Search Results - "Kevin, BECCARIA"

Histone H3 wild-type DIPG/DMG overexpressing EZHIP extend the spectrum diffuse midline gliomas with PRC2 inhibition beyond H3-K27M mutation by Castel, David, Kergrohen, Thomas, Tauziède-Espariat, Arnault, Mackay, Alan, Ghermaoui, Samia, Lechapt, Emmanuèle, Pfister, Stefan M., Kramm, Christof M., Boddaert, Nathalie, Blauwblomme, Thomas, Puget, Stéphanie, Beccaria, Kévin, Jones, Chris, Jones, David T. W., Varlet, Pascale, Grill, Jacques, Debily, Marie-Anne

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Clinical trial of blood-brain barrier disruption by pulsed ultrasound by Carpentier, Alexandre, Canney, Michael, Vignot, Alexandre, Reina, Vincent, Beccaria, Kevin, Horodyckid, Catherine, Karachi, Carine, Leclercq, Delphine, Lafon, Cyril, Chapelon, Jean-Yves, Capelle, Laurent, Cornu, Philippe, Sanson, Marc, Hoang-Xuan, Khê, Delattre, Jean-Yves, Idbaih, Ahmed

“…The blood-brain barrier (BBB) limits the delivery of systemically administered drugs to the brain. Methods to circumvent the BBB have been developed, but none…”
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Clonally Expanded T Cells Reveal Immunogenicity of Rhabdoid Tumors by Leruste, Amaury, Tosello, Jimena, Ramos, Rodrigo Nalio, Tauziède-Espariat, Arnault, Brohard, Solène, Han, Zhi-Yan, Beccaria, Kevin, Andrianteranagna, Mamy, Caudana, Pamela, Nikolic, Jovan, Chauvin, Céline, Niborski, Leticia Laura, Manriquez, Valeria, Richer, Wilfrid, Masliah-Planchon, Julien, Grossetête-Lalami, Sandrine, Bohec, Mylene, Lameiras, Sonia, Baulande, Sylvain, Pouponnot, Celio, Coulomb, Aurore, Galmiche, Louise, Surdez, Didier, Servant, Nicolas, Helft, Julie, Sedlik, Christine, Puget, Stéphanie, Benaroch, Philippe, Delattre, Olivier, Waterfall, Joshua J., Piaggio, Eliane, Bourdeaut, Franck

“…Rhabdoid tumors (RTs) are genomically simple pediatric cancers driven by the biallelic inactivation of SMARCB1, leading to SWI/SNF chromatin remodeler complex…”
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Immunohistochemistry as a tool to identify ELP1-associated medulloblastoma by Tauziède-Espariat, Arnault, Guerrini-Rousseau, Léa, Perrier, Alexandre, Torrejon, Jacob, Bernardi, Flavia, Varlet, Pascale, Hasty, Lauren, Delattre, Olivier, Beccaria, Kévin, Métais, Alice, Ayrault, Olivier, Chrétien, Fabrice, Bourdeaut, Franck, Dufour, Christelle, Masliah-Planchon, Julien

“…Abstract Pediatric spinal low-grade glioma (LGG) and glioneuronal tumours are rare, accounting for less 2.8–5.2% of pediatric LGG. New tumour types frequently…”
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A comprehensive histomolecular characterization of meningioangiomatosis: Further evidence for a precursor neoplastic lesion by Tauziède‐Espariat, Arnault, Masliah‐Planchon, Julien, Sievers, Philipp, Sahm, Felix, Dangouloff‐Ros, Volodia, Boddaert, Nathalie, Hasty, Lauren, Aboubakr, Oumaima, Métais, Alice, Chrétien, Fabrice, Roux, Alexandre, Pallud, Johan, Blauwblomme, Thomas, Beccaria, Kévin, Bourdeaut, Franck, Puget, Stéphanie, Varlet, Pascale

