Search Results - "Kessler, Almuth F."

Changes of O6-Methylguanine DNA Methyltransferase (MGMT) Promoter Methylation in Glioblastoma Relapse—A Meta-Analysis Type Literature Review by Feldheim, Jonas, Kessler, Almuth F., Monoranu, Camelia M., Ernestus, Ralf-Ingo, Löhr, Mario, Hagemann, Carsten

“…Methylation of the O6-methylguanine DNA methyltransferase (MGMT) promoter has emerged as strong prognostic factor in the therapy of glioblastoma multiforme. It…”
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Effects of Long-Term Temozolomide Treatment on Glioblastoma and Astrocytoma WHO Grade 4 Stem-like Cells by Feldheim, Jonas, Kessler, Almuth F, Feldheim, Julia J, Schulz, Ellina, Wend, David, Lazaridis, Lazaros, Kleinschnitz, Christoph, Glas, Martin, Ernestus, Ralf-Ingo, Brandner, Sebastian, Monoranu, Camelia M, Löhr, Mario, Hagemann, Carsten

“…Glioblastoma leads to a fatal course within two years in more than two thirds of patients. An essential cornerstone of therapy is chemotherapy with…”
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Glioma patients in outpatient care-optimization of psychosocial care in neuro-oncological patients (GLIOPT): Protocol for a cluster randomized controlled trial by Renovanz, Mirjam, Hippler, Melina, Voss, Martin, Wehinger, Jens, Keßler, Almuth F, Gempt, Jens, Nadji-Ohl, Minou, Weiß Lucas, Carolin, Rapp, Marion, Misch, Martin, Coburger, Jan, Mehlitz, Marcus, Meixensberger, Jürgen, Keric, Naureen, Tabatabai, Ghazaleh, Blettner, Maria, Schranz, Melanie, Singer, Susanne

“…Patients with high-grade gliomas (HGG) often suffer from high distress and require psychosocial support. However, due to neurological and neurocognitive…”
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Tumor Treating Fields (TTFields) Induce Cell Junction Alterations in a Human 3D In Vitro Model of the Blood-Brain Barrier by Salvador, Ellaine, Köppl, Theresa, Hörmann, Julia, Schönhärl, Sebastian, Bugaeva, Polina, Kessler, Almuth F, Burek, Malgorzata, Ernestus, Ralf-Ingo, Löhr, Mario, Hagemann, Carsten

“…In a recent study, we showed in an in vitro murine cerebellar microvascular endothelial cell (cerebEND) model as well as in vivo in rats that Tumor-Treating…”
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Screening for symptom burden and supportive needs of patients with glioblastoma and brain metastases and their caregivers in relation to their use of specialized palliative care by Seekatz, Bettina, Lukasczik, Matthias, Löhr, Mario, Ehrmann, Katja, Schuler, Michael, Keßler, Almuth F., Neuderth, Silke, Ernestus, Ralf-Ingo, van Oorschot, Birgitt

“…Purpose Patients with brain tumors have a high symptom burden and multiple supportive needs. Needs of caregivers are often unattended. This study aims to…”
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Effects of the Selective MPS1 Inhibitor MPS1-IN-3 on Glioblastoma Sensitivity to Antimitotic Drugs by TANNOUS, Bakhos A, KERAMI, Mariam, LAGERWEIJ, Tonny, WEDEKIND, Laurine, NIERS, Johanna M, BARAZAS, Marco, NILSSON, R. Jonas A, GEERTS, Dirk, DE WITT HAMER, Philip C, HAGEMANN, Carsten, VANDERTOP, W. Peter, VAN TELLINGEN, Olaf, VAN DER STOOP, Petra M, NOSKE, David P, GRAY, Nathanael S, WÜRDINGER, Thomas, KWIATKOWSKI, Nicholas, JINHUA WANG, WENJUN ZHOU, KESSLER, Almuth F, LEWANDROWSKI, Grant, HIDDINGH, Lotte, SOL, Nik

