Search Results - "Kero, Mia"
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Lewy-related pathology exhibits two anatomically and genetically distinct progression patterns: a population-based study of Finns aged 85
Published in Acta neuropathologica (01-11-2019)“…According to a generally accepted concept Lewy-related pathology (LRP) follows hierarchical caudo-rostral progression. LRP is also frequently present…”
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2
Detection of microsatellite instability with Idylla MSI assay in colorectal and endometrial cancer
Published in Virchows Archiv : an international journal of pathology (01-09-2021)“…Universal testing of microsatellite instability (MSI) is recommended for colorectal cancer (CRC) and endometrial cancer (EC) to screen for Lynch syndrome and…”
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Alpha-synuclein pathology of olfactory bulbs/peduncles in the Vantaa85+ cohort exhibit two divergent patterns: a population-based study
Published in Acta neuropathologica (01-10-2021)Get full text
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Diagnostic performance of Idylla MSI test in colorectal cancer biopsies
Published in Diagnostic pathology (28-03-2023)“…Universal testing for microsatellite instability (MSI) is recommended in colorectal cancer (CRC) to screen for Lynch syndrome and to guide optimal treatment…”
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APOE ε4 associates with increased risk of severe COVID-19, cerebral microhaemorrhages and post-COVID mental fatigue: a Finnish biobank, autopsy and clinical study
Published in Acta neuropathologica communications (23-12-2021)“…Apolipoprotein E ε4 allele (APOE4) has been shown to associate with increased susceptibility to SARS-CoV-2 infection and COVID-19 mortality in some previous…”
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Aberrant expression of ALK and EZH2 in Merkel cell carcinoma
Published in BMC cancer (31-03-2017)“…Distinct characteristic features categorize Merkel cell carcinoma (MCC) into two subgroups according to the Merkel cell polyomavirus infection. Many mutational…”
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Gene fusions and oncogenic mutations in MLH1 deficient and BRAFV600E wild-type colorectal cancers
Published in Virchows Archiv : an international journal of pathology (01-04-2022)“…Gene fusions can act as oncogenic drivers and offer targets for cancer therapy. Since fusions are rare in colorectal cancer (CRC), their universal screening…”
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Amyloid precursor protein ( APP ) A673T mutation in the elderly Finnish population
Published in Neurobiology of aging (01-05-2013)“…Abstract Pathogenic mutations of the APP gene, leading to early-onset Alzheimer's disease (AD) have been known for more than 20 years. Recently, it was…”
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Hippocampal Sclerosis in the Oldest Old: A Finnish Population-Based Study
Published in Journal of Alzheimer's disease (01-01-2018)“…There are only few population-based studies that have systemically investigated the prevalence of hippocampal sclerosis (HS) in the very old. The frequency of…”
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10
Fatal Tick-Borne Encephalitis Virus Infections Caused by Siberian and European Subtypes, Finland, 2015
Published in Emerging infectious diseases (01-05-2018)“…In most locations except for Russia, tick-borne encephalitis is mainly caused by the European virus subtype. In 2015, fatal infections caused by European and…”
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Prediction models for dementia and neuropathology in the oldest old: the Vantaa 85+ cohort study
Published in Alzheimer's research & therapy (22-01-2019)“…We developed multifactorial models for predicting incident dementia and brain pathology in the oldest old using the Vantaa 85+ cohort. We included participants…”
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Distribution of Lewy-related pathology in the brain, spinal cord, and periphery: the population-based Vantaa 85 + study
Published in Acta neuropathologica communications (12-12-2022)“…Evolving evidence has supported the existence of two anatomically distinct Lewy-related pathology (LRP) types. Investigation of spinal cord and peripheral LRP…”
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13
ER,PR, HER2, Ki-67 and CK5 in Early and Late Relapsing Breast Cancer- Reduced CK5 Expression in Metastases
Published in Breast Cancer: Basic and Clinical Research (01-01-2013)“…Breast cancer can recur even decades after the primary therapy. Markers are needed to predict cancer progression and the risk of late recurrence. The estrogen…”
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GNEN-1: a spontaneously immortalized cell line from gastric neuroendocrine neoplasia
Published in Endocrine Connections (01-09-2021)“…Mixed neuroendocrine-non-neuroendocrine neoplasms (MINEN) are rare tumors that consist of at least 30% of both neuroendocrine and non-neuroendocrine…”
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ALK and EGFR expression by immunohistochemistry are associated with Merkel cell polyomavirus status in Merkel cell carcinoma
Published in Histopathology (01-05-2019)“…Aims Merkel cell carcinoma, a rare cutaneous neuroendocrine tumour of the skin, can be categorised into two groups according to Merkel cell polyomavirus (MCV)…”
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Limbic-predominant age-related TDP-43 encephalopathy in the oldest old: a population-based study
Published in Brain (London, England : 1878) (28-06-2024)“…Population-based cohort studies are essential for understanding the pathological basis of dementia in older populations. Previous studies have shown that…”
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Machine-learning–driven biomarker discovery for the discrimination between allergic and irritant contact dermatitis
Published in Proceedings of the National Academy of Sciences - PNAS (29-12-2020)“…Contact dermatitis tremendously impacts the quality of life of suffering patients. Currently, diagnostic regimes rely on allergy testing, exposure…”
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Frequency of LATE neuropathologic change across the spectrum of Alzheimer’s disease neuropathology: combined data from 13 community-based or population-based autopsy cohorts
Published in Acta neuropathologica (01-07-2022)“…Limbic-predominant age-related TDP-43 encephalopathy neuropathologic change (LATE-NC) and Alzheimer’s disease neuropathologic change (ADNC) are each associated…”
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Primary age‐related tauopathy in a Finnish population‐based study of the oldest old (Vantaa 85+)
Published in Neuropathology and applied neurobiology (01-04-2022)“…Aims Few studies have investigated primary age‐related tauopathy (PART) in a population‐based setting. Here, we assessed its prevalence, genetic background,…”
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Amygdala α-Synuclein Pathology in the Population-Based Vantaa 85+ Study
Published in Journal of Alzheimer's disease (01-01-2017)“…We investigated the frequency of Lewy-related pathology (LRP) in the amygdala among the population-based Vantaa 85+ study. Data of amygdala samples (N = 304)…”
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