Search Results - "Kerns, J"
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Mechanism of Quinolone Action and Resistance
Published in Biochemistry (Easton) (18-03-2014)“…Quinolones are one of the most commonly prescribed classes of antibacterials in the world and are used to treat a variety of bacterial infections in humans…”
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2
Unmanned Aircraft Capture and Control Via GPS Spoofing
Published in Journal of field robotics (01-07-2014)“…The theory and practice of unmanned aerial vehicle (UAV) capture and control via Global Positioning System (GPS) signal spoofing are analyzed and demonstrated…”
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3
Crystal structure and stability of gyrase–fluoroquinolone cleaved complexes from Mycobacterium tuberculosis
Published in Proceedings of the National Academy of Sciences - PNAS (16-02-2016)“…Mycobacterium tuberculosis (Mtb) infects one-third of the world’s population and in 2013 accounted for 1.5 million deaths. Fluoroquinolone antibacterials,…”
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4
Development and validation of a weather-based warning system to advise fungicide applications to control dollar spot on turfgrass
Published in PloS one (09-03-2018)“…Dollar spot is one of the most common diseases of golf course turfgrass and numerous fungicide applications are often required to provide adequate control…”
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5
Fluoroquinolone interactions with Mycobacterium tuberculosis gyrase: Enhancing drug activity against wild-type and resistant gyrase
Published in Proceedings of the National Academy of Sciences - PNAS (16-02-2016)“…Mycobacterium tuberculosis is a significant source of global morbidity and mortality. Moxifloxacin and other fluoroquinolones are important therapeutic agents…”
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6
Topoisomerase IV-quinolone interactions are mediated through a water-metal ion bridge: mechanistic basis of quinolone resistance
Published in Nucleic acids research (01-04-2013)“…Although quinolones are the most commonly prescribed antibacterials, their use is threatened by an increasing prevalence of resistance. The most common causes…”
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Public Quality Reporting and Nursing Home Admission Decisions
Published in Journal of the American Medical Directors Association (01-12-2022)Get full text
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8
Role of the Water-Metal Ion Bridge in Quinolone Interactions with Escherichia coli Gyrase
Published in International journal of molecular sciences (02-02-2023)“…Fluoroquinolones are an important class of antibacterials, and rising levels of resistance threaten their clinical efficacy. Gaining a more full understanding…”
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Trends in Antiseizure Medication Prescribing Among Nursing Home Residents With and Without a Seizure Diagnosis
Published in The Neurologist (Baltimore, Md.) (01-09-2023)“…Evaluate current prevalence and changes in prescribing of antiseizure medications (ASMs) in Virginia nursing homes for residents with and without seizures…”
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10
Developmental profiling of microRNAs in the human embryonic inner ear
Published in PloS one (26-01-2018)“…Due to the extreme inaccessibility of fetal human inner ear tissue, defining of the microRNAs (miRNAs) that regulate development of the inner ear has relied on…”
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Lessons learned from CMS's National Partnership to Improve Dementia Care: a thematic synthesis of multiple stakeholder‐engaged studies
Published in Psychogeriatrics (01-09-2024)“…Background Antipsychotic prescribing in United States nursing homes (NHs) has decreased since the Center for Medicare & Medicaid Service debuted the National…”
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Community, Social, and Facility Factors and Long-stay Antipsychotic Use
Published in Clinical gerontologist (20-10-2022)“…Compare Virginia nursing homes in the top- and bottom-quintiles of antipsychotic use for variation in community, social, and facility factors. 2018 CMS data…”
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13
Fitness Attributes of Pythium aphanidermatum with Dual Resistance to Mefenoxam and Fenamidone
Published in Plant disease (01-10-2018)“…Pythium aphanidermatum is the predominant species causing Pythium root rot on commercially grown poinsettias in North Carolina. Resistance to mefenoxam is…”
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Second-trimester abortion attitudes and practices among maternal-fetal medicine and family planning subspecialists
Published in BMC women's health (03-02-2020)“…Patients deciding to undergo dilation and evacuation (D&E) or induction abortion for fetal anomalies or complications may be greatly influenced by the…”
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Soil surfactants influence fungicide movement in United States Golf Association putting green soil
Published in Journal of environmental quality (01-03-2020)“…The management of root and crown diseases of turfgrasses is challenging. To manage these diseases, golf course superintendents and other turfgrass managers…”
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Increased Reporting of Exclusionary Diagnoses Inflate Apparent Reductions in Long-Stay Antipsychotic Prescribing
Published in Clinical gerontologist (27-05-2019)“…Objective: Over the two years following the 2012 introduction of CMS's National Partnership, combined rates of schizophrenia, Tourette's, and Huntington's in…”
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Primary Care Physician Perspectives about Antipsychotics and Other Medications for Symptoms of Dementia
Published in Journal of the American Board of Family Medicine (01-01-2018)“…Guidelines, policies, and warnings have been applied to reduce the use of medications for behavioral and psychological symptoms of dementia (BPSD). Because of…”
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Overcoming Target-Mediated Quinolone Resistance in Topoisomerase IV by Introducing Metal-Ion-Independent Drug–Enzyme Interactions
Published in ACS chemical biology (20-12-2013)“…Quinolones, which target gyrase and topoisomerase IV, are the most widely prescribed antibacterials worldwide. Unfortunately, their use is threatened by the…”
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Lethal synergy involving bicyclomycin: an approach for reviving old antibiotics
Published in Journal of antimicrobial chemotherapy (01-12-2014)“…One way to address the growing problem of antimicrobial resistance is to revive old compounds that may have intrinsic lethal activity that is obscured by…”
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Understanding Long-Stay Gabapentin Use Increases: A National Nursing Home Clinician Survey on Prescribing Intent
Published in Clinical gerontologist (19-10-2024)“…Explore the indications for long-stay gabapentin use and elucidate the factors spurring the rapid increase in gabapentin prescribing in nursing homes (NHs)…”
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