Search Results - "Kersh, Ellen"

Advances in Sexually Transmitted Infection Testing at Home and in Nonclinical Settings Close to the Home by Kersh, Ellen N.

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At-Home Specimen Self-Collection and Self-Testing for Sexually Transmitted Infection Screening Demand Accelerated by the COVID-19 Pandemic: a Review of Laboratory Implementation Issues by Kersh, Ellen N, Shukla, Mayur, Raphael, Brian H, Habel, Melissa, Park, Ina

“…The coronavirus disease 2019 (COVID-19) pandemic reduced the sexually transmitted infection (STI) testing volume due to social-distancing and stay-at-home…”
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At-Home Diagnostics Solutions for Chlamydia and Gonorrhea by Kersh, Ellen N, Mena, Leandro A

“…This Viewpoint discusses the US Food and Drug Administration’s authorization of marketing an at-home testing system for chlamydia and gonorrhea as a good first…”
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Accelerate US development of syphilis self-tests by Kersh, Ellen N., Cao, Weiping, Owen, S. Michele

“…Letter to the Editor…”
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Characterization of a Neisseria gonorrhoeae Ciprofloxacin panel for an antimicrobial resistant Isolate Bank by Liu, Hsi, Tang, Kevin, Pham, Cau D, Schmerer, Matthew, Kersh, Ellen N, Raphael, Brian H

“…Neisseria gonorrhoeae (gonococcus) infection is one of the most commonly reported nationally notifiable conditions in the United States. Gonococcus has…”
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A Commentary on Current Diagnostic Challenges and Research Needs for Evaluating Reproductive Sequelae of Sexually Transmitted Infections by Kersh, Ellen N, Geisler, William M

“…Abstract Advancing the understanding of pelvic inflammatory disease (PID) requires access to advanced diagnostic approaches for evaluating reproductive…”
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Considerations for Endpoint Titer Determination in Syphilis Testing Using Newly Marketed, Automated Rapid Plasma Reagin Instruments by Shukla, Mayur, Pereira, Lara, Sun, Yongcheng, Fakile, Yetunde F., Kersh, Ellen N., Cao, Weiping

“…Syphilis is a sexually transmitted disease (STD) caused by the bacterium Treponema palladium. The resurgence of syphilis in the last 2 decades is a major…”
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Evidence Review for Centers for Disease Control and Prevention Guidance Development on Laboratory Testing to Detect Treponema pallidum Infection (Syphilis) by Kersh, Ellen N, Workowski, Kimberly A

“…Abstract The articles in this supplement address key questions on syphilis diagnostics, provide reference tables of test performances, and discuss optimal…”
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World Health Organization Enhanced Gonococcal Antimicrobial Surveillance Programme, Cambodia, 2023 by Ouk, Vichea, Say, Heng Lon, Virak, Mot, Deng, Serakea, Frankson, Rebekah, McDonald, Robert, Kersh, Ellen N, Wi, Teodora, Maatouk, Ismael, van Hal, Sebastiaan, Lahra, Monica M

“…To determine antimicrobial susceptibility of Neisseria gonorrhoeae, we analyzed phenotypes and genomes of 72 isolates collected in Cambodia in 2023. Of those,…”
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Update to CDC's Treatment Guidelines for Gonococcal Infection, 2020 by St Cyr, Sancta, Barbee, Lindley, Workowski, Kimberly A, Bachmann, Laura H, Pham, Cau, Schlanger, Karen, Torrone, Elizabeth, Weinstock, Hillard, Kersh, Ellen N, Thorpe, Phoebe

“…Sexually transmitted infections (STIs) caused by the bacteria Neisseria gonorrhoeae (gonococcal infections) have increased 63% since 2014 and are a cause of…”
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Advantages and limitations of current diagnostic laboratory approaches in syphilis and congenital syphilis by Cao, Weiping, Thorpe, Phoebe G, O'Callaghan, Kevin, Kersh, Ellen N

“…The reemergence of syphilis, especially congenital syphilis, presents a significant public health threat. Accurate diagnosis of syphilis depends on recognition…”
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Gonococcal Clinical Strains Bearing a Common gdhR Single Nucleotide Polymorphism That Results in Enhanced Expression of the Virulence Gene lctP Frequently Possess a mtrR Promoter Mutation That Decreases Antibiotic Susceptibility by Ayala, Julio C, Schmerer, Matthew W, Kersh, Ellen N, Unemo, Magnus, Shafer, William M

