Search Results - "Kettyle, L. M."

HOXA/PBX3 knockdown impairs growth and sensitizes cytogenetically normal acute myeloid leukemia cells to chemotherapy by Dickson, G. J., Liberante, F. G., Kettyle, L. M., O'Hagan, K. A., Finnegan, D. P. J., Bullinger, L., Geerts, D., McMullin, M. F., Lappin, T. R. J., Mills, K. I., Thompson, A.

“…The cytogenetically normal subtype of acute myeloid leukemia is associated with an intermediate risk which complicates therapeutic options. Lower overall…”
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Hierarchically related lineage-restricted fates of multipotent haematopoietic stem cells by Carrelha, Joana, Meng, Yiran, Kettyle, Laura M., Luis, Tiago C., Norfo, Ruggiero, Alcolea, Verónica, Boukarabila, Hanane, Grasso, Francesca, Gambardella, Adriana, Grover, Amit, Högstrand, Kari, Lord, Allegra M., Sanjuan-Pla, Alejandra, Woll, Petter S., Nerlov, Claus, Jacobsen, Sten Eirik W.

“…Analysis of transplantation of single haematopoietic stem cells in mice defines stable lineage-restricted fates in long-term self-renewing multipotent stem…”
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Platelet and myeloid lineage biases of transplanted single perinatal mouse hematopoietic stem cells by Belander Strålin, Karin, Carrelha, Joana, Winroth, Axel, Ziegenhain, Christoph, Hagemann-Jensen, Michael, Kettyle, Laura M., Hillen, Amy, Högstrand, Kari, Markljung, Ellen, Grasso, Francesca, Seki, Masafumi, Mazzi, Stefania, Meng, Yiran, Wu, Bishan, Chari, Edwin, Lehander, Madeleine, Sandberg, Rickard, Woll, Petter S., Jacobsen, Sten Eirik W.

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Panhematopoietic RNA barcoding enables kinetic measurements of nucleate and anucleate lineages and the activation of myeloid clones following acute platelet depletion by Wojtowicz, Edyta E, Mistry, Jayna J, Uzun, Vladimir, Hellmich, Charlotte, Scoones, Anita, Chin, Desmond W, Kettyle, Laura M, Grasso, Francesca, Lord, Allegra M, Wright, David J, Etherington, Graham J, Woll, Petter S, Belderbos, Mirjam E, Bowles, Kristian M, Nerlov, Claus, Haerty, Wilfried, Bystrykh, Leonid V, Jacobsen, Sten Eirik W, Rushworth, Stuart A, Macaulay, Iain C

“…Platelets and erythrocytes constitute over 95% of all hematopoietic stem cell output. However, the clonal dynamics of HSC contribution to these lineages…”
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