“…Glioblastomas exhibit a high level of chemotherapeutic resistance, including to the antimitotic agents vincristine and taxol. During the mitotic agent-induced…”
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Identification of KIF11 As a Novel Target in Meningioma by Jungwirth, Gerhard, Yu, Tao, Moustafa, Mahmoud, Rapp, Carmen, Warta, Rolf, Jungk, Christine, Sahm, Felix, Dettling, Steffen, Zweckberger, Klaus, Lamszus, Katrin, Senft, Christian, Loehr, Mario, Keßler, Almuth F, Ketter, Ralf, Westphal, Manfred, Debus, Juergen, von Deimling, Andreas, Simon, Matthias, Unterberg, Andreas, Abdollahi, Amir, Herold-Mende, Christel

“…Kinesins play an important role in many physiological functions including intracellular vesicle transport and mitosis. The emerging role of kinesins in…”
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Tumor Treating Fields (TTFields) Reversibly Permeabilize the Blood–Brain Barrier In Vitro and In Vivo by Salvador, Ellaine, Kessler, Almuth F, Domröse, Dominik, Hörmann, Julia, Schaeffer, Clara, Giniunaite, Aiste, Burek, Malgorzata, Tempel-Brami, Catherine, Voloshin, Tali, Volodin, Alexandra, Zeidan, Adel, Giladi, Moshe, Ernestus, Ralf-Ingo, Löhr, Mario, Förster, Carola Y, Hagemann, Carsten

“…Despite the availability of numerous therapeutic substances that could potentially target CNS disorders, an inability of these agents to cross the restrictive…”
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Ribosomal Protein S27/Metallopanstimulin-1 (RPS27) in Glioma-A New Disease Biomarker? by Feldheim, Jonas, Kessler, Almuth F, Schmitt, Dominik, Salvador, Ellaine, Monoranu, Camelia M, Feldheim, Julia J, Ernestus, Ralf-Ingo, Löhr, Mario, Hagemann, Carsten

“…Despite its significant overexpression in several malignant neoplasms, the expression of RPS27 in the central nervous system (CNS) is widely unknown. We…”
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Imaging of Cerebral Arteriovenous Malformations and Arteriovenous Fistulas and Occlusion Control Using Intraoperative 3-Dimensional Rotational Fluoroscopy by Linsenmann, Thomas, Lilla, Nadine, Stetter, Christian, Keßler, Almuth F., Ernestus, Ralf-Ingo, Westermaier, Thomas

“…Intraoperative resection or occlusion control is indispensable in the surgery of vascular anomalies. This can be conducted using local vascular imaging…”
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Primary brain amyloidoma, both a neoplastic and a neurodegenerative disease: a case report by Löhr, Mario, Kessler, Almuth F, Monoranu, Camelia-Maria, Grosche, Jens, Linsenmann, Thomas, Ernestus, Ralf-Ingo, Härtig, Wolfgang

“…Scattered extracellular deposits of amyloid within the brain parenchyma can be found in a heterogeneous group of diseases. Its condensed accumulation in the…”
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Intraoperative Cerebral Angiography by Intravenous Contrast Administration With 3-Dimensional Rotational Fluoroscopy in Patients With Intracranial Aneurysms: A Feasibility Study by Westermaier, Thomas, Linsenmann, Thomas, Keler, Almuth F, Stetter, Christian, Willner, Nadine, Solymosi, Laszlo, Ernestus, Ralf-Ingo, Vince, Giles H

“…BACKGROUND:Intraoperative imaging of cerebral aneurysms may be desirable in emergency situations with large space-occupying hematomas or to visualize vessels…”
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[ 68 Ga]-Pentixafor PET/CT for CXCR4-Mediated Imaging of Vestibular Schwannomas by Breun, Maria, Monoranu, Camelia M, Kessler, Almuth F, Matthies, Cordula, Löhr, Mario, Hagemann, Carsten, Schirbel, Andreas, Rowe, Steven P, Pomper, Martin G, Buck, Andreas K, Wester, Hans-Jürgen, Ernestus, Ralf-Ingo, Lapa, Constantin

“…We have recently demonstrated CXCR4 overexpression in vestibular schwannomas (VS). This study investigated the feasibility of CXCR4-directed positron emission…”
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Monopolar Spindle 1 Kinase (MPS1/TTK) mRNA Expression is Associated with Earlier Development of Clinical Symptoms, Tumor Aggressiveness and Survival of Glioma Patients by Kessler, Almuth F., Feldheim, Jonas, Schmitt, Dominik, Feldheim, Julia J., Monoranu, Camelia M., Ernestus, Ralf-Ingo, Löhr, Mario, Hagemann, Carsten