“…GdhR is a transcriptional repressor of the virulence factor gene , which encodes a unique l-lactate permease that has been linked to pathogenesis of Neisseria…”
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Targeting α4β7 integrin reduces mucosal transmission of simian immunodeficiency virus and protects gut-associated lymphoid tissue from infection by Byrareddy, Siddappa N, Kallam, Brianne, Arthos, James, Cicala, Claudia, Nawaz, Fatima, Hiatt, Joseph, Kersh, Ellen N, McNicholl, Janet M, Hanson, Debra, Reimann, Keith A, Brameier, Markus, Walter, Lutz, Rogers, Kenneth, Mayne, Ann E, Dunbar, Paul, Villinger, Tara, Little, Dawn, Parslow, Tristram G, Santangelo, Philip J, Villinger, Francois, Fauci, Anthony S, Ansari, Aftab A

“…Aftab Ansari and his colleagues show that antibody-mediated masking of α4β7 integrin impedes intravaginal transmission of simian immunodeficiency virus in…”
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Rationale for a Neisseria gonorrhoeae Susceptible–only Interpretive Breakpoint for Azithromycin by Kersh, Ellen N, Allen, Vanessa, Ransom, Eric, Schmerer, Matthew, Cyr, Sancta, Workowski, Kim, Weinstock, Hillard, Patel, Jean, Ferraro, Mary Jane

“…Abstract Background Azithromycin (AZI) is recommended with ceftriaxone (CRO) for treatment of uncomplicated gonococcal urethritis and cervicitis in the United…”
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Mechanistic Basis for Decreased Antimicrobial Susceptibility in a Clinical Isolate of Neisseria gonorrhoeae Possessing a Mosaic-Like mtr Efflux Pump Locus by Rouquette-Loughlin, Corinne E, Reimche, Jennifer L, Balthazar, Jacqueline T, Dhulipala, Vijaya, Gernert, Kim M, Kersh, Ellen N, Pham, Cau D, Pettus, Kevin, Abrams, A Jeanine, Trees, David L, St Cyr, Sancta, Shafer, William M

“…Recent reports suggest that mosaic-like sequences within the ( ultiple ransferable esistance) efflux pump locus of , likely originating from commensal sp. by…”
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Genetic Similarity of Gonococcal Homologs to Meningococcal Outer Membrane Proteins of Serogroup B Vaccine by Marjuki, Henju, Topaz, Nadav, Joseph, Sandeep J, Gernert, Kim M, Kersh, Ellen N, Wang, Xin

“…The human pathogens and share high genome identity. Retrospective analysis of surveillance data from New Zealand indicates the potential cross-protective…”
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Novel strain of multidrug non-susceptible Neisseria gonorrhoeae in the USA by Reimche, Jennifer L, Pham, Cau D, Joseph, Sandeep J, Hutton, Shelby, Cartee, John C, Ruan, Yuheng, Breaux, Mandy, Ivanof, Caryn, Joshi, Akita, DeMartino, Mary, Kirby, James E, Barbee, Lindley A, Kersh, Ellen N, Roosevelt, Kathleen A, Hsu, Katherine K

“…The Massachusetts Department of Public Health and CDC then collaborated with the originating community health centre and microbiology laboratory to increase…”
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Evidence of Recent Genomic Evolution in Gonococcal Strains With Decreased Susceptibility to Cephalosporins or Azithromycin in the United States, 2014-2016 by Thomas, Jesse C, Seby, Sandra, Abrams, A Jeanine, Cartee, Jack, Lucking, Sean, Vidyaprakash, Eshaw, Schmerer, Matthew, Pham, Cau D, Hong, Jaeyoung, Torrone, Elizabeth, Cyr, Sancta St, Shafer, William M, Bernstein, Kyle, Kersh, Ellen N, Gernert, Kim M

“…Given the lack of new antimicrobials or a vaccine, understanding the evolutionary dynamics of Neisseria gonorrhoeae is a significant public and global health…”
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Phylogenomic analysis reveals persistence of gonococcal strains with reduced-susceptibility to extended-spectrum cephalosporins and mosaic penA-34 by Thomas, Jesse C., Joseph, Sandeep J., Cartee, John C., Pham, Cau D., Schmerer, Matthew W., Schlanger, Karen, St. Cyr, Sancta B., Kersh, Ellen N., Raphael, Brian H.

“…The recent emergence of strains of Neisseria gonorrhoeae associated with treatment failures to ceftriaxone, the foundation of current treatment options, has…”
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Emergence and evolution of mosaic penA-60 and penA-237 alleles in a Neisseria gonorrhoeae core genogroup that was historically susceptible to extended spectrum cephalosporins by Thomas Iv, Jesse C, Cartee, John C, Hebrank, Katherine, St Cyr, Sancta B, Schlanger, Karen, Raphael, Brian H, Kersh, Ellen N, Joseph, Sandeep J

“…(Ng) has successively developed resistance to all previously recommended antimicrobial therapies, with ceftriaxone being the last option for monotherapy of…”
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