Search Results - "Kevin, Richard"

The Genotypic View of Social Interactions in Microbial Communities by Mitri, Sara, Richard Foster, Kevin

“…Dense and diverse microbial communities are found in many environments. Disentangling the social interactions between strains and species is central to…”
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Cannabidiol (CBD) content in vaporized cannabis does not prevent tetrahydrocannabinol (THC)-induced impairment of driving and cognition by Arkell, Thomas R., Lintzeris, Nicholas, Kevin, Richard C., Ramaekers, Johannes G., Vandrey, Ryan, Irwin, Christopher, Haber, Paul S., McGregor, Iain S.

“…Background The main psychoactive component of cannabis, delta-9-tetrahydrocannabinol (THC), can impair driving performance. Cannabidiol (CBD), a…”
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Synthesis and in Vitro Cannabinoid Receptor 1 Activity of Recently Detected Synthetic Cannabinoids 4F-MDMB-BICA, 5F-MPP-PICA, MMB-4en-PICA, CUMYL-CBMICA, ADB-BINACA, APP-BINACA, 4F-MDMB-BINACA, MDMB-4en-PINACA, A‑CHMINACA, 5F-AB-P7AICA, 5F-MDMB-P7AICA, and 5F-AP7AICA by Cannaert, Annelies, Sparkes, Eric, Pike, Edward, Luo, Jia Lin, Fang, Ada, Kevin, Richard C, Ellison, Ross, Gerona, Roy, Banister, Samuel D, Stove, Christophe P

“…Synthetic cannabinoid receptor agonists (SCRAs) are an evolving class of new psychoactive substances (NPS) with structurally diverse compounds emerging each…”
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Effects of cannabidiol on simulated driving and cognitive performance: A dose-ranging randomised controlled trial by McCartney, Danielle, Suraev, Anastasia S, Doohan, Peter T, Irwin, Christopher, Kevin, Richard C, Grunstein, Ronald R, Hoyos, Camilla M, McGregor, Iain S

“…Background: Cannabidiol (CBD), a major cannabinoid of Cannabis sativa, is widely consumed in prescription and non-prescription products. While CBD is generally…”
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Pharmacology of Indole and Indazole Synthetic Cannabinoid Designer Drugs AB-FUBINACA, ADB-FUBINACA, AB-PINACA, ADB-PINACA, 5F-AB-PINACA, 5F-ADB-PINACA, ADBICA, and 5F-ADBICA by Banister, Samuel D, Moir, Michael, Stuart, Jordyn, Kevin, Richard C, Wood, Katie E, Longworth, Mitchell, Wilkinson, Shane M, Beinat, Corinne, Buchanan, Alexandra S, Glass, Michelle, Connor, Mark, McGregor, Iain S, Kassiou, Michael

“…Synthetic cannabinoid (SC) designer drugs based on indole and indazole scaffolds and featuring l-valinamide or l-tert-leucinamide side chains are encountered…”
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Citalopram and Cannabidiol: In Vitro and In Vivo Evidence of Pharmacokinetic Interactions Relevant to the Treatment of Anxiety Disorders in Young People by Anderson, Lyndsey L., Doohan, Peter T., Oldfield, Lachlan, Kevin, Richard C., Arnold, Jonathon C., Berger, Maximus, Amminger, G. Paul, McGregor, Iain S.

“…Cannabidiol (CBD), a major nonintoxicating constituent of cannabis, exhibits anxiolytic properties in preclinical and human studies and is of interest as a…”
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Defensive aggregation (huddling) in Rattus norvegicus toward predator odor: individual differences, social buffering effects and neural correlates by Bowen, Michael T, Kevin, Richard C, May, Matthew, Staples, Lauren G, Hunt, Glenn E, McGregor, Iain S

“…Aggregation is a defensive strategy employed by many prey species in response to predatory threat. Our group has characterized defensive aggregation (huddling)…”
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Laboratory Comparison of Low-Cost Particulate Matter Sensors to Measure Transient Events of Pollution by Bulot, Florentin Michel Jacques, Russell, Hugo Savill, Rezaei, Mohsen, Johnson, Matthew Stanley, Ossont, Steven James Johnston, Morris, Andrew Kevin Richard, Basford, Philip James, Easton, Natasha Hazel Celeste, Foster, Gavin Lee, Loxham, Matthew, Cox, Simon James

“…Airborne particulate matter (PM) exposure has been identified as a key environmental risk factor, associated especially with diseases of the respiratory and…”
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An open-label feasibility trial of transdermal cannabidiol for hand osteoarthritis by Bawa, Zeeta, Lewis, Daniel, Gavin, Paul D., Libinaki, Roksan, Joubran, Lida, El-Tamimy, Mahmoud, Taylor, Greg, Meltzer, Ryan, Bedoya-Pérez, Miguel, Kevin, Richard C., McGregor, Iain S.

“…Hand osteoarthritis (OA) is an irreversible degenerative condition causing chronic pain and impaired functionality. Existing treatment options are often…”
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Molecular and Behavioral Pharmacological Characterization of Abused Synthetic Cannabinoids MMB- and MDMB-FUBINACA, MN-18, NNEI, CUMYL-PICA, and 5-Fluoro-CUMYL-PICA by Gamage, Thomas F, Farquhar, Charlotte E, Lefever, Timothy W, Marusich, Julie A, Kevin, Richard C, McGregor, Iain S, Wiley, Jenny L, Thomas, Brian F

“…Synthetic cannabinoids are a class of novel psychoactive substances that exhibit high affinity at the cannabinoid type-1 (CB ) receptor and produce effects…”
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Cannabidiol disrupts conditioned fear expression and cannabidiolic acid reduces trauma-induced anxiety-related behaviour in mice by Assareh, Neda, Gururajan, Anand, Zhou, Cilla, Luo, Jia Lin, Kevin, Richard C., Arnold, Jonathon C.

