Search Results - "Kesavan, DineshKumar"

Identification of natural compound inhibitors for multidrug efflux pumps of Escherichia coli and Pseudomonas aeruginosa using in silico high-throughput virtual screening and in vitro validation by Aparna, Vasudevan, Dineshkumar, Kesavan, Mohanalakshmi, Narasumani, Velmurugan, Devadasan, Hopper, Waheeta

“…Pseudomonas aeruginosa and Escherichia coli are resistant to wide range of antibiotics rendering the treatment of infections very difficult. A main mechanism…”
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Integrative analysis of outer membrane vesicles proteomics and whole-cell transcriptome analysis of eravacycline induced Acinetobacter baumannii strains by Kesavan, DineshKumar, Vasudevan, Aparna, Wu, Liang, Chen, Jianguo, Su, Zhaoliang, Wang, Shengjun, Xu, Huaxi

“…Acinetobacter baumannii is a multidrug-resistant (MDR) hazardous bacterium with very high antimicrobial resistance profiles. Outer membrane vesicles (OMVs)…”
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Bacterial bug-out bags: outer membrane vesicles and their proteins and functions by Dineshkumar, Kesavan, Aparna, Vasudevan, Wu, Liang, Wan, Jie, Abdelaziz, Mohamod Hamed, Su, Zhaoliang, Wang, Shengjun, Xu, Huaxi

“…Among the major bacterial secretions, outer membrane vesicles (OMVs) are significant and highly functional. The proteins and other biomolecules identified…”
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The innate resistome of “recalcitrant” Acinetobacter baumannii and the role of nanoparticles in combating these MDR pathogens by Aparna, Vasudevan, Dineshkumar, Kesavan, Su, Zhaoliang, Wang, Shengjun, Xu, Huaxi

“…Acinetobacter baumannii , a nosocomial pathogen, and member of ESKAPE bacteria are currently a global threat. A. baumannii is equipped naturally laden with…”
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Ligand Based-Pharmacophore Modeling and Extended Bi oactivity Prediction for Salinosporamide A, B and C from Marine Actino mycetes Salinispora tropica by Dineshkumar, Kesavan, Vasudevan, Aparna, Hopper, Waheeta

“…Actinomycetes produce structurally unique secondary metabolites with pharmaceutically essential bioactivities. Salinispora, an obligate marine actinomycete,…”
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Pterostilbene-mediated Nrf2 activation: Mechanistic insights on Keap1:Nrf2 interface by Bhakkiyalakshmi, Elango, Dineshkumar, Kesavan, Karthik, Suresh, Sireesh, Dornadula, Hopper, Waheeta, Paulmurugan, Ramasamy, Ramkumar, Kunka Mohanram

“…[Display omitted] The discovery of Keap1–Nrf2 protein–protein interaction (PPI) inhibitors has become a promising strategy to develop novel lead molecules…”
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ILC2-derived IL-9 inhibits colorectal cancer progression by activating CD8+ T cells by Wan, Jie, Wu, Yinqiu, Huang, Lan, Tian, Yu, Ji, Xiaoyun, Abdelaziz, Mohamed Hamed, Cai, Wei, Dineshkumar, Kesavan, Lei, Yuqing, Yao, Shun, Sun, Caixia, Su, Zhaoliang, Wang, Shengjun, Xu, Huaxi

“…Group 2 innate lymphoid cells (ILC2s), characterized by secretion of type 2 cytokines, regulate multiple immune responses. ILC2s are found in different tumor…”
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HMGB1-induced ILC2s activate dendritic cells by producing IL-9 in asthmatic mouse model by Wan, Jie, Huang, Lan, Ji, Xiaoyun, Yao, Shun, Hamed Abdelaziz, Mohamed, Cai, Wei, Wang, Huixuan, Cheng, Jianjun, Dineshkumar, Kesavan, Aparna, Vasudevan, Su, Zhaoliang, Wang, Shengjun, Xu, Huaxi

“…•HMGB1 is increased in asthma mice.•HMGB1 can promote ILC2 to secrete IL-9.•Up-regulated ILC2s-derived IL-9 can activate dendritic cells in asthma. Asthma is a…”
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Biological Activity of Sporolides A and B from Salinispora tropica: in silico Target Prediction Using Ligand-Based Pharmacophore Mapping and in vitro activity Validation on HIV-1 Reverse Transcriptase by Dineshkumar, Kesavan, Aparna, Vasudevan, Madhuri, Kantilal Z., Hopper, Waheeta

“…Sporolides A and B are novel polycyclic macrolides from the obligate marine actinomycetes, Salinispora tropica. The unique and novel structure of sporolides…”
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