Search Results - "Kerr–Conte, Julie"

Insulin-producing organoids engineered from islet and amniotic epithelial cells to treat diabetes by Lebreton, Fanny, Lavallard, Vanessa, Bellofatto, Kevin, Bonnet, Romain, Wassmer, Charles H., Perez, Lisa, Kalandadze, Vakhtang, Follenzi, Antonia, Boulvain, Michel, Kerr-Conte, Julie, Goodman, David J., Bosco, Domenico, Berney, Thierry, Berishvili, Ekaterine

“…Maintaining long-term euglycemia after intraportal islet transplantation is hampered by the considerable islet loss in the peri-transplant period attributed to…”
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Shielding islets with human amniotic epithelial cells enhances islet engraftment and revascularization in a murine diabetes model by Lebreton, Fanny, Bellofatto, Kevin, Wassmer, Charles H., Perez, Lisa, Lavallard, Vanessa, Parnaud, Géraldine, Cottet‐Dumoulin, David, Kerr‐Conte, Julie, Pattou, François, Bosco, Domenico, Othenin‐Girard, Véronique, Martinez de Tejada, Begoña, Berishvili, Ekaterine

“…Hypoxia is a major cause of considerable islet loss during the early posttransplant period. Here, we investigate whether shielding islets with human amniotic…”
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MST1 is a key regulator of beta cell apoptosis and dysfunction in diabetes by Ardestani, Amin, Paroni, Federico, Azizi, Zahra, Kaur, Supreet, Khobragade, Vrushali, Yuan, Ting, Frogne, Thomas, Tao, Wufan, Oberholzer, Jose, Pattou, Francois, Kerr Conte, Julie, Maedler, Kathrin

“…Type 1 diabetes (T1D) and type 2 diabetes (T2D) are both hallmarked by loss of insulin-producing pancreatic beta cells. Kathrin Maedler and her colleagues now…”
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Transient receptor potential melastatin-related 7 channel is overexpressed in human pancreatic ductal adenocarcinomas and regulates human pancreatic cancer cell migration by Rybarczyk, Pierre, Gautier, Mathieu, Hague, Frédéric, Dhennin-Duthille, Isabelle, Chatelain, Denis, Kerr-Conte, Julie, Pattou, François, Regimbeau, Jean-Marc, Sevestre, Henri, Ouadid-Ahidouch, Halima

“…Pancreatic ductal adenocarcinoma (PDAC) is one of the most aggressive forms of cancer with a tendency to invade surrounding healthy tissues, leading to a…”
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Pharmacological approach to understanding the control of insulin secretion in human islets by Henquin, Jean‐Claude, Dufrane, Denis, Gmyr, Valery, Kerr‐Conte, Julie, Nenquin, Myriam

“…Aims To understand better the control of insulin secretion by human β cells and to identify similarities to and differences from rodent models. Methods Dynamic…”
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A human antibody against pathologic IAPP aggregates protects beta cells in type 2 diabetes models by Wirth, Fabian, Heitz, Fabrice D., Seeger, Christine, Combaluzier, Ioana, Breu, Karin, Denroche, Heather C., Thevenet, Julien, Osto, Melania, Arosio, Paolo, Kerr-Conte, Julie, Verchere, C. Bruce, Pattou, François, Lutz, Thomas A., Donath, Marc Y., Hock, Christoph, Nitsch, Roger M., Grimm, Jan

“…In patients with type 2 diabetes, pancreatic beta cells progressively degenerate and gradually lose their ability to produce insulin and regulate blood…”
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Neuromedin U uses Gαi2 and Gαo to suppress glucose-stimulated Ca2+ signaling and insulin secretion in pancreatic β cells by Zhang, Weidong, Sakoda, Hideyuki, Nakazato, Yuki, Islam, Md Nurul, Pattou, François, Kerr-Conte, Julie, Nakazato, Masamitsu