“…The major phytocannabinoid cannabidiol (CBD) has anxiolytic properties and lacks tetrahydrocannabinol-like psychoactivity. Cannabidiolic acid (CBDA) is the…”
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Are blood and oral fluid Δ9-tetrahydrocannabinol (THC) and metabolite concentrations related to impairment? A meta-regression analysis by McCartney, Danielle, Arkell, Thomas R., Irwin, Christopher, Kevin, Richard C., McGregor, Iain S.

“…•THC-related biomarkers were associated with impairment in occasional cannabis users.•However, most of these ‘biomarker–performance’ relationships were ‘weak’…”
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Effects of Bioisosteric Fluorine in Synthetic Cannabinoid Designer Drugs JWH-018, AM-2201, UR-144, XLR-11, PB-22, 5F-PB-22, APICA, and STS-135 by Banister, Samuel D, Stuart, Jordyn, Kevin, Richard C, Edington, Amelia, Longworth, Mitchell, Wilkinson, Shane M, Beinat, Corinne, Buchanan, Alexandra S, Hibbs, David E, Glass, Michelle, Connor, Mark, McGregor, Iain S, Kassiou, Michael

“…Synthetic cannabinoid (SC) designer drugs featuring bioisosteric fluorine substitution are identified by forensic chemists and toxicologists with increasing…”
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Off-target pharmacological profiling of synthetic cannabinoid receptor agonists including AMB-FUBINACA, CUMYL-PINACA, PB-22, and XLR-11 by Kevin, Richard C, Cairns, Elizabeth A, Boyd, Rochelle, Arnold, Jonathon C, Bowen, Michael T, McGregor, Iain S, Banister, Samuel D

“…Synthetic cannabinoid receptor agonists (SCRAs) are a diverse class of new psychoactive substances that have been associated with multiple instances and types…”
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Sex differences in acute cannabis effects revisited: Results from two randomized, controlled trials by Arkell, Thomas R., Kevin, Richard C., Vinckenbosch, Frederick, Lintzeris, Nicholas, Theunissen, Eef, Ramaekers, Johannes G., McGregor, Iain S.

“…Some evidence suggests that males and females may differ in their responses to acute cannabis effects, including subjective drug effects and behavioural…”
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Pharmacology of Cumyl-Carboxamide Synthetic Cannabinoid New Psychoactive Substances (NPS) CUMYL-BICA, CUMYL-PICA, CUMYL-5F-PICA, CUMYL-5F-PINACA, and Their Analogues by Longworth, Mitchell, Banister, Samuel D, Boyd, Rochelle, Kevin, Richard C, Connor, Mark, McGregor, Iain S, Kassiou, Michael

“…Synthetic cannabinoids (SC) are the largest class of new psychoactive substances (NPS), and are increasingly associated with serious adverse effects. The…”
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A phase II randomised controlled trial of intranasal oxytocin in anorexia nervosa by Maguire, Sarah, Kesby, Alice, Brownlow, Rachel, Hunt, Glenn E., Kim, Marcellinus, McAulay, Claire, Grisham, Jessica R., McGregor, Iain S., Suraev, Anastasia, Kevin, Richard C., Russell, Janice

“…Anorexia nervosa (AN) is an eating disorder (ED) with high mortality rates and limited response to existing treatments, prompting the need to identify…”
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Synthetic Cannabinoid Hydroxypentyl Metabolites Retain Efficacy at Human Cannabinoid Receptors by Gamage, Thomas F, Farquhar, Charlotte E, McKinnie, Ryan J, Kevin, Richard C, McGregor, Iain S, Trudell, Mark L, Wiley, Jenny L, Thomas, Brian F

“…Synthetic cannabinoids (SCs) are novel psychoactive substances that are easily acquired, widely abused as a substitute for cannabis, and associated with…”
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Thermolytic Degradation of Synthetic Cannabinoids: Chemical Exposures and Pharmacological Consequences by Thomas, Brian F, Lefever, Timothy W, Cortes, Ricardo A, Grabenauer, Megan, Kovach, Alexander L, Cox, Anderson O, Patel, Purvi R, Pollard, Gerald T, Marusich, Julie A, Kevin, Richard C, Gamage, Thomas F, Wiley, Jenny L

“…Synthetic cannabinoids are manufactured clandestinely with little quality control and are distributed as herbal "spice" for smoking or as bulk compound for…”
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MEPIRAPIM-derived synthetic cannabinoids inhibit T-type calcium channels with divergent effects on seizures in rodent models of epilepsy by Harman, Thomas, Udoh, Michael, McElroy, Dan L, Anderson, Lyndsey L, Kevin, Richard C, Banister, Samuel D, Ametovski, Adam, Markham, Jack, Bladen, Chris, Doohan, Peter T, Greba, Quentin, Laprairie, Robert B, Snutch, Terrance P, McGregor, Iain S, Howland, John G, Arnold, Jonathon C

“…T-type Ca channels (Ca 3) represent emerging therapeutic targets for a range of neurological disorders, including epilepsy and pain. To aid the development and…”
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