Search Results - "Kern, Michael A"

Collaborative governance: The role of university centers, institutes, and programs by Kern, Michael A., Smutko, L. Steven

“…For almost four decades, universities have played a significant role in developing the field of collaborative governance in the United States, including the…”
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Cyclooxygenase-2 inhibition induces apoptosis signaling via death receptors and mitochondria in hepatocellular carcinoma by KERN, Michael A, HAUGG, Anke M, FRIESS, Helmut, STREMMEL, Wolfgang, KRAMMER, Peter H, SCHIRMACHER, Peter, MÜLLER, Martina, KOCH, Andreas F, SCHILLING, Tobias, BREUHAHN, Kai, WALCZAK, Henning, FLEISCHER, Binje, TRAUTWEIN, Christian, MICHALSKI, Christoph, SCHULZE-BERGKAMEN, Henning

“…Inhibition of cyclooxygenase (COX)-2 elicits chemopreventive and therapeutic effects in solid tumors that are coupled with the induction of apoptosis in tumor…”
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Expression and therapeutic relevance of heat-shock protein 90 in pancreatic endocrine tumors by Mayer, Philipp, Harjung, Andreas, Breinig, Marco, Fischer, Lars, Ehemann, Volker, Malz, Mona, Scherübl, Hans, Britsch, Sarah, Werner, Jens, Kern, Michael A, Bläker, Hendrik, Schirmacher, Peter, Bergmann, Frank

“…Pancreatic endocrine tumors (PET) represent a heterogenous group of neoplasms. Although surgical resection is considered a safe and effective treatment for…”
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Expression of L1CAM, COX-2, EGFR, c-KIT and Her2/neu in anaplastic pancreatic cancer: putative therapeutic targets? by Bergmann, Frank, Moldenhauer, Gerhard, Herpel, Esther, Gaida, Matthias M, Strobel, Oliver, Werner, Jens, Esposito, Irene, Müerköster, Susanne Sebens, Schirmacher, Peter, Kern, Michael A

“…Bergmann F, Moldenhauer G, Herpel E, Gaida M M, Strobel O, Werner J, Esposito I, Sebens Müerköster S, Schirmacher P & Kern M A
(2010) Histopathology56, 440–448…”
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The role of Epstein–Barr virus in acute and chronic hepatitis by Drebber, Uta, Kasper, Hans U., Krupacz, Joanna, Haferkamp, Katharina, Kern, Michael A., Steffen, Hans M., Quasdorff, Maria, zur Hausen, Axel, Odenthal, Margarete, Dienes, Hans P.

“…Epstein–Barr virus has a seroprevalence of more than 80% world wide and is known to be associated with hepatitis. However, little is known about the underlying…”
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Establishment, characterization and drug sensitivity testing in primary cultures of human thymoma and thymic carcinoma by Ehemann, Volker, Kern, Michael A., Breinig, Marco, Schnabel, Philipp A., Gunawan, Bastian, Schulten, Hans‐Jörg, Schlaeger, Christoph, Radlwimmer, Bernhard, Steger, Christina M., Dienemann, Hendrik, Lichter, Peter, Schirmacher, Peter, Rieker, Ralf J.

“…Thymomas and thymic carcinomas are peculiar epithelial tumors of the anterior mediastinum. They may show aggressive clinical behavior and are a paradigm for…”
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COX‐2 upregulation in thymomas and thymic carcinomas by Rieker, Ralf J., Joos, Stefan, Mechtersheimer, Gunhild, Blaeker, Hendrik, Schnabel, Philipp A., Morresi‐Hauf, Alicia, Hecker, Erich, Thomas, Michael, Dienemann, Hendrik, Schirmacher, Peter, Kern, Michael A.

“…The treatment of advanced stage thymomas and thymic carcinomas is a multimodal therapy. New therapeutic targets are currently under investigation, including…”
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Fundamental differences in the neural invasion behavior of pancreatic endocrine tumors: relevance for local recurrence rates? by Bergmann, Frank, MD, Ceyhan, Güralp O., MD, Rieker, Ralf J., MD, Esposito, Irene, MD, Fischer, Lars, MD, Herpel, Esther, MD, Friess, Helmut, MD, Schirmacher, Peter, MD, Kern, Michael A., MD

“…Summary Neural invasion represents an important prognostic factor in pancreatic cancer, and it is thought to be one of the main causes for the high rate of…”
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Expression and Mutational Status of PDGFR in Thymic Tumours by MEISTER, Michael, KAHL, Philip, RIEKER, Ralf J, MULEY, Thomas, MORRESI-HAUF, Alicia, SEBENING, Christian, KERN, Michael A, BREINIG, Marco, SCHNABEL, Philipp, DIENEMANN, Hendrik, SCHIRMACHER, Peter