“…Neuromedin U (NMU), a highly conserved peptide in mammals, is involved in a wide variety of physiological processes, including impairment of pancreatic β-cell…”
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Heterogeneity of Human Pancreatic Islet Isolation Around Europe: Results of a Survey Study by Nano, Rita, Kerr-Conte, Julie A., Scholz, Hanne, Engelse, Marten, Karlsson, Marie, Saudek, Frantisek, Bosco, Domenico, Antonioli, Barbara, Bertuzzi, Federico, Johnson, Paul R.V., Ludwing, Barbara, Ling, Zhidong, De Paep, Diedert L., Keymeulen, Bart, Pattou, François, Berney, Thierry, Korsgren, Olle, de Koning, Eelco, Piemonti, Lorenzo

“…BACKGROUND.Europe is currently the most active region in the field of pancreatic islet transplantation, and many of the leading groups are actually achieving…”
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Islets for Research: Nothing Is Perfect, but We Can Do Better by Nano, Rita, Kerr-Conte, Julie A, Bosco, Domenico, Karlsson, Marie, Lavallard, Vanessa, Melzi, Raffaella, Gmyr, Valery, Mercalli, Alessia, Berney, Thierry, Pattou, François, Korsgren, Olle, Piemonti, Lorenzo

“…In December 2018, and began requiring authors of papers reporting data obtained from studies on human islets to report critical characteristics of the human…”
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The challenge of HLA donor specific antibodies in the management of pancreatic islet transplantation: an illustrative case-series by Maanaoui, Mehdi, Chetboun, Mikael, Top, Isabelle, Elsermans, Vincent, Kerr-Conte, Julie, Le Mapihan, Kristell, Defrance, Frederique, Gmyr, Valéry, Hubert, Thomas, Labalette, Myriam, Hazzan, Marc, Vantyghem, Marie-Christine, Pattou, François

“…Islet transplantation is a unique paradigm in organ transplantation, since multiple donors are required to achieve complete insulin-independence. Preformed or…”
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LDHB contributes to the regulation of lactate levels and basal insulin secretion in human pancreatic β cells by Cuozzo, Federica, Viloria, Katrina, Shilleh, Ali H., Nasteska, Daniela, Frazer-Morris, Charlotte, Tong, Jason, Jiao, Zicong, Boufersaoui, Adam, Marzullo, Bryan, Rosoff, Daniel B., Smith, Hannah R., Bonner, Caroline, Kerr-Conte, Julie, Pattou, Francois, Nano, Rita, Piemonti, Lorenzo, Johnson, Paul R.V., Spiers, Rebecca, Roberts, Jennie, Lavery, Gareth G., Clark, Anne, Ceresa, Carlo D.L., Ray, David W., Hodson, Leanne, Davies, Amy P., Rutter, Guy A., Oshima, Masaya, Scharfmann, Raphaël, Merrins, Matthew J., Akerman, Ildem, Tennant, Daniel A., Ludwig, Christian, Hodson, David J.

“…Using 13C6 glucose labeling coupled to gas chromatography-mass spectrometry and 2D 1H-13C heteronuclear single quantum coherence NMR spectroscopy, we have…”
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Primary Graft Function and 5 Year Insulin Independence After Pancreas and Islet Transplantation for Type 1 Diabetes: A Retrospective Parallel Cohort Study by Chetboun, Mikael, Masset, Christophe, Maanaoui, Mehdi, Defrance, Frédérique, Gmyr, Valéry, Raverdy, Violeta, Hubert, Thomas, Bonner, Caroline, Supiot, Lisa, Kerleau, Clarisse, Blancho, Gilles, Branchereau, Julien, Karam, Georges, Chelghaf, Ismaël, Houzet, Aurélie, Giral, Magali, Garandeau, Claire, Dantal, Jacques, Le Mapihan, Kristell, Jannin, Arnaud, Hazzan, Marc, Caiazzo, Robert, Kerr-Conte, Julie, Vantyghem, Marie-Christine, Cantarovich, Diego, Pattou, François

“…In islet transplantation (ITx), primary graft function (PGF) or beta cell function measured early after last infusion is closely associated with long term…”
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Coxsackievirus-B4 Infection of Human Primary Pancreatic Ductal Cell Cultures Results in Impairment of Differentiation into Insulin-Producing Cells by Bertin, Antoine, Sane, Famara, Gmyr, Valery, Lobert, Delphine, Dechaumes, Arthur, Kerr-Conte, Julie, Pattou, François, Hober, Didier

