Search Results - "Kesavan, Dinesh Kumar"
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Alternatively activated macrophages; a double-edged sword in allergic asthma
Published in Journal of translational medicine (05-02-2020)“…Macrophages are heterogenous phagocytic cells with an important role in the innate immunity. They are, also, significant contributors in the adaptive immune…”
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Bacterial outer membrane vesicles, a potential vaccine candidate in interactions with host cells based
Published in Diagnostic pathology (11-12-2018)“…Both Gram-Positive and Gram-Negative bacteria can secrete outer membrane vesicles (OMVs) in their growth and metabolism process. Originally, OMVs were…”
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Efflux pumps potential drug targets to circumvent drug Resistance – Multi drug efflux pumps of Helicobacter pylori
Published in Materials today : proceedings (2021)“…Helicobacter pylori (H. pylori) being grouped as Group1 Carcinogen by World Health Organisation (WHO) is arising as multidrug resistant (MDR), necessitating…”
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Vesicle-Mediated Dendritic Cell Activation in Acinetobacter baumannii Clinical Isolate, which Contributes to Th2 Response
Published in Journal of immunology research (2019)“…Acinetobacter baumannii, as a nonfermentation Gram-negative bacterium, mainly cause nosocomial infections in critically ill patients. With the widespread of…”
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Genome and Transcriptome Analysis of A. baumannii's “Transient” Increase in Drug Resistance under Tigecycline Pressure
Published in Journal of global antimicrobial resistance. (01-09-2020)“…•Completed the process of drug resistance enhancement and recovery of Acinetobacter baumannii in vitro, further understanding the phenomenon of drug…”
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Proteomic Network of Antibiotic-Induced Outer Membrane Vesicles Released by Extensively Drug-Resistant Elizabethkingia anophelis
Published in Microbiology spectrum (31-08-2022)“…Elizabethkingia anophelis, a nonfermenting Gram-negative bacterium, causes life-threatening health care-associated infections. E. anophelis harbors multidrug…”
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Elizabethkingia anophelis outer membrane vesicles as a novel vaccine candidate against infection: insights into immune response and potential for passive immunity
Published in mSphere (20-12-2023)“…, a Gram-negative pathogen, causes infections such as bacteraemia, pneumonia, and neonatal meningitis. The pathogen resists most antimicrobial classes, making…”
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In Silico and In Vitro Screening of Natural Compounds as Broad-Spectrum β-Lactamase Inhibitors against Acinetobacter baumannii New Delhi Metallo-β-lactamase-1 (NDM-1)
Published in BioMed research international (10-03-2022)“…Antibiotic resistance is one of the significant problems globally; there is an increase in resistance with introducing every new class of antibiotics. Further,…”
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Atomic level and structural understanding of natural ligands inhibiting Helicobacter pylori peptide deformylase through ligand and receptor based screening, SIFT, molecular dynamics and DFT - a structural computational approach
Published in Journal of biomolecular structure & dynamics (24-05-2023)“…Helicobacter pylori is a Gram-negative microaerophilic gastric pathogen, responsible for the cause of peptic ulcer around half of the global population…”
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Downregulated Rac1 promotes apoptosis and inhibits the clearance of apoptotic cells in airway epithelial cells, which may be associated with airway hyper‐responsiveness in asthma
Published in Scandinavian journal of immunology (01-05-2019)“…The accumulation of airway apoptotic cells may be an important factor causing airway hyper‐responsiveness (AHR). Whether the apoptotic cells can be promptly…”
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