Search Results - "Kettelhut, Ísis C."

Interleukin-1 receptor-induced PGE2 production controls acetylcholine-mediated cardiac dysfunction and mortality during scorpion envenomation by Reis, Mouzarllem B., Rodrigues, Fernanda L., Lautherbach, Natalia, Kanashiro, Alexandre, Sorgi, Carlos A., Meirelles, Alyne F. G., Silva, Carlos A. A., Zoccal, Karina F., Souza, Camila O. S., Ramos, Simone G., Matsuno, Alessandra K., Rocha, Lenaldo B., Salgado, Helio C., Navegantes, Luiz C. C., Kettelhut, Ísis C., Cupo, Palmira, Gardinassi, Luiz G., Faccioli, Lúcia H.

“…Scorpion envenomation is a leading cause of morbidity and mortality among accidents caused by venomous animals. Major clinical manifestations that precede…”
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Acute intermittent hypoxia in rats activates muscle proteolytic pathways through a gluccorticoid-dependent mechanism by Przygodda, Franciele, Manfredi, Leandro Henrique, Machado, Juliano, Gonçalves, Dawit A P, Zanon, Neusa M, Bonagamba, Leni G H, Machado, Benedito H, Kettelhut, Ísis C, Navegantes, Luiz C C

“…Although it is well known that chronic hypoxia induces muscle wasting, the effects of intermittent hypoxia on skeletal muscle protein metabolism remain…”
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Alterations of cAMP-dependent signaling in dystrophic skeletal muscle by Rudolf, Rüdiger, Khan, Muzamil M, Lustrino, Danilo, Labeit, Siegfried, Kettelhut, Isis C, Navegantes, Luiz C C

“…Autonomic regulation processes in striated muscles are largely mediated by cAMP/PKA-signaling. In order to achieve specificity of signaling its…”
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Sympathetic innervation controls homeostasis of neuromuscular junctions in health and disease by Khan, Muzamil Majid, Lustrino, Danilo, Silveira, Willian A., Wild, Franziska, Straka, Tatjana, Issop, Yasmin, O’Connor, Emily, Cox, Dan, Reischl, Markus, Marquardt, Till, Labeit, Dittmar, Labeit, Siegfried, Benoit, Evelyne, Molgó, Jordi, Lochmüller, Hanns, Witzemann, Veit, Kettelhut, Isis C., Navegantes, Luiz C. C., Pozzan, Tullio, Rudolf, Rüdiger

“…The distribution and function of sympathetic innervation in skeletal muscle have largely remained elusive. Here we demonstrate that sympathetic neurons make…”
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Role of adrenoceptors and cAMP on the catecholamine-induced inhibition of proteolysis in rat skeletal muscle by Navegantes, L C, Resano, N M, Migliorini, R H, Kettelhut, I C

“…The role of adrenoceptor subtypes and of cAMP on rat skeletal muscle proteolysis was investigated using a preparation that maintains tissue glycogen stores and…”
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Maternal Vitamin D Deficiency Impairs the Development of β Cells in Offspring Rats in a Sex-Dependent Manner by Schavinski, Aline Z, Reis, Natany G, Morgan, Henrique J N, Assis, Ana Paula, Moro, Matheus L, Valentim, Rafael R, Seni-Silva, Ana Carolina, Ramos, Ester S, Kettelhut, Isis C, Navegantes, Luiz C C

“…Recent studies have shown that maternal vitamin D deficiency (VDD) causes long-term metabolic changes in offspring. However, little is known about the impact…”
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β2-Adrenoceptors activation regulates muscle trophic-related genes following acute resistance exercise in mice by Abdalla-Silva, Ronaldo L., Zanetti, Gustavo O., Lautherbach, Natalia, Schavinski, Aline Zanatta, Heck, Lilian C., Gonçalves, Dawit A. P., Kettelhut, Isis C., Navegantes, Luiz C. C., Silveira, Wilian A.