“…Meningioangiomatosis (MAM) remains a poorly understood lesion responsible for epileptic disease. In the past, MAM was primarily described in the context of…”
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“Hemispheric pilocytic astrocytoma” revisited: A comprehensive clinicopathological and molecular series emphasizing their overlap with other glioneuronal tumors by Mariet, Cassandra, Grill, Jacques, Ajlil, Yassine, Castel, David, Dangouloff-Ros, Volodia, Boddaert, Nathalie, Meurgey, Alexandra, Pissaloux, Daniel, Appay, Romain, Saffroy, Raphaël, Puget, Stéphanie, Blauwblomme, Thomas, Beccaria, Kévin, Hasty, Lauren, Rigau, Valérie, Roujeau, Thomas, Aline-Fardin, Aude, Chrétien, Fabrice, Métais, Alice, Varlet, Pascale, Tauziède-Espariat, Arnault

“…Abstract Pilocytic astrocytomas (PA) typically exhibit distinct clinical, radiological, histopathological, and genetic features. DNA-methylation profiling…”
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A comprehensive analysis of infantile central nervous system tumors to improve distinctive criteria for infant‐type hemispheric glioma versus desmoplastic infantile ganglioglioma/astrocytoma by Tauziède‐Espariat, Arnault, Beccaria, Kévin, Dangouloff‐Ros, Volodia, Sievers, Philipp, Meurgey, Alexandra, Pissaloux, Daniel, Appay, Romain, Saffroy, Raphaël, Grill, Jacques, Mariet, Cassandra, Bourdeaut, Franck, Hasty, Lauren, Métais, Alice, Chrétien, Fabrice, Blauwblomme, Thomas, Puget, Stéphanie, Boddaert, Nathalie, Varlet, Pascale

“…Recent epigenomic analyses have revealed the existence of a new DNA methylation class (MC) of infant‐type hemispheric glioma (IHG). Like desmoplastic infantile…”
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Temporosylvian arachnoid cysts in children. Part 1: Cognitive profile of children with a temporal cyst and impact of the cyst in daily life. A prospective study in 100 consecutive children by Cuny, Marie-Laure, Vaivre-Douret, Laurence, Piana, Hélène, Blauwblomme, Thomas, Beccaria, Kévin, Paternoster, Giovanna, Bourgeois, Marie, James, Syril, Zerah, Michel, Prodhomme, Julie, Esnault, Eglantine, Cozzo, Mathilde, Trousson, Clémence, Navarro, Béatrice, Stricker, Sarah, Boddaert, Nathalie, Sainte-Rose, Christian, Piolino, Pascale, Puget, Stephanie

“…The aim of this study was to determine the cognitive profile of children with a temporal arachnoid cyst (TAC) and its impact on daily life. The authors…”
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New in vivo avatars of diffuse intrinsic pontine gliomas (DIPG) from stereotactic biopsies performed at diagnosis by Plessier, Alexandre, Le Dret, Ludivine, Varlet, Pascale, Beccaria, Kévin, Lacombe, Joëlle, Mériaux, Sébastien, Geffroy, Françoise, Fiette, Laurence, Flamant, Patricia, Chrétien, Fabrice, Blauwblomme, Thomas, Puget, Stéphanie, Grill, Jacques, Debily, Marie-Anne, Castel, David

“…Diffuse Instrinsic Pontine Glioma is the most aggressive form of High Grade Gliomas in children. The lack of biological material and the absence of relevant…”
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A CBF decrease in the left supplementary motor areas: New insight into postoperative pediatric cerebellar mutism syndrome using arterial spin labeling perfusion MRI by Boisgontier, Jennifer, Fillon, Ludovic, Rutten, Caroline, Saitovitch, Ana, Dufour, Christelle, Lemaître, Hervé, Beccaria, Kévin, Blauwblomme, Thomas, Levy, Raphaël, Dangouloff-Ros, Volodia, Grévent, David, Roux, Charles-Joris, Grill, Jacques, Vinçon-Leite, Alice, Saidoun, Lila, Bourdeaut, Franck, Zilbovicius, Monica, Boddaert, Nathalie, Puget, Stéphanie