“…Coxsackievirus-B4 (CV-B4) E2 can persist in the pancreatic ductal-like cells (Panc-1 cell line), which results in an impaired differentiation of these cells…”
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Effects of subtotal pancreatectomy and long‐term glucose and lipid overload on insulin secretion and glucose homeostasis in minipigs by Goutchtat, Rébecca, Quenon, Audrey, Clarisse, Manon, Delalleau, Nathalie, Coddeville, Anaïs, Gobert, Mathilde, Gmyr, Valéry, Kerr‐Conte, Julie, Pattou, François, Hubert, Thomas

“…Introduction Nowadays, there are no strong diabetic pig models, yet they are required for various types of diabetes research. Using cutting‐edge techniques, we…”
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Coxsackievirus-B4 Infection Can Induce the Expression of Human Endogenous Retrovirus W in Primary Cells by Dechaumes, Arthur, Bertin, Antoine, Sane, Famara, Levet, Sandrine, Varghese, Jennifer, Charvet, Benjamin, Gmyr, Valéry, Kerr-Conte, Julie, Pierquin, Justine, Arunkumar, Govindakarnavar, Pattou, François, Perron, Hervé, Hober, Didier

“…Human Endogenous Retrovirus W Envelope (HERV-W ENV) mRNA or protein can be found in peripheral blood mononuclear cells (PBMCs) and exocrine pancreas of…”
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Proglucagon-Derived Peptides Expression and Secretion in Rat Insulinoma INS-1 Cells by Acosta-Montalvo, Ana, Saponaro, Chiara, Kerr-Conte, Julie, Prehn, Jochen H. M., Pattou, François, Bonner, Caroline

“…Rat insulinoma INS-1 cells are widely used to study insulin secretory mechanisms. Studies have shown that a population of INS-1 cells are bi-hormonal,…”
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1,25-Dihydroxyvitamin D3 Protects RINm5F and Human Islet Cells against Cytokine-Induced Apoptosis: Implication of the Antiapoptotic Protein A20 by Riachy, Rita, Vandewalle, Brigitte, Kerr Conte, Julie, Moerman, Ericka, Sacchetti, Paola, Lukowiak, Bruno, Gmyr, Valery, Bouckenooghe, Thomas, Dubois, Mathilde, Pattou, François

“…Transplantation of islets of Langerhans is a potential cure for type 1 diabetes, but its success is hampered by destruction of the islets. The data presented…”
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The microRNA-200 family regulates pancreatic beta cell survival in type 2 diabetes by Belgardt, Bengt-Frederik, Ahmed, Kashan, Spranger, Martina, Latreille, Mathieu, Denzler, Remy, Kondratiuk, Nadiia, von Meyenn, Ferdinand, Villena, Felipe Nunez, Herrmanns, Karolin, Bosco, Domenico, Kerr-Conte, Julie, Pattou, Francois, Rülicke, Thomas, Stoffel, Markus

“…The miR-200 family of miRNAs is upregulated in diabetes and leads to the apoptosis of pancreatic beta cells, while its knockout prevents this pathology…”
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GLP-1–Receptor Scanning for Imaging of Human Beta Cells Transplanted in Muscle by Pattou, Francois, Wild, Damian, Kerr-Conte, Julie

“…To the Editor: Cell therapy is emerging as a realistic treatment for type 1 diabetes, on the basis of the prolonged success of intraportal islet…”
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Long-Term GABA Administration Induces Alpha Cell-Mediated Beta-like Cell Neogenesis by Ben-Othman, Nouha, Vieira, Andhira, Courtney, Monica, Record, Fabien, Gjernes, Elisabet, Avolio, Fabio, Hadzic, Biljana, Druelle, Noémie, Napolitano, Tiziana, Navarro-Sanz, Sergi, Silvano, Serena, Al-Hasani, Keith, Pfeifer, Anja, Lacas-Gervais, Sandra, Leuckx, Gunter, Marroquí, Laura, Thévenet, Julien, Madsen, Ole Dragsbaek, Eizirik, Decio Laks, Heimberg, Harry, Kerr-Conte, Julie, Pattou, François, Mansouri, Ahmed, Collombat, Patrick

“…The recent discovery that genetically modified α cells can regenerate and convert into β-like cells in vivo holds great promise for diabetes research. However,…”
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