Search Results - "Kernohan, Neil M."

Multimodality Characterization of Cancer-Associated Fibroblasts in Tumor Microenvironment and Its Correlation With Ultrasound Shear Wave-Measured Tissue Stiffness in Localized Prostate Cancer by Ageeli, Wael, Zhang, Xinyu, Ogbonnaya, Chidozie N, Bray, Susan E, Kernohan, Neil M, Wilson, Jennifer, Li, Chunhui, Nabi, Ghulam

“…Growing evidence suggests that the tumor microenvironment (TME) represented by cellular and acellular components plays a key role in the multistep process of…”
Get full text

An unusual extranodal T-cell non-Hodgkin lymphoma by Coats, Josh T, MRCP, Mackie, Alasdair D R, MD, Kernohan, Neil M, PhD, Ramkumar, Prasad Guntur, FRCR, McMahon, Lesley M, PhD, Goodlad, John R, MD, Tauro, Sudhir, Dr

“…A 32-year-old woman was admitted to our unit in April, 2015, with a 2-week history of back and loin pain, heaviness in her thighs, intermittent fever and…”
Get full text

Erythematous Macular Eruption in an Older Woman by McLaughlin, David, Kernohan, Neil M, Tauro, Sudhir

Get more information

The amino-acid stress sensing eIF2α kinase GCN2 is a survival biomarker for malignant mesothelioma by Gold, Lyssa T, Bray, Susan E, Kernohan, Neil M, Henderson, Nina, Nowicki, Maisie, Masson, Glenn R

“…Malignant mesothelioma is a tumour that is strongly associated with a history of asbestos exposure, and which derives from mesothelial cells that line the…”
Get full text

Gene expression in colorectal neoplasia: modifications induced by tissue ischaemic time and tissue handling protocol by Bray, Susan E, Paulin, Fiona E M, Fong, Siew Chinn, Baker, Lee, Carey, Frank A, Levison, David A, Steele, Robert J C, Kernohan, Neil M

“…Bray S E, Paulin F E M, Fong S C, Baker L, Carey F A, Levison D A, Steele R J C & Kernohan N M
(2010) Histopathology56, 240–250 Gene expression in colorectal…”
Get full text

Seliciclib (CYC202, R‐roscovitine) enhances the antitumor effect of doxorubicin in vivo in a breast cancer xenograft model by Appleyard, Maria Virginia C.L., O'Neill, Mary A., Murray, Karen E., Paulin, Fiona E.M., Bray, Susan E., Kernohan, Neil M., Levison, David A., Lane, David P., Thompson, Alastair M.

“…We sought to determine whether seliciclib (CYC202, R‐roscovitine) could increase the antitumor effects of doxorubicin, with no increase in toxicity, in an MCF7…”
Get full text

Overexpression and poly-ubiquitylation of the DEAD-box RNA helicase p68 in colorectal tumours by CAUSEVIC, Mirsada, HISLOP, R. Gordon, KERNOHAN, Neil M, CAREY, Francis A, KAY, Richard A, STEELE, Robert J. C, FULLER-PACE, Frances V

“…The DEAD box RNA helicase, p68, is upregulated in exponentially growing cells and shows cell cycle-dependent changes in nuclear localization. Although some…”
Get full text

Lesions resembling Langerhans cell histiocytosis in association with other lymphoproliferative disorders: a reactive or neoplastic phenomenon? by Christie, Lesley J., Evans, Alan T., Bray, Susan E., Smith, Mark E.F., Kernohan, Neil M., Levison, David A., Goodlad, John R.

“…Langerhans cell histiocytosis (LCH) has been described in association with a variety of neoplasms preceding, after, or synchronous with the other tumor. In…”
Get full text

Mutations of APC, K-ras, and p53 are associated with specific chromosomal aberrations in colorectal adenocarcinomas by LESLIE, Amy, PRATT, Norman R, GILLESPIE, Karen, SALES, Mark, KERNOHAN, Neil M, SMITH, Gillian, WOLF, C. Roland, CAREY, Francis A, STEELE, Robert J. C

“…It is widely accepted that both large-scale chromosomal abnormalities and mutation of specific genes, such as APC, K-ras, and/or p53, occur in the majority of…”
Get full text

Signaling to p53: the use of phospho-specific antibodies to probe for in vivo kinase activation by Craig, Ashley L, Bray, Susan E, Finlan, Lee E, Kernohan, Neil M, Hupp, Ted R

“…Phospho-specific antibody technology has been recently adopted to study p53 phosphorylation both in vivo and in vitro. We have developed and carefully…”
Get more information

Alteration of glutathione S-transferase levels in Barrett's metaplasia compared to normal oesophageal epithelium by Cobbe, Sarah C, Scobie, Gillian C, Pohler, Elizabeth, Hayes, John D, Kernohan, Neil M, Dillon, John F

“…OBJECTIVEOesophageal cancer associated with the premalignant condition Barrett's oesophagus has increased in incidence over the last few years. Phase II…”
Get full text

Activity of MDI-301, a novel synthetic retinoid, in xenografts by Appleyard, Virginia C. L, OʼNeill, Mary A, Murray, Karen E, Bray, Susan E, Thomson, George, Kernohan, Neil M, Varani, James, Zhang, Jian, Thompson, Alastair M

“…The efficacy of MDI-301, a non-toxic novel synthetic retinoid, was found to be equivalent to the natural 9-cis-retinoic acid (RA) in vitro against…”
Get full text

Modification of an N-terminal Regulatory Domain of T Antigen Restores p53-T Antigen Complex Formation in the Absence of an Essential Metal Ion Cofactor by Kernohan, N M, Hupp, T R, Lane, D P

“…We have discovered that the ability of the tumor suppressor protein p53 to bind to the viral large T antigen (TAg) oncogene product is regulated by divalent…”
Get full text

Expression of the p53 homologue p63α and ΔNp63α in normal and neoplastic cells by HALL, P. A, CAMPBELL, S. J, O'NEILL, M, ROYSTON, D. J, NYLANDER, K, CAREY, F. A, KERNOHAN, N. M

Get full text

Chromosomal imbalances in gastric and esophageal adenocarcinoma: Specific comparative genomic hybridization-detected abnormalities segregate with junctional adenocarcinomas by Stocks, S. Craig, Pratt, Norman, Sales, Mark, Johnston, David A., Thompson, Alastair M., Carey, Francis A., Kernohan, Neil M.

“…The incidence of adenocarcinoma arising at the esophagogastric junction (EGJ) is increasing at a rate greater than that for any other form of solid malignancy…”
Get full text

Surgical aspects of subungual malignant melanomas by PARK, K. G. M, BLESSING, K, KERNOHAN, N. M

Get full text

EDITORIAL. REGULATION OF APOPTOSIS BY Bcl-2 AND ITS RELATED PROTEINS: IMMUNOCHEMICAL CHALLENGES AND THERAPEUTIC IMPLICATIONS by KERNOHAN, NEIL M., COX, LYNNE S.

Get full text

Expression of the p53 homologue p63α and ΔNp63α in normal and neoplasticcells by Hall, Peter A., Campbell, Sandra J., O'neill, Mary, Royston, Daniel J., Nylander, Karin, Carey, Frank A., Kernohan, Neil M.

“…A burgeoning family of p53-related genes have been described recently, including p73 and p63. Both these genes encode proteins with many similarities to p53…”
Get full text