Search Results - "Kern, Simone"
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Employment status in multiple sclerosis: impact of disease-specific and non-disease-specific factors
Published in Multiple sclerosis (01-11-2013)“…Background: Multiple sclerosis (MS) is associated with high rates of early retirement (ER). Objectives: A German cohort of MS patients and healthy control…”
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Structural Elucidation of Trace Components Combining GC/MS, GC/IR, DFT‐Calculation and Synthesis—Salinilactones, Unprecedented Bicyclic Lactones from Salinispora Bacteria
Published in Angewandte Chemie International Edition (05-11-2018)“…The analysis of volatiles released by marine Salinispora bacteria uncovered a new class of natural compounds displaying an unusual bicyclic [3.1.0]‐lactone…”
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Cortisol awakening response is linked to disease course and progression in multiple sclerosis
Published in PloS one (16-04-2013)“…Dysregulation of the hypothalamus-pituitary-adrenal (HPA) axis has frequently been reported in multiple sclerosis (MS). So far, HPA axis function in MS has…”
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Fatigue and Sleep in Multiple Sclerosis Patients: A Comparison of Self-Report and Performance-Based Measures
Published in Frontiers in neurology (04-01-2018)“…Multiple sclerosis (MS) patients suffer very often from MS fatigue and sleep problems. Despite the detrimental impact on the activities of daily living, a…”
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First total synthesis of piperodione and analogs
Published in Tetrahedron letters (05-11-2014)“…[Display omitted] •A convenient synthesis of piperodione has been developed.•The synthesis of piperodione is very short and provides high yields.•Key steps of…”
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Effects of glatiramer acetate on fatigue and days of absence from work in first-time treated relapsing-remitting multiple sclerosis
Published in Health and quality of life outcomes (05-09-2008)“…Treatment of multiple sclerosis patients with glatiramer acetate has been demonstrated a beneficial effect on disease activity. The objective of this…”
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Circadian regulation of cortisol after hippocampal damage in humans
Published in Biological psychiatry (1969) (01-11-2004)“…There is substantial evidence that the hippocampus (HC) regulates the activity of the hypothalamic-pituitary-adrenocortical (HPA) axis. Damage to the HC in…”
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Multi-component relaxation in clinically isolated syndrome: Lesion myelination may predict multiple sclerosis conversion
Published in NeuroImage clinical (01-01-2018)“…We performed a longitudinal case-control study on patients with clinically isolated syndrome (CIS) with the aid of quantitative whole-brain myelin imaging. The…”
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Psychoneuroimmunology--cross-talk between the immune and nervous systems
Published in Journal of neurology (01-05-2007)“…Psychoneuroimmunology is a relatively new field of study that investigates interactions between behaviour and the immune system, mediated by the endocrine and…”
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Clinical relevance of circadian melatonin release in relapsing-remitting multiple sclerosis
Published in Journal of molecular medicine (Berlin, Germany) (01-11-2019)“…A growing body of evidence indicates the role of melatonin (MT) in the pathogenesis of multiple sclerosis (MS): It modulates immune function, alleviates…”
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Time matters – Acute stress response and glucocorticoid sensitivity in early multiple sclerosis
Published in Brain, behavior, and immunity (01-10-2014)“…Abstract Objective Psychosocial stress has frequently been associated with disease activity and acute exacerbations in multiple sclerosis (MS). Despite this…”
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Glucose metabolic changes in the prefrontal cortex are associated with HPA axis response to a psychosocial stressor
Published in Psychoneuroendocrinology (01-05-2008)“…Summary The prefrontal cortex (PFC) has been well known for its role in higher order cognition, affect regulation and social reasoning. Although the precise…”
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Evidence-based patient information programme in early multiple sclerosis: a randomised controlled trial
Published in Journal of neurology, neurosurgery and psychiatry (01-04-2014)“…Objective To evaluate the efficacy of an evidence-based patient information programme aiming to increase informed choice in patients with early multiple…”
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Cortisol’s effects on hippocampal activation in depressed patients are related to alterations in memory formation
Published in Journal of psychiatric research (01-01-2011)“…Abstract Many investigators have hypothesized that brain response to cortisol is altered in depression. However, neural activation in response to exogenously…”
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Brain-immune communication psychoneuroimmunology of multiple sclerosis
Published in Multiple sclerosis (2008)“…The central nervous system (CNS) and the immune system are two extremely complex and highly adaptive systems. In the face of a real or anticipated threat, be…”
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Strukturaufklärung von Spurenkomponenten durch Kombination von GC/MS, GC/IR, DFT‐Simulationen und Synthese – Salinilactone, neuartige bicyclische Lactone aus Salinispora Bakterien
Published in Angewandte Chemie (05-11-2018)“…Die Analyse flüchtiger Verbindungen aus marinen Salinispora Bakterien führte zur Entdeckung einer neuen Klasse von Naturstoffen mit ungewöhnlichem…”
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Neurological disability, psychological distress, and health-related quality of life in MS patients within the first three years after diagnosis
Published in Multiple sclerosis (01-06-2009)“…Background Psychological distress and psychiatric co-morbidity are common in multiple sclerosis (MS) and is often associated with neurological disability as…”
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Strukturaufklärung von Spurenkomponenten durch Kombination von GC/MS, GC/IR, DFT‐Simulationen und Synthese – Salinilactone, neuartige bicyclische Lactone aus Salinispora Bakterien
Published in Angewandte Chemie (05-11-2018)“…Abstract Die Analyse flüchtiger Verbindungen aus marinen Salinispora Bakterien führte zur Entdeckung einer neuen Klasse von Naturstoffen mit ungewöhnlichem…”
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