“…Postoperative pediatric cerebellar mutism syndrome (pCMS), characterized mainly by delayed onset transient mutism is a poorly understood complication that may…”
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Brain abscess in children, a two-centre audit: outcomes and controversies by Gilard, Vianney, Beccaria, Kévin, Hartley, John C, Blanot, Stéphane, Marqué, Sophie, Bourgeois, Marie, Puget, Stephanie, Thompson, Dominic, Zerah, Michel, Tisdall, Martin

“…ObjectiveThe aim of this study was to better characterise clinical presentation, management and outcome in infants and children with brain abscess.MethodsThe…”
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VRK3 depletion induces cell cycle arrest and metabolic reprogramming of pontine diffuse midline glioma - H3K27 altered cells by Menez, Virginie, Kergrohen, Thomas, Shasha, Tal, Silva-Evangelista, Claudia, Le Dret, Ludivine, Auffret, Lucie, Subecz, Chloé, Lancien, Manon, Ajlil, Yassine, Vilchis, Irma Segoviano, Beccaria, Kévin, Blauwblomme, Thomas, Oberlin, Estelle, Grill, Jacques, Castel, David, Debily, Marie-Anne

“…We previously identified VRK3 as a specific vulnerability in DMG-H3K27M cells in a synthetic lethality screen targeting the whole kinome. The aim of the…”
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An integrative histopathological and epigenetic characterization of primary intracranial mesenchymal tumors, FET:CREB‐fused broadening the spectrum of tumor entities in comparison with their soft tissue counterparts by Tauziède‐Espariat, Arnault, Sievers, Philipp, Larousserie, Frédérique, Benzakoun, Joseph, Guillemot, Delphine, Pierron, Gaëlle, Duchesne, Mathilde, Uro‐Coste, Emmanuelle, Roux, Alexandre, Vasiljevic, Alexandre, Fenouil, Tanguy, Meyronet, David, Mokhtari, Karima, Polivka, Marc, Rousseau, Audrey, Bost‐Bezeaud, Frédérique, Akoury, Samir, Pallud, Johan, Benevello, Chiara, Hasty, Lauren, Gareton, Albane, Lechapt, Emmanuèle, Chrétien, Fabrice, Blauwblomme, Thomas, Beccaria, Kévin, Puget, Stéphanie, Sahm, Felix, Varlet, Pascale

“…FET:CREB fusions have been described in a variety of tumors from various phenotypes. Recently, these fusion transcripts were reported in intracranial tumors,…”
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GH and Childhood-onset Craniopharyngioma: When to Initiate GH Replacement Therapy? by Nguyen Quoc, Adrien, Beccaria, Kévin, González Briceño, Laura, Pinto, Graziella, Samara-Boustani, Dinane, Stoupa, Athanasia, Beltrand, Jacques, Besançon, Alix, Thalassinos, Caroline, Puget, Stéphanie, Blauwblomme, Thomas, Alapetite, Claire, Bolle, Stéphanie, Doz, François, Grill, Jacques, Dufour, Christelle, Bourdeaut, Franck, Abbou, Samuel, Guerrini-Rousseau, Léa, Leruste, Amaury, Brabant, Séverine, Cavadias, Iphigénie, Viaud, Magali, Boddaert, Nathalie, Polak, Michel, Kariyawasam, Dulanjalee

“…Abstract Context Craniopharyngioma is a benign brain tumor with frequent local recurrence or progression after treatment. GH replacement therapy (GHRT) is…”
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Clinico-Radio-Histo-Molecular and Neurocognitive Characteristics of Diffuse Gliomas in Adolescent and Young Adults: A Comprehensive Review by Roux, Alexandre, Zanello, Marc, Antonia Simboli, Giorgia, Varlet, Pascale, Tauziede-Espariat, Arnault, Beccaria, Kévin, Blauwblomme, Thomas, Puget, Stéphanie, Oppenheim, Catherine, Dangouloff-Ros, Volodia, Boddaert, Nathalie, Dhermain, Frédéric, Dufour, Christelle, Grill, Jacques, Chretien, Fabrice, Pallud, Johan

