Search Results - "Ketheesan, Natkunam"

Immunological mechanisms contributing to the double burden of diabetes and intracellular bacterial infections by Hodgson, Kelly, Morris, Jodie, Bridson, Tahnee, Govan, Brenda, Rush, Catherine, Ketheesan, Natkunam

“…Summary Diabetes has been recognized as an important risk factor for a variety of intracellular bacterial infections, but research into the dysregulated immune…”
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Microbiology at Home (M@H): an Online, Self-Paced Solution To Enhance Practical Skills in Foundation Microbiology by Winter, Gal, Ketheesan, Natkunam

“…The online education market share is rapidly increasing, raising the demand to teach sciences outside the laboratory environment. Here, we present Microbiology…”
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The Burkholderia pseudomallei intracellular ‘TRANSITome’ by Heacock-Kang, Yun, McMillan, Ian A., Norris, Michael H., Sun, Zhenxin, Zarzycki-Siek, Jan, Bluhm, Andrew P., Cabanas, Darlene, Norton, Robert E., Ketheesan, Natkunam, Miller, Jeff F., Schweizer, Herbert P., Hoang, Tung T.

“…Prokaryotic cell transcriptomics has been limited to mixed or sub-population dynamics and individual cells within heterogeneous populations, which has hampered…”
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A new hub-and-spoke biology curriculum designed around interdisciplinary laboratory practical sessions to enhance student employability by Winter, Gal, Ketheesan, Natkunam, Andronicos, Nicholas M.

“…A new hub-and-spoke (H&S) model for restructuring the traditional biological science curriculum is presented here. The H&S model emphasises the integration of…”
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Enhancing Checkpoint Inhibitor Therapy in Solid Tissue Cancers: The Role of Diet, the Microbiome & Microbiome-Derived Metabolites by Malczewski, Agnieszka Beata, Ketheesan, Natkunam, Coward, Jermaine I G, Navarro, Severine

“…Host immunity plays a central role in the regulation of anti-tumour responses during checkpoint inhibitor therapy (CIT). The mechanisms involved in long…”
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Defects in early cell recruitment contribute to the increased susceptibility to respiratory Klebsiella pneumoniae infection in diabetic mice by Martinez, Nuria, Ketheesan, Natkunam, Martens, Gregory W., West, Kim, Lien, Egil, Kornfeld, Hardy

“…Diabetes is associated with increased susceptibility to Klebsiella pneumoniae and poor prognosis with infection. We demonstrate accelerated mortality in mice…”
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Microbiome-derived metabolome as a potential predictor of response to cancer immunotherapy by Malczewski, Agnieszka Beata, Navarro, Severine, Coward, Jermaine IG, Ketheesan, Natkunam

“…Cancer immunotherapy with checkpoint blockade has become standard of care treatment for numerous cancer types. Despite this, robust predictive biomarkers are…”
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The role of anti-myosin antibodies in perpetuating cardiac damage following myocardial infarction by O'Donohoe, Tom J, Schrale, Ryan G, Ketheesan, Natkunam

“…Abstract Recent improvements in the medical and surgical management of myocardial infarction mean that many patients are now surviving with greater impairment…”
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Streptococcus pyogenes vaccine candidates do not induce autoimmune responses in a rheumatic heart disease model by Reynolds, Simone, Rafeek, Rukshan Ahamed Mohamed, Hamlin, Adam, Lepletier, Ailin, Pandey, Manisha, Ketheesan, Natkunam, Good, Michael F.

“…We have developed a candidate vaccine to protect against multiple strains of Streptococcus pyogenes infections. The candidate vaccine contains two synthetic…”
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B- and T-Cell Responses in Group A Streptococcus M-Protein- or Peptide-Induced Experimental Carditis by Gorton, Davina, Govan, Brenda, Olive, Colleen, Ketheesan, Natkunam

“…The etiology of rheumatic fever and rheumatic heart disease (RF/RHD) is believed to be autoimmune, involving immune responses initiated between streptococcal…”
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BCG Vaccination Prevents Reactivation of Latent Lymphatic Murine Tuberculosis Independently of CD4 + T Cells by Sathkumara, Harindra D, Pai, Saparna, Aceves-Sánchez, Michel de Jesús, Ketheesan, Natkunam, Flores-Valdez, Mario Alberto, Kupz, Andreas

