Search Results - "Kersten, Brigit E"
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Photoacoustic and high-frequency ultrasound imaging of systemic sclerosis patients
Published in Arthritis research & therapy (12-01-2021)“…Systemic sclerosis starts with an early phase characterized by Raynaud's phenomenon, puffy fingers/hands, autoantibodies, and a scleroderma nailfold…”
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Autoantibody profiles in systemic sclerosis; a comparison of diagnostic tests
Published in Autoimmunity (Chur, Switzerland) (03-04-2021)“…Autoimmune antibody profiling plays a prominent role in both classification and prognosis of systemic sclerosis (SSc). In the last years novel autoantibodies…”
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Hit hard and early: analysing the effects of high-dose methylprednisolone on nailfold capillary changes and biomarkers in very early systemic sclerosis: study protocol for a 12-week randomised controlled trial
Published in Current controlled trials in cardiovascular medicine (22-08-2018)“…Mounting evidence indicates that inflammatory mechanisms drive systemic sclerosis (SSc) vasculopathy and fibrosis, especially early in the disease. Therefore,…”
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Diagnostic profiles for precision medicine in systemic sclerosis; stepping forward from single biomarkers towards pathophysiological panels
Published in Autoimmunity reviews (01-05-2020)“…Systemic sclerosis (SSc) is an autoimmune disease which is characterized by vasculopathy, tissue fibrosis and activation of the innate and adaptive immune…”
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Efficacy of methylprednisolone in very early systemic sclerosis: results of the "Hit hard and early'' randomized controlled trial
Published in Rheumatology (Oxford, England) (29-03-2024)“…We hypothesized that glucocorticoids would induce remission in very early Systemic Sclerosis patients by inhibition of inflammation driving the disease. We…”
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Treatment with cyclophosphamide i.v. pulse therapy is an option for effective treatment of skin fibrosis in patients with early systemic sclerosis
Published in Rheumatology (Oxford, England) (01-07-2020)“…Abstract Objectives SSc is a autoimmune disease characterized by fibrosis of the skin and internal organs. There is a lack of evidence for the efficacy of i.v…”
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