“…Diffuse gliomas are the most frequent neoplasms in adolescent and young adults (AYAs), especially high-grade gliomas, which have the highest mortality rate…”
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Postzygotic mosaicism of SMARCB1 variants in patients with rhabdoid tumors: A not-so-rare condition exposing to successive tumors by Thomson, Grégory, Filser, Mathilde, Guerrini-Rousseau, Léa, Tauziede-Espariat, Arnault, Bourneix, Christine, Gauthier-Villars, Marion, Simaga, Fatoumata, Beccaria, Kévin, Faure-Conter, Cécile, Maureille, Aurélien, Zattara-Cannoni, Hélène, Andre, Nicolas, Entz-Werle, Natacha, Brugieres, Laurence, Mansuy, Ludovic, Denizeau, Philippe, Julia, Sophie, Ingster, Olivier, Lejeune, Sophie, Brahimi, Afane, Coupier, Isabelle, Bonadona, Valérie, Delattre, Olivier, Masliah-Planchon, Julien, Bourdeaut, Franck

“…Rhabdoid tumors (RT) are aggressive, rare tumors predominantly affecting young children, characterized by biallelic SMARCB1 gene inactivation. While most…”
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Diagnostic accuracy of a minimal immunohistochemical panel in at/rt molecular subtyping, correlated to dna-methylation profiling by Tauziède-Espariat, Arnault, Masliah-Planchon, Julien, Andrianteranagna, Mamy, Sievers, Philipp, Sahm, Felix, von Deimling, Andreas, Hasty, Lauren, Delattre, Olivier, Beccaria, Kévin, Métais, Alice, Chrétien, Fabrice, Varlet, Pascale, Bourdeaut, Franck

“…Keywords: AT/RT, DNA-methylation profiling, TYR, SHH, MYC, Immunohistochemistry…”
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Pediatric high-grade glioma MYCN is frequently associated with Li-Fraumeni syndrome by Guerrini-Rousseau, Léa, Tauziède-Espariat, Arnault, Castel, David, Rouleau, Etienne, Sievers, Philipp, Saffroy, Raphaël, Beccaria, Kévin, Blauwblomme, Thomas, Hasty, Lauren, Bourdeaut, Franck, Grill, Jacques, Varlet, Pascale, Debily, Marie-Anne

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Long-term weight gain in children with craniopharyngioma by Rovani, Sibylle, Butler, Victoria, Samara-Boustani, Dinane, Pinto, Graziella, Gonzalez-Briceno, Laura, Nguyen Quoc, Adrien, Vermillac, Gaëlle, Stoupa, Athanasia, Besançon, Alix, Beltrand, Jacques, Thalassinos, Caroline, Flechtner, Isabelle, Dassa, Yamina, Viaud, Magali, Arrom-Branas, Maria Beatriz, Boddaert, Nathalie, Puget, Stéphanie, Blauwblomme, Thomas, Alapetite, Claire, Bolle, Stéphanie, Doz, François, Grill, Jacques, Dufour, Christelle, Bourdeaut, Franck, Abbou, Samuel, Guerrini-Rousseau, Léa, Leruste, Amaury, Beccaria, Kévin, Polak, Michel, Kariyawasam, Dulanjalee

“…Adamantinomatous craniopharyngioma mainly affects children. Excessive weight gain is a major long-term complication. The primary objective of this study was to…”
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Role of neoadjuvant chemotherapy in metastatic medulloblastoma: a comparative study in 92 children by Guerrini-Rousseau, Léa, Abbas, Rachid, Huybrechts, Sophie, Kieffer-Renaux, Virginie, Puget, Stéphanie, Andreiuolo, Felipe, Beccaria, Kévin, Blauwblomme, Thomas, Bolle, Stéphanie, Dhermain, Frédéric, Longaud Valès, Audrey, Roujeau, Thomas, Sainte-Rose, Christian, Tauziede-Espariat, Arnault, Varlet, Pascale, Zerah, Michel, Valteau-Couanet, Dominique, Dufour, Christelle, Grill, Jacques

“…Abstract Background Previous pilot studies have shown the feasibility of preoperative chemotherapy in patients with medulloblastoma, but benefits and risks…”
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