“…Tuberculosis (TB) is a major global public health problem causing significant mortality and morbidity. In addition to ~10.4 million cases of active TB…”
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Increased Neurotropic Threat from Burkholderia pseudomallei Strains with a B. mallei-like Variation in the bimA Motility Gene, Australia by Morris, Jodie L, Fane, Anne, Sarovich, Derek S, Price, Erin P, Rush, Catherine M, Govan, Brenda L, Parker, Elizabeth, Mayo, Mark, Currie, Bart J, Ketheesan, Natkunam

“…Neurologic melioidosis is a serious, potentially fatal form of Burkholderia pseudomallei infection. Recently, we reported that a subset of clinical isolates of…”
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Anti-troponin antibodies following myocardial infarction by O’Donohoe, Tom J., MBBS, Ketheesan, Natkunam, MD, PhD, Schrale, Ryan G., MBBS, MSc, FRACP, FCSANZ

“…Abstract Recent improvements in medical and surgical coronary revascularization techniques have significantly improved outcomes for patients with acute…”
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Impaired Early Cytokine Responses at the Site of Infection in a Murine Model of Type 2 Diabetes and Melioidosis Comorbidity by Hodgson, Kelly A, Govan, Brenda L, Walduck, Anna K, Ketheesan, Natkunam, Morris, Jodie L

“…Classifications Services IAI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Group A streptococcal M-protein specific antibodies and T-cells drive the pathology observed in the rat autoimmune valvulitis model by Sikder, Suchandan, Price, Georgina, Alim, Md Abdul, Gautam, Anil, Scott Simpson, Robert, Margaret Rush, Catherine, Lee Govan, Brenda, Ketheesan, Natkunam

“…Acute rheumatic fever (ARF) and rheumatic heart disease (RHD) are autoimmune mediated diseases triggered by group A streptococcal (GAS) infections. Molecular…”
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Neurobehavioral Changes Associated with Rheumatic Fever and Rheumatic Heart Disease: A Narrative Review by McMillan, David, Ketheesan, Sarangan, Rafeek, Rukshan Ahamed Mohamed, Thapa, Riya, Munif, Mohammad Raguib, Hamlin, Adam, Tully, Phillip, Norton, Robert, White, Andrew, Ketheesan, Natkunam

“…Acute rheumatic fever (ARF) and rheumatic heart disease (RHD) are autoimmune conditions triggered by Group A Streptococcus skin or throat infections. If…”
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Burkholderia pseudomallei Triggers Altered Inflammatory Profiles in a Whole-Blood Model of Type 2 Diabetes-Melioidosis Comorbidity by MORRIS, Jodie, WILLIAMS, Natasha, RUSH, Catherine, GOVAN, Brenda, SANGLA, Kunwarjit, NORTON, Robert, KETHEESAN, Natkunam

“…Classifications Services IAI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Research Ready: a student-initiated workshop model for developing foundational research skills by Sivarajah, Nivetha, Irranious, Jenevan A, Krishnamoorthy, Sivagini, Kalaineethan, Thayaparan, Kugathasan, Deluxeani, Sivanantham, Uventhikka, McMillan, Mary E, Ketheesan, Natkunam

“…Travel restrictions, pandemics, economic downturn, and increasing costs in organizing workshops all impact on face-to-face training of undergraduates planning…”
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Requirements for a Robust Animal Model to Investigate the Disease Mechanism of Autoimmune Complications Associated With ARF/RHD by Rafeek, Rukshan A M, Sikder, Suchandan, Hamlin, Adam S, Andronicos, Nicholas M, McMillan, David J, Sriprakash, Kadaba S, Ketheesan, Natkunam

“…The pathogenesis of Acute Rheumatic Fever/Rheumatic Heart Disease (ARF/RHD) and associated neurobehavioral complications including Sydenham's chorea (SC) is…”
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Neurotropic threat characterization of Burkholderia pseudomallei strains by Morris, Jodie, Fane, Anne, Rush, Catherine, Govan, Brenda, Mayo, Mark, Currie, Bart J, Ketheesan, Natkunam

“…The death rate for neurologic melioidosis is high. Whether certain Burkholderia pseudomallei strains are more likely than other strains to cause central…”
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