Search Results - "Kerschbaumer, J"
-
1
Human anti-macrophage migration inhibitory factor antibodies inhibit growth of human prostate cancer cells in vitro and in vivo
Published in Molecular cancer therapeutics (01-07-2013)“…Macrophage migration inhibitory factor (MIF) is a proinflammatory cytokine, originally discovered for its eponymous effect and now known for pleiotropic…”
Get full text
Journal Article -
2
-
3
Now you see me - the use of sodium fluoresceine for resection of brain metastases
Published in Brain & spine (2022)Get full text
Journal Article -
4
-
5
Impact of GAP-43 and actin expression on the outcome and overall survival in diffuse and anaplastic gliomas
Published in Brain & spine (2022)Get full text
Journal Article -
6
Serious tumor seeding after brainstem biopsy and its treatment—a case report and review of the literature
Published in Acta neurochirurgica (01-04-2017)“…Stereotactic brain biopsies for histopathological diagnosis are a common technique in case of intracranial lesions, particularly in those not amenable for…”
Get full text
Journal Article -
7
SP 10. Innsbruck experience in neuropathic pain syndromes: Re-think and re-construct old methods for better results
Published in Clinical neurophysiology (01-09-2016)“…Introduction In the last 25 years neuromodulation by deep brain stimulation gained widely acceptance starting in the field of movement disorders and getting…”
Get full text
Journal Article -
8
Evaluating the Performance of Small Wastewater Treatment Plants
Published in Frontiers in environmental science (15-07-2022)“…An evaluation of the treatment performance of small wastewater treatment plants with the capacity of ≤50 PE (population equivalent) was carried out using data…”
Get full text
Journal Article -
9
Cadaveric study of ergonomics and performance using a robotic exoscope with a head-mounted display in spine surgery
Published in Brain & spine (2022)Get full text
Journal Article -
10
Preoperative prediction of language function by diffusion tensor imaging
Published in Brain informatics (01-09-2017)“…For surgery of eloquent tumors in language areas, the accepted gold standard is functional mapping through direct cortical stimulation (DCS) in awake patients…”
Get full text
Journal Article -
11
Optimization of an Antibody Light Chain Framework Enhances Expression, Biophysical Properties and Pharmacokinetics
Published in Antibodies (Basel) (06-09-2019)“…Efficacy, safety, and manufacturability of therapeutic antibodies are influenced by their biopharmaceutical and biophysical properties. These properties can be…”
Get full text
Journal Article -
12
Preclinical Evaluation of ON203, A Novel Bioengineered mAb Targeting Oxidized Macrophage Migration Inhibitory Factor as an Anticancer Therapeutic
Published in Molecular cancer therapeutics (04-05-2023)“…High levels of macrophage migration inhibitory factor (MIF) in patients with cancer are associated with poor prognosis. Its redox-dependent conformational…”
Get full text
Journal Article -
13
Targeting of oxidized Macrophage Migration Inhibitory Factor (oxMIF) with antibody ON104 attenuates the severity of glomerulonephritis
Published in PloS one (07-10-2024)“…The oxidized form of Macrophage Migration Inhibitory Factor (oxMIF) has been identified as the disease-related isoform of MIF, exerting pathological functions…”
Get full text
Journal Article -
14
Role of the Cysteine 81 Residue of Macrophage Migration Inhibitory Factor as a Molecular Redox Switch
Published in Biochemistry (Easton) (06-03-2018)“…Macrophage migration inhibitory factor (MIF) is a pro-inflammatory and tumor-promoting cytokine that occurs in two redox-dependent immunologically distinct…”
Get full text
Journal Article -
15
Oxidized macrophage migration inhibitory factor is a potential new tissue marker and drug target in cancer
Published in Oncotarget (08-11-2016)“…Macrophage migration inhibitory factor (MIF) is a pleiotropic cytokine, which was shown to be upregulated in cancers and to exhibit tumor promoting properties…”
Get full text
Journal Article -
16
Higher expression of Fab antibody fragments in a CHU cell line at reduced temperature
Published in Biotechnology and bioengineering (20-11-2003)Get full text
Journal Article -
17
P09.44 One year with Optune in Austria: First report on clinical experiences
Published in Neuro-oncology (Charlottesville, Va.) (01-05-2017)“…Objective: Tumor Treating Fields (TTFields) consist of intermediate frequency alternating electric fields that are delivered through 4 transducer arrays,…”
Get full text
Journal Article -
18
An Antibody Specific for Coagulation Factor IX Enhances the Activity of the Intrinsic Factor X-activating Complex
Published in The Journal of biological chemistry (24-09-2004)“…During hemostasis the zymogen factor X (FX) is converted into its enzymatically active form factor Xa by the intrinsic FX-activating complex. This complex…”
Get full text
Journal Article -
19
Selective Targeting of a Disease-Related Conformational Isoform of Macrophage Migration Inhibitory Factor Ameliorates Inflammatory Conditions
Published in The Journal of immunology (1950) (01-09-2015)“…Macrophage migration inhibitory factor (MIF), a proinflammatory cytokine and counterregulator of glucocorticoids, is a potential therapeutic target. MIF is…”
Get full text
Journal Article -
20
Single-Chain Fv Fusion Proteins Suitable as Coating and Detecting Reagents in a Double Antibody Sandwich Enzyme-Linked Immunosorbent Assay
Published in Analytical biochemistry (01-07-1997)“…A recombinant enzyme-linked immunosorbent assay (ELISA) system, entirely based on antibody fragments, is described here as an attractive alternative to assays…”
Get full text
Journal Article