Search Results - "Kessel, Christoph"

Phagocyte-derived S100 proteins in autoinflammation: Putative role in pathogenesis and usefulness as biomarkers by Kessel, Christoph, Holzinger, Dirk, Foell, Dirk

“…Abstract The cytoplasmic S100 proteins derived from cells of myeloid origin are promising new markers of (auto-)inflammation. S100A8/A9 and S100A12 are…”
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Treatment of systemic juvenile idiopathic arthritis by Hinze, Claas H., Foell, Dirk, Kessel, Christoph

“…Systemic juvenile idiopathic arthritis (sJIA) is an inflammatory disease with hallmarks of severe systemic inflammation, which can be accompanied by arthritis…”
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Serum biomarkers confirming stable remission in inflammatory bowel disease by Kessel, Christoph, Lavric, Miha, Weinhage, Toni, Brueckner, Markus, de Roock, Sytze, Däbritz, Jan, Weber, Jakob, Vastert, Sebastiaan J., Foell, Dirk

“…Crohn's disease (CD) and ulcerative colitis (UC) have a chronic-remittent course. Optimal management of inflammatory bowel diseases (IBD) relies on early…”
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Discrimination of COVID‐19 From Inflammation‐Induced Cytokine Storm Syndromes Using Disease‐Related Blood Biomarkers by Kessel, Christoph, Vollenberg, Richard, Masjosthusmann, Katja, Hinze, Claas, Wittkowski, Helmut, Debaugnies, France, Nagant, Carole, Corazza, Francis, Vély, Frédéric, Kaplanski, Gilles, Girard‐Guyonvarc’h, Charlotte, Gabay, Cem, Schmidt, Hartmut, Foell, Dirk, Tepasse, Phil‐Robin

“…Objective Infection with the novel coronavirus SARS–CoV‐2 triggers severe illness with high mortality in a subgroup of patients. Such a critical course of…”
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Application of systems biology-based in silico tools to optimize treatment strategy identification in Still's disease by Segú-Vergés, Cristina, Coma, Mireia, Kessel, Christoph, Smeets, Serge, Foell, Dirk, Aldea, Anna

“…Systemic juvenile idiopathic arthritis (sJIA) and adult-onset Still's disease (AOSD) are manifestations of an autoinflammatory disorder with complex…”
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Genetic and environmental determinants for disease risk in subsets of rheumatoid arthritis defined by the anticitrullinated protein/peptide antibody fine specificity profile by Lundberg, Karin, Bengtsson, Camilla, Kharlamova, Nastya, Reed, Evan, Jiang, Xia, Kallberg, Henrik, Pollak-Dorocic, Iskra, Israelsson, Lena, Kessel, Christoph, Padyukov, Leonid, Holmdahl, Rikard, Alfredsson, Lars, Klareskog, Lars

“…To increase understanding of the aetiology and pathogenesis of rheumatoid arthritis (RA), genetic and environmental risk factors for RA subsets, defined by the…”
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Proinflammatory S100A12 Can Activate Human Monocytes via Toll-like Receptor 4 by FOELL, Dirk, WITTKOWSKI, Helmut, VAN ZOELEN, Marieke A. D, GOHAR, Faekah, SRIKRISHNA, Geetha, KRAFT, Matthias, ROTH, Johannes, KESSEL, Christoph, LÜKEN, Aloys, WEINHAGE, Toni, VARGA, Georg, VOGL, Thomas, WIRTH, Timo, VIEMANN, Dorothee, BJÖRK, Per

“…S100A12 is overexpressed during inflammation and is a marker of inflammatory disease. Furthermore, it has been ascribed to the group of damage-associated…”
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Vitamin D deficiency is associated with higher disease activity and the risk for uveitis in juvenile idiopathic arthritis - data from a German inception cohort by Sengler, Claudia, Zink, Julian, Klotsche, Jens, Niewerth, Martina, Liedmann, Ina, Horneff, Gerd, Kessel, Christoph, Ganser, Gerd, Thon, Angelika, Haas, Johannes-Peter, Hospach, Anton, Weller-Heinemann, Frank, Heiligenhaus, Arnd, Foell, Dirk, Zink, Angela, Minden, Kirsten

