun, Liu, Sitong, Xu, Jiaqi, Watanabe, Nobumoto, Mayo, Kevin H., Li, Jiang, Li, Xiaomeng

“…Aggregation of amyloid‐β peptide 1–42 (Aβ42) initiates the onset of Alzheimer's disease (AD), and all the drugs designed to attenuate AD have failed in…”
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The model polysaccharide potato galactan is actually a mixture of different polysaccharides by Feng, Zhangkai, Lin, Zhiying, Tang, Huazhi, Geng, Jie, Hu, Yanbo, Mayo, Kevin H., Tai, Guihua, Zhou, Yifa

“…Commercially-supplied potato galactan (PG) is widely used as a model polysaccharide in various bioactivity studies. However, results using this galactan are…”
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Structure and antioxidant activity of six mushroom-derived heterogalactans by Qu, Yunhe, Yan, Jingmin, Zhang, Xin, Song, Chengcheng, Zhang, Mengshan, Mayo, Kevin H., Sun, Lin, Cheng, Hairong, Zhou, Yifa

“…Heterogalactans with weight-average molecular weights ~20 kDa were purified from several species of mushroom: Hypsizygus marmoreus, Pleurotus ostreatus,…”
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Oligosaccharides from Stellaria dichotoma L. var. lanceolate bind to galectin-3 and ameliorate effects of colitis by Zhao, Zihan, Wu, Jing, Xu, Xuejiao, He, Zhen, Wang, Xiang, Su, Jiyong, Mayo, Kevin H., Sun, Lin, Cui, Liangnan, Zhou, Yifa

“…Even though Stellaria dichotoma L. var. lanceolate (S. dichotoma) is a well-known medicinal plant in the family Caryophyllaceae, its oligosaccharides remain…”
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Application of an α-galactosidase from Bacteroides fragilis on structural analysis of raffinose family oligosaccharides by Zu, Heyang, Yan, Xuecui, Wu, Jing, Zhao, Jingying, Mayo, Kevin H., Zhou, Yifa, Cui, Liangnan, Cheng, Hairong, Sun, Lin

“…Raffinose family oligosaccharides (RFOs) have diverse structures and exhibit various biological activities. When using RFOs as prebiotics, their structures…”
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An efficient protocol for preparing linear β-manno-oligosaccharides by Cui, Liangnan, Wang, Xiang, Wang, Chao, Yan, Yue, Zhang, Mengshan, Mayo, Kevin H., Sun, Lin, Zhou, Yifa

“…Linear β-manno-oligosaccharides (l-β-MOS) are widely used to investigate oligo- and poly-saccharide structures and mannanolytic enzyme activities. l-β-MOS are…”
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Structure–function studies of galectin‐14, an important effector molecule in embryology by Si, Yunlong, Li, Yuying, Yang, Tong, Li, Xumin, Ayala, Gabriela Jaramillo, Mayo, Kevin H., Tai, Guihua, Su, Jiyong, Zhou, Yifa

“…The expression of prototype galectin‐14 (Gal‐14) in human placenta is higher than any other galectin, suggesting that it may play a role in fetal development…”
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The marriage of chemokines and galectins as functional heterodimers by von Hundelshausen, Philipp, Wichapong, Kanin, Gabius, Hans-Joachim, Mayo, Kevin H.

“…Trafficking of leukocytes and their local activity profile are of pivotal importance for many (patho)physiological processes. Fittingly, microenvironments are…”
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Galectin-3 N-terminal tail prolines modulate cell activity and glycan-mediated oligomerization/phase separation by Zhao, Zihan, Xu, Xuejiao, Cheng, Hairong, Miller, Michelle C., He, Zhen, Gu, Hongming, Zhang, Zhongyu, Raz, Avraham, Mayo, Kevin H., Tai, Guihua, Zhou, Yifa

“…Galectin-3 (Gal-3) has a long, aperiodic, and dynamic proline-rich N-terminal tail (NT). The functional role of the NT with its numerous prolines has remained…”
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Preparation of individual galactan oligomers, their prebiotic effects, and use in estimating galactan chain length in pectin-derived polysaccharides by Zheng, Yi, Li, Leisheng, Feng, Zhangkai, Wang, Hao, Mayo, Kevin H., Zhou, Yifa, Tai, Guihua

“…•Individual galactan oligomers (GOs) up to DP15 were prepared and characterized.•GOs were analyzed by 1H-13C HSQC/HMBC NMR and their resonances…”
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Comparative study on the structures of intra- and extra-cellular polysaccharides from Penicillium oxalicum and their inhibitory effects on galectins by Zhang, Siying, Qiao, Zhonghui, Zhao, Zihan, Guo, Jiao, Lu, Kaiwen, Mayo, Kevin H., Zhou, Yifa

“…Here, we compare the content and composition of polysaccharides derived from the mycelium (40.4 kDa intracellular polysaccharide, IPS) and culture (27.2 kDa…”
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Heterogalactan WPEP-N-b from Pleurotus eryngii enhances immunity in immunocompromised mice by Chen, Lei, Ren, Ai, Wang, Yushi, Qu, Yunhe, Gong, Hesong, Mayo, Kevin H., Zhou, Yifa, Cheng, Hairong

“…This study reports on in vivo immunomodulatory activities mediated by WPEP-N-b, a heterogalactan from Pleurotus eryngii. Using cyclophosphamide (CTX)–induced…”
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Galactofuranose side chains in galactomannans from Penicillium spp. modulate galectin-8-mediated bioactivity by Zhang, Siying, Lin, Zhiying, Wang, Dongmei, Xu, Xuejiao, Song, Chengcheng, Sun, Lin, Mayo, Kevin H., Zhao, Zihan, Zhou, Yifa

“…Polysaccharides from fungi have many bioactivities. Previous studies showed that galactomannans from Penicillium oxalicum antagonize galectin-8-mediated…”
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Comparative study of water-soluble polysaccharides isolated from leaves and roots of Isatis indigotica Fort by Pak, UnHak, Yu, Yang, Ning, Xin, Ho, ChungHyok, Ji, Li, Mayo, Kevin H., Zhou, Yifa, Sun, Lin

“…Water-soluble polysaccharides were isolated from the leaves and roots of Isatis indigotica Fort., and their structural features were studied and compared. One…”
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