Search Results - "Kershaw, Rachael M"

Use of a molecular beacon to track the activity of base excision repair protein OGG1 in live cells by Mirbahai, Leda, Kershaw, Rachael M., Green, Richard M., Hayden, Rachel E., Meldrum, Rosalind A., Hodges, Nikolas J.

“…An abundant form of DNA damage caused by reactive oxygen species is 8-oxo-7,8-dihydroguanine for which the base excision repair protein 8-oxoguanine-DNA…”
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Repair of oxidative DNA damage is delayed in the Ser326Cys polymorphic variant of the base excision repair protein OGG1 by KERSHAW, Rachael M, HODGES, Nikolas J

“…Gene-environment interactions influence an individual's risk of disease development. A common human 8-oxoguanine DNA glycosylase 1 (OGG1) variant,…”
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Generation of cell lines to investigate redox modulated dimer formation of Cys326-hOGG1 by Kershaw, Rachael M, Smart, Daniel J, Hodges, Nikolas J

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Development of a novel technique to quantify activity and localisation of the base excision repair protein OGG1 in individual cells and its induction by the pro-oxidant potassium bromate by Mirbahai, Leda, Kershaw, Rachael M, Meldrum, Rosalind A, Hodges, Nikolas J

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Abstract 4164: uPA modulates angiogenesis through transcriptional regulation of vascular endothelial growth factor (VEGF) receptors VEGFR1 and VEGFR2 by Stepanova, Victoria, Jayaraman, Padma Sheela, Zaitsev, Sergei V., Lebedeva, Tatiana, Kershaw, Rachael M., Cines, Douglas B.

“…The urokinase-type plasminogen activator (uPA) system has multifunctional roles in neoplastic grows and metastasis, affecting cancer cell proliferation,…”
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