Search Results - "Keshavan, Sandeep"
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Understanding The Benefits and Risks of Sustainable Nanomaterials in a Research Environment
Published in Chimia (26-06-2024)“…Nanomaterials hold immense potential for numerous applications in energy, health care, and environmental sectors, playing an important role in our daily lives…”
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A Biodegradable Multifunctional Graphene Oxide Platform for Targeted Cancer Therapy
Published in Advanced functional materials (01-09-2019)“…The design of multifunctional materials able to both selectively deliver a drug into cells in a targeted manner and display an enhanced propensity for…”
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Development of multi-drug loaded PEGylated nanodiamonds to inhibit tumor growth and metastasis in genetically engineered mouse models of pancreatic cancer
Published in Nanoscale (21-11-2019)“…Pancreatic ductal adenocarcinoma (PDAC) is a devastating disease. Nanomedicine, however, offers new opportunities to facilitate drug delivery in PDAC. Our…”
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Differential Effect of SARS-CoV-2 Spike Glycoprotein 1 on Human Bronchial and Alveolar Lung Mucosa Models: Implications for Pathogenicity
Published in Viruses (17-12-2021)“…The SARS-CoV-2 spike protein mediates attachment of the virus to the host cell receptor and fusion between the virus and the cell membrane. The S1 subunit of…”
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Understanding Macrophage Interaction with Antimony-Doped Tin Oxide Plasmonic Nanoparticles
Published in Cells (Basel, Switzerland) (01-09-2024)“…Antimony-doped tin oxide nanoparticles (ATO NPs) have emerged as a promising tool in biomedical applications, namely robust photothermal effects upon…”
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High-Dose Exposure to Polymer-Coated Iron Oxide Nanoparticles Elicits Autophagy-Dependent Ferroptosis in Susceptible Cancer Cells
Published in Nanomaterials (Basel, Switzerland) (24-05-2023)“…Ferroptosis, a form of iron-dependent, lipid peroxidation-driven cell death, has been extensively investigated in recent years, and several studies have…”
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Quantitative Super-Resolution Microscopy to Assess Adhesion of Neuronal Cells on Single-Layer Graphene Substrates
Published in Membranes (Basel) (15-11-2021)“…Single Layer Graphene (SLG) has emerged as a critically important nanomaterial due to its unique optical and electrical properties and has become a potential…”
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Profiling of Sub-Lethal in Vitro Effects of Multi-Walled Carbon Nanotubes Reveals Changes in Chemokines and Chemokine Receptors
Published in Nanomaterials (Basel, Switzerland) (30-03-2021)“…Engineered nanomaterials are potentially very useful for a variety of applications, but studies are needed to ascertain whether these materials pose a risk to…”
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Current Challenges to Align Inflammatory Key Events in Animals and Lung Cell Models In Vitro
Published in Chemical research in toxicology (21-10-2024)“…With numerous novel and innovative in vitro models emerging every year to reduce or replace animal testing, there is an urgent need to align the design,…”
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Comparing species-different responses in pulmonary fibrosis research: Current understanding of in vitro lung cell models and nanomaterials
Published in European journal of pharmaceutical sciences (01-04-2023)“…Pulmonary fibrosis (PF) is a chronic, irreversible lung disease that is typically fatal and characterized by an abnormal fibrotic response. As a result, vast…”
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Rethinking of TEER measurement reporting for epithelial cells grown on permeable inserts
Published in European journal of pharmaceutical sciences (01-09-2023)“…Transepithelial electrical resistance (TEER) measures electrical resistance across epithelial tissue barriers involving confluent layer(s) of cells. TEER…”
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Developmental refinement of synaptic transmission on micropatterned single layer graphene
Published in Acta biomaterialia (01-01-2018)“…[Display omitted] Interfacing neurons with graphene, a single atomic layer of sp2 hybridized C-atoms, is a key paradigm in understanding how to exploit the…”
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Multi-walled carbon nanotubes trigger lysosome-dependent cell death (pyroptosis) in macrophages but not in neutrophils
Published in Nanotoxicology (01-11-2021)“…Carbon nanotubes (CNTs) have been extensively investigated, and several studies have shown that multi-walled CNTs can trigger inflammation and fibrosis in…”
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Two‐Dimensional Transition Metal Dichalcogenides Trigger Trained Immunity in Human Macrophages through Epigenetic and Metabolic Pathways
Published in Small (Weinheim an der Bergstrasse, Germany) (01-05-2022)“…Trained immunity is a recently described phenomenon whereby cells of the innate immune system undergo long‐term epigenetic and/or metabolic reprogramming…”
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Nano-bio interactions: a neutrophil-centric view
Published in Cell death & disease (29-07-2019)“…Neutrophils are key components of the innate arm of the immune system and represent the frontline of host defense against intruding pathogens. However,…”
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Induced inhomogeneity in graphene work function due to graphene - TiO2/Ag/glass substrate interaction
Published in Thin solid films (30-04-2017)“…Important issues in optoelectronic devices based on exfoliated graphene are the electronic noise due to the interaction between graphene flakes and the…”
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Induced inhomogeneity in graphene work function due to graphene - TiO 2 /Ag/glass substrate interaction
Published in Thin solid films (01-04-2017)Get full text
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Single layer graphene functionalized MEA for enhanced detection of neuronal network development
Published in Sensors and actuators. B, Chemical (20-12-2018)“…•Commercial multi-electrode-arrays (MEAs) well functionalized with single layer graphene (SLG) transferred via wet etching.•Spontaneous activity of neuronal…”
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Electrophysiology of Patterned Neuronal Networks on Monolayer Graphene
Published in Biophysical journal (16-02-2016)Get full text
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