“…Resistance exercise (RE) training and pharmacological stimulation of β 2 -Adrenoceptors (β 2 -ARs) alone can promote muscle hypertrophy and prevent muscle…”
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Insulin/IGF1 signalling mediates the effects of β2‐adrenergic agonist on muscle proteostasis and growth by Gonçalves, Dawit A., Silveira, Wilian A., Manfredi, Leandro H., Graça, Flávia A., Armani, Andrea, Bertaggia, Enrico, O´Neill, Brian T., Lautherbach, Natalia, Machado, Juliano, Nogara, Leonardo, Pereira, Marcelo G., Arcidiacono, Diletta, Realdon, Stefano, Kahn, C. Ronald, Sandri, Marco, Kettelhut, Isis C., Navegantes, Luiz Carlos C.

“…Background Stimulation of β2‐adrenoceptors can promote muscle hypertrophy and fibre type shift, and it can counteract atrophy and weakness. The underlying…”
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Clenbuterol suppresses proteasomal and lysosomal proteolysis and atrophy-related genes in denervated rat soleus muscles independently of Akt by Gonçalves, Dawit A P, Silveira, Wilian A, Lira, Eduardo C, Graça, Flávia A, Paula-Gomes, Silvia, Zanon, Neusa M, Kettelhut, Isis C, Navegantes, Luiz C C

“…Although it is well known that administration of the selective β(2)-adrenergic agonist clenbuterol (CB) protects muscle following denervation (DEN), the…”
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Triacsin C reduces lipid droplet formation and induces mitochondrial biogenesis in primary rat hepatocytes by Dechandt, Carlos R. P., Zuccolotto-dos-Reis, Felippe H., Teodoro, Bruno G., Fernandes, Anna Maria A. P., Eberlin, Marcos N., Kettelhut, Isis C., Curti, Carlos, Alberici, Luciane C.

“…Intracellular long-chain acyl-CoA synthetases (ACSL) activate fatty acids to produce acyl-CoA, which undergoes β-oxidation and participates in the synthesis of…”
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Urocortin 2 promotes hypertrophy and enhances skeletal muscle function through cAMP and insulin/IGF-1 signaling pathways by Lautherbach, Natalia, Gonçalves, Dawit A.P., Silveira, Wilian A., Paula-Gomes, Sílvia, Valentim, Rafael Rossi, Zanon, Neusa M., Pereira, Marcelo G., Miyabara, Elen H., Navegantes, Luiz C.C., Kettelhut, Isis C.

“…Although it is well established that urocortin 2 (Ucn2), a peptide member of the corticotrophin releasing factor (CRF) family, and its specific…”
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Maternal vitamin D deficiency affects the morphology and function of glycolytic muscle in adult offspring rats by Reis, Natany G., Assis, Ana P., Lautherbach, Natália, Gonçalves, Dawit A., Silveira, Wilian A., Morgan, Henrique J.N., Valentim, Rafael R., Almeida, Lucas F., Heck, Lilian C., Zanon, Neusa M., Koike, Tatiana E., Santos, Audrei R., Miyabara, Elen H., Kettelhut, Isis C., Navegantes, Luiz C.

“…Background Fetal stage is a critical developmental window for the skeletal muscle, but little information is available about the impact of maternal vitamin D…”
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α−Calcitonin gene-related peptide inhibits autophagy and calpain systems and maintains the stability of neuromuscular junction in denervated muscles by Machado, Juliano, Silveira, Wilian A., Gonçalves, Dawit A., Schavinski, Aline Zanatta, Khan, Muzamil M., Zanon, Neusa M., Diaz, Mauricio Berriel, Rudolf, Rüdiger, Kettelhut, Isis C., Navegantes, Luiz C.

