Random capillary plasma glucose measurement in the screening of diabetes mellitus in high-risk subjects in Thailand
To assess the usefulness of random capillary plasma glucose (RCPG) measurement in screening for diabetes mellitus in high-risk subjects, a RCPG measurement and a 75-g oral glucose tolerance test (OGTT) were performed in 684 women and 164 men, aged 16–76 years (mean±SD: 41.9±11.3 years). Risk factors...
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Published in: | Diabetes research and clinical practice Vol. 51; no. 2; pp. 125 - 131 |
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Main Authors: | , , , , , , , , , , , |
Format: | Journal Article |
Language: | English |
Published: |
Shannon
Elsevier Ireland Ltd
01-02-2001
Elsevier Science |
Subjects: | |
Online Access: | Get full text |
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Summary: | To assess the usefulness of random capillary plasma glucose (RCPG) measurement in screening for diabetes mellitus in high-risk subjects, a RCPG measurement and a 75-g oral glucose tolerance test (OGTT) were performed in 684 women and 164 men, aged 16–76 years (mean±SD: 41.9±11.3 years). Risk factors included family history of diabetes in first degree relatives (53.8%), obesity (BMI≥27 kg/m
2) in 37.9%, dyslipidemia (78.4%), hypertension, i.e. BP⩾140/90 mmHg (28.5%), and history of gestational diabetes mellitus (16.6%). According to the 1997 ADA/1998 WHO Consultation criteria for a full OGTT, 118 cases (13.9%) were found to have diabetes. Each of 19 cases with RCPG≥13.3 mmol/l had diabetes according to OGTT, 4.7% of 427 cases with RCPG<6.1 mmol/l had diabetes. Among 402 subjects with RCPG between 6.1 and <13.3 mmol/l, 19.7% were found to have diabetes. Thus, 446 (52.6%) of 848 subjects would have been saved from OGTT if RCPG was used as a screening test, in comparison to 33.1% if the cutpoints for RCPG (12.2 and 5.5 mmol/l) recommended by WHO Study Group (1985)/WHO Consultation (1998) were applied. Therefore, RCPG measurement is a useful screening test for the screening of diabetes mellitus in high-risk subjects. |
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Bibliography: | ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23 |
ISSN: | 0168-8227 1872-8227 |
DOI: | 10.1016/S0168-8227(00)00223-0 |