“…Inhibition of the protein kinase MPS1, a mitotic spindle-checkpoint regulator, reinforces the effects of multiple therapies against glioblastoma multiforme…”
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Comparison of the amino acid tracers 18F-FET and 18F-DOPA in high-grade glioma patients by Lapa, Constantin, Linsenmann, Thomas, Monoranu, Camelia Maria, Samnick, Samuel, Buck, Andreas K, Bluemel, Christina, Czernin, Johannes, Kessler, Almuth F, Homola, Gyoergy A, Ernestus, Ralf-Ingo, Löhr, Mario, Herrmann, Ken

“…High-grade gliomas (HGGs) are the most common malignant primary tumors of the central nervous system. PET probes of amino acid transport such as…”
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O-(2-(18F)fluoroethyl)-L-tyrosine PET for the differentiation of tumour recurrence from late pseudoprogression in glioblastoma by Mihovilovic, Milena I, Kertels, Olivia, Hänscheid, Heribert, Löhr, Mario, Monoranu, Camelia-Maria, Kleinlein, Irene, Samnick, Samuel, Kessler, Almuth F, Linsenmann, Thomas, Ernestus, Ralf-Ingo, Buck, Andreas K, Lapa, Constantin

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(68)Ga-Pentixafor-PET/CT for Imaging of Chemokine Receptor 4 Expression in Glioblastoma by Lapa, Constantin, Lückerath, Katharina, Kleinlein, Irene, Monoranu, Camelia Maria, Linsenmann, Thomas, Kessler, Almuth F, Rudelius, Martina, Kropf, Saskia, Buck, Andreas K, Ernestus, Ralf-Ingo, Wester, Hans-Jürgen, Löhr, Mario, Herrmann, Ken

“…Chemokine receptor-4 (CXCR4) has been reported to be overexpressed in glioblastoma (GBM) and to be associated with poor survival. This study investigated the…”
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Cytotoxic T Cells and their Activation Status are Independent Prognostic Markers in Meningiomas by Rapp, Carmen, Dettling, Steffen, Liu, Fang, Ull, Anna Theresa, Warta, Rolf, Jungk, Christine, Roesch, Saskia, Mock, Andreas, Sahm, Felix, Schmidt, Melissa, Jungwirth, Gerhard, Zweckberger, Klaus, Lamszus, Katrin, Gousias, Konstaninos, Kessler, Almuth F, Grabe, Niels, Loehr, Mario, Ketter, Ralf, Urbschat, Steffi, Senft, Christian, Westphal, Manfred, Abdollahi, Amir, Debus, Juergen, von Deimling, Andreas, Unterberg, Andreas, Simon, Matthias, Herold-Mende, Christel C

“…Clinically aggressive meningiomas (MGMs) are rare but treatment-resistant tumors in need for more effective therapies. Because tumor-infiltrating T lymphocytes…”
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Glioblastoma-Derived Three-Dimensional Ex Vivo Models to Evaluate Effects and Efficacy of Tumor Treating Fields (TTFields) by Nickl, Vera, Schulz, Ellina, Salvador, Ellaine, Trautmann, Laureen, Diener, Leopold, Kessler, Almuth F, Monoranu, Camelia M, Dehghani, Faramarz, Ernestus, Ralf-Ingo, Löhr, Mario, Hagemann, Carsten

“…Glioblastoma (GBM) displays a wide range of inter- and intra-tumoral heterogeneity contributing to therapeutic resistance and relapse. Although Tumor Treating…”
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68Ga-Pentixafor-PET/CT for Imaging of Chemokine Receptor 4 Expression in Glioblastoma by Lapa, Constantin, Lückerath, Katharina, Kleinlein, Irene, Monoranu, Camelia Maria, Linsenmann, Thomas, Kessler, Almuth F., Rudelius, Martina, Kropf, Saskia, Buck, Andreas K., Ernestus, Ralf-Ingo, Wester, Hans-Jürgen, Löhr, Mario, Herrmann, Ken

“…Chemokine receptor-4 (CXCR4) has been reported to be overexpressed in glioblastoma (GBM) and to be associated with poor survival. This study investigated the…”
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