“…Although it is well established that a-calcitonin gene-related peptide (CGRP) stabilizes muscle-type cholinergic receptors nicotinic subunits (AChR), the…”
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A Low-Protein, High-Carbohydrate Diet Increases Fatty Acid Uptake and Reduces Norepinephrine-Induced Lipolysis in Rat Retroperitoneal White Adipose Tissue by dos Santos, Maísa P., de França, Suélem A., dos Santos, José Tiago F., Buzelle, Samyra L., Bertolini, Gisele L., Garófalo, Maria Antonieta R., do Kettelhut, Isis C., Frasson, Danúbia, Chaves, Valéria E., Kawashita, Nair H.

“…A low-protein, high-carbohydrate (LPHC) diet for 15 days increased the lipid content in the carcass and adipose tissues of rats. The aim of this work was to…”
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Leucine supplementation accelerates connective tissue repair of injured tibialis anterior muscle by Pereira, Marcelo G, Silva, Meiricris T, Carlassara, Eduardo O C, Gonçalves, Dawit A, Abrahamsohn, Paulo A, Kettelhut, Isis C, Moriscot, Anselmo S, Aoki, Marcelo S, Miyabara, Elen H

“…This study investigated the effect of leucine supplementation on the skeletal muscle regenerative process, focusing on the remodeling of connective tissue of…”
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Mechanisms Involved in 3′,5′-Cyclic Adenosine Monophosphate-Mediated Inhibition of the Ubiquitin-Proteasome System in Skeletal Muscle by Gonçalves, Dawit A. P, Lira, Eduardo C, Baviera, Amanda M, Cao, Peirang, Zanon, Neusa M, Arany, Zoltan, Bedard, Nathalie, Tanksale, Preeti, Wing, Simon S, Lecker, Stewart H, Kettelhut, Isis C, Navegantes, Luiz C. C

“…Although it is well known that catecholamines inhibit skeletal muscle protein degradation, the molecular underlying mechanism remains unclear. This study was…”
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Lipolytic response of adipose tissue and metabolic adaptations to long periods of fasting in red tilapia (Oreochromis sp., Teleostei: Cichlidae) by Dias, Junior, Walter, Baviera, Amanda M, Zanon, Neusa M, Galban, Victor D, Garófalo, Maria Antonieta R, Machado, Celio R, Bailão, Elisa F L C, Kettelhut, Isis C

“…Adaptive changes of carbohydrate and lipid metabolism induced by 7, 15, 30, 60, 90, 150 and 200 days of fasting were investigated in red tilapia (Oreochromis…”
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Sympathetic innervation in skeletal muscle and its role at the neuromuscular junction by Rudolf, Rüdiger, Kettelhut, Isis C., Navegantes, Luiz Carlos C.

“…Neuromuscular junctions are the synapses between motor neurons and skeletal muscle fibers, which mediate voluntary muscle movement. Since neuromuscular…”
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cAMP‐dependent protein kinase inhibits FoxO activity and regulates skeletal muscle plasticity in mice by Silveira, Wilian A., Gonçalves, Dawit A., Machado, Juliano, Lautherbach, Natalia, Lustrino, Danilo, Paula‐Gomes, Silvia, Pereira, Marcelo G., Miyabara, Elen H., Sandri, Marco, Kettelhut, Isis C., Navegantes, Luiz C.

“…Although we have shown that catecholamines suppress the activity of the Ubiquitin‐Proteasome System (UPS) and atrophy‐related genes expression through a…”
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Calcitonin gene-related peptide exerts inhibitory effects on autophagy in the heart of mice by Schavinski, Aline Zanatta, Machado, Juliano, Morgan, Henrique Jorge Novaes, Lautherbach, Natalia, Paula-Gomes, Silvia, Kettelhut, Isis C., Navegantes, Luiz Carlos C.

“…•CGRP in vivo acutely inhibits autophagy in the heart of fed and fasted mice.•CGRP in vivo reduces insulinemia and increases glycemia.•CGRP activates PKA/CREB…”
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