Search Results - "Kessler, Catherine B"

miR-29 suppression of osteonectin in osteoblasts: Regulation during differentiation and by canonical Wnt signaling by Kapinas, Kristina, Kessler, Catherine B., Delany, Anne M.

“…The matricellular protein osteonectin, secreted protein acidic and rich in cysteine (SPARC, BM‐40), is the most abundant non‐collagenous matrix protein in…”
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Pathway analysis of microRNA expression profile during murine osteoclastogenesis by Franceschetti, Tiziana, Dole, Neha S, Kessler, Catherine B, Lee, Sun-Kyeong, Delany, Anne M

“…To design novel therapeutics against bone loss, understanding the molecular mechanisms regulating osteoclastogenesis is critical. Osteoclast formation and…”
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Bone matrix osteonectin limits prostate cancer cell growth and survival by Kapinas, Kristina, Lowther, Katie M., Kessler, Catherine B., Tilbury, Karissa, Lieberman, Jay R., Tirnauer, Jennifer S., Campagnola, Paul, Delany, Anne M.

“…There is considerable interest in understanding prostate cancer metastasis to bone and the interaction of these cells with the bone microenvironment…”
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miR-29 Promotes Murine Osteoclastogenesis by Regulating Osteoclast Commitment and Migration by Franceschetti, Tiziana, Kessler, Catherine B., Lee, Sun-Kyeong, Delany, Anne M.

“…Osteoclast differentiation is regulated by transcriptional, post-transcriptional, and post-translational mechanisms. MicroRNAs are fundamental…”
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Increased Notch 1 Expression and Attenuated Stimulatory G Protein Coupling to Adenylyl Cyclase in Osteonectin-Null Osteoblasts by Kessler, Catherine B, Delany, Anne M

“…Osteonectin, or secreted protein acidic and rich in cysteine, is one of the most abundant noncollagen matrix components in bone. This matricellular protein…”
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A Single Nucleotide Polymorphism in Osteonectin 3′ Untranslated Region Regulates Bone Volume and Is Targeted by miR‐433 by Dole, Neha S, Kapinas, Kristina, Kessler, Catherine B, Yee, Siu‐Pok, Adams, Douglas J, Pereira, Renata C, Delany, Anne M

“…ABSTRACT Osteonectin/SPARC is one of the most abundant noncollagenous extracellular matrix proteins in bone, regulating collagen fiber assembly and promoting…”
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IGF-I 3′ Untranslated Region: Strain-Specific Polymorphisms and Motifs Regulating IGF-I in Osteoblasts by Smith, Spenser S, Kessler, Catherine B, Shenoy, Vikram, Rosen, Clifford J, Delany, Anne M

“…Reduced IGF-I is associated with low bone mass in humans and mice. C3H/He/J (C3H) mice have higher skeletal IGF-I and greater bone mass than C57BL/6J (B6). We…”
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Accentuated osteoclastic response to parathyroid hormone undermines bone mass acquisition in osteonectin-null mice by Machado do Reis, Luciene, Kessler, Catherine B, Adams, Douglas J, Lorenzo, Joseph, Jorgetti, Vanda, Delany, Anne M

“…Abstract Matricellular proteins play a unique role in the skeleton as regulators of bone remodeling, and the matricellular protein osteonectin (SPARC, BM-40)…”
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