“…The objective was to evaluate the 25(OH) vitamin D (25(OH)D) status of patients with juvenile idiopathic arthritis (JIA) and determine whether the 25(OH)D…”
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Gene-Dose Effect of MEFV Gain-of-Function Mutations Determines ex vivo Neutrophil Activation in Familial Mediterranean Fever by Stoler, Iris, Freytag, Judith, Orak, Banu, Unterwalder, Nadine, Henning, Stephan, Heim, Katrin, von Bernuth, Horst, Krüger, Renate, Winkler, Stefan, Eschenhagen, Patience, Seipelt, Eva, Mall, Marcus A, Foell, Dirk, Kessel, Christoph, Wittkowski, Helmut, Kallinich, Tilmann

“…Familial Mediterranean fever (FMF) is caused by mutations within the Mediterranean fever ( ) gene. Disease severity depends on genotype and gene dose with most…”
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Optimizing supply and timing of nitrogen application for subirrigated potted chrysanthemums by Shelp, Barry J, Solntseva, Irina, Sutton, William J, Lum, Geoffrey B, Kessel, Christoph W

“…Two disbudded, potted chrysanthemum cultivars were subirrigated with 9.25, 12.3, and 18.5 mM N during vegetative, but not reproductive growth. At commercial…”
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Trajectories of disease courses in the inception cohort of newly diagnosed patients with JIA (ICON-JIA): the potential of serum biomarkers at baseline by Ganeva, Margarita, Fuehner, Sabrina, Kessel, Christoph, Klotsche, Jens, Niewerth, Martina, Minden, Kirsten, Foell, Dirk, Hinze, Claas H, Wittkowski, Helmut

“…Juvenile idiopathic arthritis (JIA) is a heterogeneous group of inflammatory joint disorders with a chronic-remitting disease course. Treat-to-target…”
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Antibodies to citrullinated proteins: molecular interactions and arthritogenicity by Uysal, Hüseyin, Nandakumar, Kutty Selva, Kessel, Christoph, Haag, Sabrina, Carlsen, Stefan, Burkhardt, Harald, Holmdahl, Rikard

“…The discovery of antibodies specific for citrullinated protein epitopes [anti-citrullinated protein antibodies (ACPAs)] is a hallmark for the diagnosis and…”
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Patients with Systemic Juvenile Idiopathic Arthritis (SJIA) Show Differences in Autoantibody Signatures Based on Disease Activity by Krainer, Julie, Hendling, Michaela, Siebenhandl, Sandra, Fuehner, Sabrina, Kessel, Christoph, Verweyen, Emely, Vierlinger, Klemens, Foell, Dirk, Schönthaler, Silvia, Weinhäusel, Andreas

“…Systemic juvenile idiopathic arthritis (SJIA) is a severe rheumatic disease in children. It is a subgroup of juvenile idiopathic arthritis (JIA; MIM #604302),…”
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A novel serum calprotectin (MRP8/14) particle-enhanced immuno-turbidimetric assay (sCAL turbo) helps to differentiate systemic juvenile idiopathic arthritis from other diseases in routine clinical laboratory settings by Foell, Dirk, Saers, Melanie, Park, Carolin, Brix, Ninna, Glerup, Mia, Kessel, Christoph, Wittkowski, Helmut, Hinze, Claas, Berntson, Lillemor, Fasth, Anders, Myrup, Charlotte, Nordal, Ellen, Rygg, Marite, Hasle, Henrik, Albertsen, Birgitte Klug, Herlin, Troels, Holzinger, Dirk, Niederberger, Christian, Schlüter, Bernhard

“…Background Differential diagnosis in children with signs of unprovoked inflammation can be challenging. In particular, differentiating systemic juvenile…”
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Type 1 Interferon‐Stimulated Gene Expression and Disease Activity in Pediatric Rheumatic Diseases: No Composite Scores Needed? by Weiden, Christina, Saers, Melanie, Schwarz, Tobias, Hinze, Tanja, Wittkowski, Helmut, Kessel, Christoph, Masjosthusmann, Katja, Mohr, Michael, Evers, Georg, Oesingmann‐Weirich, Sandra, Foell, Dirk, Hinze, Claas H.

