Search Results - "Kesteloot, F"
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ADAMTS-2 functions as anti-angiogenic and anti-tumoral molecule independently of its catalytic activity
Published in Cellular and molecular life sciences : CMLS (01-12-2010)“…ADAMTS-2 is a metalloproteinase that plays a key role in the processing of fibrillar procollagen precursors into mature collagen molecules by excising the…”
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Domains and Maturation Processes That Regulate the Activity of ADAMTS-2, a Metalloproteinase Cleaving the Aminopropeptide of Fibrillar Procollagens Types I–III and V
Published in The Journal of biological chemistry (14-10-2005)“…Processing of fibrillar collagens is required to generate collagen monomers able to self-assemble into elongated and cylindrical collagen fibrils. ADAMTS-2…”
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Regulation of procollagen amino-propeptide processing during mouse embryogenesis by specialization of homologous ADAMTS proteases: insights on collagen biosynthesis and dermatosparaxis
Published in Development (Cambridge) (15-04-2006)“…Mutations in ADAMTS2, a procollagen amino-propeptidase, cause severe skin fragility, designated as dermatosparaxis in animals, and a subtype of the…”
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