Search Results - "Kerr, Daniel A."
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Targeting 6-phosphofructo-2-kinase (PFKFB3) as a therapeutic strategy against cancer
Published in Molecular cancer therapeutics (01-08-2013)“…In human cancers, loss of PTEN, stabilization of hypoxia inducible factor-1α, and activation of Ras and AKT converge to increase the activity of a key…”
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Estradiol Stimulates Glucose Metabolism via 6-Phosphofructo-2-kinase (PFKFB3)
Published in The Journal of biological chemistry (28-03-2014)“…Estradiol (E2) administered to estrogen receptor-positive (ER+) breast cancer patients stimulates glucose uptake by tumors. Importantly, this E2-induced…”
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Abstract 3626: Day 21 early bone marrow response does not offer high concordance with response bone marrow in the induction chemotherapy setting of FLT3 mutant acute myeloid leukemia
Published in Cancer research (Chicago, Ill.) (22-03-2024)“…Purpose: Day 14 early bone marrow biopsies are routinely initiated to determine need for reinduction chemotherapy, but poorly predict true response and risk…”
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Journal Article