“…Objective Rheumatic diseases are characterized by different patterns of immune overactivation. This study investigated the correlation of whole blood type 1…”
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Inflammatory biomarkers predicting long-term remission and active disease in juvenile idiopathic arthritis: a population-based study of the Nordic JIA cohort by Glerup, Mia, Kessel, Christoph, Foell, Dirk, Berntson, Lillemor, Fasth, Anders, Myrup, Charlotte, Nordal, Ellen, Rypdal, Veronika, Rygg, Marite, Arnstad, Ellen Dalen, Peltoniemi, Suvi, Aalto, Kristiina, Schleifenbaum, Susanne, Høllsberg, Malene Noer, Bilgrau, Anders Ellern, Herlin, Troels

“…ObjectivesTo assess the ability of baseline serum biomarkers to predict disease activity and remission status in juvenile idiopathic arthritis (JIA) at 18-year…”
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Approaches to SARS-CoV-2 and other vaccinations in children with a history of multisystem inflammatory syndrome (MIS-C): An international survey by Minoia, Francesca, Lucioni, Federica, Heshin-Bekenstein, Merav, Vastert, Sebastiaan, Kessel, Christoph, Uziel, Yosef, Lamot, Lovro, Ruperto, Nicolino, Gattorno, Marco, Bracaglia, Claudia, Toplak, Natasa

“…Background Following the Coronavirus Disease-19 (COVID-19) pandemic outbreaks, the hyperinflammatory condition termed Multisystem Inflammatory Syndrome in…”
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Calcium and zinc tune autoinflammatory Toll-like receptor 4 signaling by S100A12 by Kessel, Christoph, Fuehner, Sabrina, Zell, Jana, Zimmermann, Bastian, Drewianka, Stephan, Brockmeyer, Sonja, Holzinger, Dirk, Hinze, Claas, Wittkowski, Helmut, Foell, Dirk

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Autoantibodies against SUMO1-DHX35 in long-COVID by Thurner, Lorenz, Fadle, Natalie, Regitz, Evi, Preuss, Klaus-Dieter, Neumann, Frank, Cetin, Onur, Schormann, Claudia, Hoffmann, Marie-Christin, Herr, Christian, Kheiroddin, Parastoo, Rixecker, Torben Millard, Bals, Robert, Muller, Sylviane, Thurner, Bernhard, Kessel, Christoph, Kabesch, Michael, Bewarder, Moritz, Heyne, Kristina, Lensch, Christian, Kos, Igor Age

“…Long COVID is a collection of symptoms as a late sequelae of SARS-CoV-2 infection. It often includes mental symptoms such as cognitive symptoms, persisting…”
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S100A12 Serum Levels and PMN Counts Are Elevated in Childhood Systemic Vasculitides Especially Involving Proteinase 3 Specific Anti-neutrophil Cytoplasmic Antibodies by Brown, Kelly L, Lubieniecka, Joanna M, Armaroli, Giulia, Kessel, Katharina, Gibson, Kristen M, Graham, Jinko, Liu, Dongmeng, Hancock, Robert E W, Ross, Colin J, Benseler, Susanne M, Luqmani, Raashid A, Cabral, David A, Foell, Dirk, Kessel, Christoph

“…Chronic primary systemic vasculitidies (CPV) are a collection of rare diseases involving inflammation in blood vessels, often in multiple organs. CPV can…”
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