Random capillary plasma glucose measurement in the screening of diabetes mellitus in high-risk subjects in Thailand

To assess the usefulness of random capillary plasma glucose (RCPG) measurement in screening for diabetes mellitus in high-risk subjects, a RCPG measurement and a 75-g oral glucose tolerance test (OGTT) were performed in 684 women and 164 men, aged 16–76 years (mean±SD: 41.9±11.3 years). Risk factors...

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Published in:Diabetes research and clinical practice Vol. 51; no. 2; pp. 125 - 131
Main Authors: Puavilai, G., Kheesukapan, P., Chanprasertyotin, S., Chantraraprasert, S., Suwanvilaikorn, S., Nitiyanant, W., Deerochochanawong, C., Benjasuratwong, Y., Munsakul, N., Pongchaiyaikul, C., Kespechara, K., Montreewasuwat, N.
Format: Journal Article
Language:English
Published: Shannon Elsevier Ireland Ltd 01-02-2001
Elsevier Science
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Summary:To assess the usefulness of random capillary plasma glucose (RCPG) measurement in screening for diabetes mellitus in high-risk subjects, a RCPG measurement and a 75-g oral glucose tolerance test (OGTT) were performed in 684 women and 164 men, aged 16–76 years (mean±SD: 41.9±11.3 years). Risk factors included family history of diabetes in first degree relatives (53.8%), obesity (BMI≥27 kg/m 2) in 37.9%, dyslipidemia (78.4%), hypertension, i.e. BP⩾140/90 mmHg (28.5%), and history of gestational diabetes mellitus (16.6%). According to the 1997 ADA/1998 WHO Consultation criteria for a full OGTT, 118 cases (13.9%) were found to have diabetes. Each of 19 cases with RCPG≥13.3 mmol/l had diabetes according to OGTT, 4.7% of 427 cases with RCPG<6.1 mmol/l had diabetes. Among 402 subjects with RCPG between 6.1 and <13.3 mmol/l, 19.7% were found to have diabetes. Thus, 446 (52.6%) of 848 subjects would have been saved from OGTT if RCPG was used as a screening test, in comparison to 33.1% if the cutpoints for RCPG (12.2 and 5.5 mmol/l) recommended by WHO Study Group (1985)/WHO Consultation (1998) were applied. Therefore, RCPG measurement is a useful screening test for the screening of diabetes mellitus in high-risk subjects.
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ISSN:0168-8227
1872-8227
DOI:10.1016/S0168-8227(00)00223-0