Search Results - "Kernt, M."

Endophthalmitis: Pathogenesis, clinical presentation, management, and perspectives by Kernt, M, Kampik, A

“…Endophthalmitis is a rare but sight-threatening complication that can occur after ocular surgery or trauma or as a consequence of systemic infection. To…”
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Corneal biomechanics predict the outcome of selective laser trabeculoplasty in medically uncontrolled glaucoma by Hirneiß, Christoph, Sekura, K., Brandlhuber, U., Kampik, A., Kernt, M.

“…Purpose To evaluate the predictive value of clinical parameters, including biomechanical properties on the outcome of selective laser trabeculoplasty (SLT) in…”
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Twelve-month experience with Ozurdex for the treatment of macular edema associated with retinal vein occlusion by Mayer, W J, Wolf, A, Kernt, M, Kook, D, Kampik, A, Ulbig, M, Haritoglou, C

“…Purpose To evaluate the efficacy and safety of a dexamethasone implant (Ozurdex) alone or in combination with bevacizumab. Methods Sixty-four eyes were…”
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Intracameral voriconazole: In vitro safety for human ocular cells by Kernt, M, Kampik, A

“…Abstract Fungal keratitis is a sight-threatening infection of the cornea. It sometimes leads to loss of the eye. Despite an expanding range of fungal…”
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Attenuation of human lens epithelial cell spreading, migration and contraction via downregulation of the PI3K/Akt pathway by Liegl, R., Wertheimer, C., Kernt, M., Docheva, D., Kampik, A., Eibl-Lindner, K. H.

“…Background Posterior capsule opacification (PCO) represents a major challenge in the postoperative management of cataract patients. Spreading, migration and…”
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Intraocular caspofungin: in vitro safety profile for human ocular cells by Kernt, M., Kampik, A.

“…Summary Endogenous Candida endophthalmitis is sight‐threatening, difficult to treat and sometimes leads to loss of the eye. Only a few therapeutic agents are…”
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EGFR-Blockade With Erlotinib Reduces EGF and TGF-β2 Expression and the Actin-Cytoskeleton Which Influences Different Aspects of Cellular Migration in Lens Epithelial cells by Wertheimer, C., Liegl, R., Kernt, M., Docheva, D., Kampik, A., Eibl-Lindner, K.H.

“…Abstract Introduction: After cataract surgery, residual lens epithelial cells migrate and proliferate within the capsular bag resulting in posterior capsule…”
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EGF receptor inhibitor erlotinib as a potential pharmacological prophylaxis for posterior capsule opacification by Wertheimer, C., Liegl, R., Kernt, M., Mayer, W., Docheva, D., Kampik, A., Eibl-Lindner, K. H.

“…Background Posterior capsule opacification (PCO) is the most frequent complication after cataract surgery, leading to a loss of sight if untreated. Erlotinib…”
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Sorafenib prevents human retinal pigment epithelium cells from light-induced overexpression of VEGF, PDGF and PlGF by Kernt, M, Neubauer, A S, Liegl, R G, Hirneiss, C, Alge, C S, Wolf, A, Ulbig, M W, Kampik, A

“…Cumulative light exposure is significantly associated with progression of age-related macular degeneration (AMD). Inhibition of vascular endothelial growth…”
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Response to Hernández-Martínez et al by Mayer, W J, Wolf, A, Kernt, M, Kook, D, Kampik, A, Ulbig, M, Haritoglou, C

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Response to Hernandez-Martinez et al by Mayer, W J, Wolf, A, Kernt, M, Kook, D, Kampik, A, Ulbig, M, Haritoglou, C

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Significance of ophthalmological imaging in common hereditary retinal diseases by Kortüm, K, Kernt, M, Reznicek, L

“…Over the past years, a significant progress in genetic, functional and imaging diagnostics in hereditary retinal diseases has been made. Optical coherence…”
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Multikinase inhibitors as a new approach in neovascular age-related macular degeneration (AMD) treatment: in vitro safety evaluations of axitinib, pazopanib and sorafenib for intraocular use by Thiele, S, Liegl, R G, König, S, Siedlecki, J, Langer, J, Eibl, K, Haritoglou, C, Kampik, A, Kernt, M

“…Multikinase inhibitors (MKI) interfere effectively at different levels of the neovascularisation cascade. Early clinical and experimental data suggest that…”
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Sorafenib protects human optic nerve head astrocytes from light-induced overexpression of vascular endothelial growth factor, platelet-derived growth factor, and placenta growth factor by Kernt, M., Liegl, R. G., Rueping, J., Neubauer, A. S., Haritoglou, C., Lackerbauer, C. A., Eibl, K. H., Ulbig, M. W., Kampik, A.

“…Objectives: Growth factors, such as vascular endothelial growth factor (VEGF), platelet-derived growth factor (PDGF), and placenta growth factor (PlGF) are key…”
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Improvement of fixation in diabetic macular oedema patients under intravitreal ranibizumab treatment by Seidensticker, F, Reznicek, L, Cserhati, S, Liegl, R G, Langer, J, Wolf, A, Kampik, A, Ulbig, M, Haritoglou, C, Kernt, M

“…The aim of this study was to evaluate the fixation and other functional and morphological alterations in patients with diabetic macular oedema (DMO) under…”
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The role of light in the developement of RPE degeneration in AMD and potential cytoprotection of minocycline by Kernt, M, Thiele, S, Hirneiss, C, Neubauer, A S, Lackerbauer, C-A, Ulbig, M W, Kampik, A

“…Light-induced oxidative stress is an suggested reason for retinal pigment epithelium (RPE) degeneration in age-related macular degeneration (AMD). This study…”
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Combination of ranibizumab and navigated retinal photocoagulation in diabetic macular edema, compared to ranibizumab mono‐therapy: Twelve month results by KERNT, M

“…Purpose To evaluate the number of anti‐VEGF injections needed in DME patients using a protocol with navigated laser Methods A consecutive series of 76 eyes…”
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Diabetic maculopathy by Haritoglou, C, Kernt, M, Wolf, A

“…Diabetic maculopathy is the result of multifactorial and complex alterations of the retinal capillaries in association with diabetes mellitus and is divided…”
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Differences in the measurement results of Goldmann applanation tonometry with and without fluorescein by Arend, N, Hirneiss, C, Kernt, M

“…Goldmann applanation tonometry (GAT) is still the gold standard for measuring the intraocular pressure (IOP). Usually fluorescein eye drops are used additional…”
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A randomized placebo-controlled trial of idebenone in Leber's hereditary optic neuropathy by Klopstock, Thomas, Yu-Wai-Man, Patrick, Dimitriadis, Konstantinos, Rouleau, Jacinthe, Heck, Suzette, Bailie, Maura, Atawan, Alaa, Chattopadhyay, Sandip, Schubert, Marion, Garip, Aylin, Kernt, Marcus, Petraki, Diana, Rummey, Christian, Leinonen, Mika, Metz, Günther, Griffiths, Philip G., Meier, Thomas, Chinnery, Patrick F.

“…Major advances in understanding the pathogenesis of inherited metabolic disease caused by mitochondrial DNA mutations have yet to translate into treatments of…”
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