“…Background: There is an ongoing search for new therapeutic targets in invasive non-resectable thymic tumours because of the low response rates in current…”
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Recurrent deletions at 6q in early age of onset non-HNPCC- and non-FAP-associated intestinal carcinomas. Evidence for a novel cancer susceptibility locus at 6q14-q22 by Bläker, Hendrik, Mechtersheimer, Gunhild, Sutter, Christian, Hertkorn, Christian, Kern, Michael A., Rieker, Ralf J., Penzel, Roland, Schirmacher, Peter, Kloor, Matthias

“…Hereditary intestinal cancers mainly occur in the framework of the familial adenomatous polyposis (FAP) and hereditary nonpolyposis colorectal cancer (HNPCC)…”
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Expression of inducible nitric oxide synthase and cyclooxygenase-2 in pancreatic adenocarcinoma: correlation with microvessel density by Kasper, Hans-U, Wolf, Hella, Drebber, Uta, Wolf, Helmut-K, Kern, Michael-A

“…Cyclooxygenases (COX) are key enzymes for conversion of arachidonic acid to prostaglandins. Nitric oxide synthase (NOS) is the enzyme responsible for formation…”
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Expression of c-Met in developing rat hippocampus: evidence for HGF as a neurotrophic factor for calbindin D-expressing neurons by Korhonen, Laura, Sjöholm, Ulrika, Takei, Nobuyuki, Kern, Michael A., Schirmacher, Peter, Castrén, Eero, Lindholm, Dan

“…Hepatocyte growth factor‐scatter factor (HGF) is expressed in different parts of the nervous system, and has been shown to exhibit neurotrophic activity. Here…”
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Creating and Implementing Diverse Development Strategies to Support Extension Centers and Programs by Page, Christopher S, Kern, Michael A

“…Declining government funding for higher education requires colleges and universities to seek alternative revenue streams, including through philanthropic…”
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Expression Pattern and Functional Relevance of Epidermal Growth Factor Receptor and Cyclooxygenase-2: Novel Chemotherapeutic Targets in Pancreatic Endocrine Tumors? by BERGMANN, Frank, BREINIG, Marco, FRIESS, Helmut, SCHIRMACHER, Peter, KERN, Michael A, HÖPFNER, Michael, RIEKER, Ralfj, FISCHER, Lars, KÖOHLER, Christian, ESPOSITO, Irene, KLEEFF, Jörg, HERPEL, Esther, EHEMANN, Volker

“…Pancreatic endocrine tumors represent morphologically and biologically heterogeneous neoplasms. Well-differentiated endocrine tumors (benign or of uncertain…”
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Mutational status of the epidermal growth factor receptor (EGFR) gene in thymomas and thymic carcinomas by Meister, Michael, Schirmacher, Peter, Dienemann, Hendrik, Mechtersheimer, Gunhild, Schnabel, Philipp A, Kern, Michael A, Herpel, Esther, Xu, Elizabeth C, Muley, Thomas, Thomas, Michael, Rieker, Ralf J

“…Abstract Epithelial tumours of the thymus (thymoma, thymic carcinoma) are rare tumours of the anterior mediastinum. Current treatment options of advanced stage…”
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KRAS, EGFR, PDGFR-α, KIT and COX-2 status in carcinoma showing thymus-like elements (CASTLE) by Veits, Lothar, Schupfner, Rupert, Hufnagel, Petra, Penzel, Roland, Freitag, Jens, Ströbel, Philipp, Kern, Michael A, Schröder, Sören, Neuhold, Nikolaus, Schmid, Kurt W, Schirmacher, Peter, Hartmann, Arndt, Rieker, Ralf J

“…CASTLE (Carcinoma showing thymus-like elements) is a rare malignant neoplasm of the thyroid resembling lymphoepithelioma-like and squamous cell carcinoma of…”
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Induction of Apoptosis by Celecoxib in Cell Culture: An Uncertain Role for Cyclooxygenase-2 by Kern, Michael A., Schirmacher, Peter, Schilling, Tobias, Müller, Martina

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Cyclooxygenase-2 (COX-2)--a therapeutic target in liver cancer? by Breinig, Marco, Schirmacher, Peter, Kern, Michael André

“…Targeting COX-2, a key-enzyme of the prostaglandin metabolism, for the treatment of cancer has been in the focus of researchers for about a decade. However,…”
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Molecular pathogenesis of human hepatocellular carcinoma by Kern, Michael A., Breuhahn, Kai, Schirmacher, Peter

“…Hepatocellular carcinoma (HCC) is one of the most frequent human cancers. This chapter focuses on the compilation of molecular and functional changes…”
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Improved ultrastructural resolution by a new re-embedding procedure for formaldehyde-fixed paraffin-embedded tissues by Steiner, Hans-Jörg, Peringer, Paul, Moser, Patrizia, Schmid, Thomas, Kern, Michael A, Steger, Christina M, Mikuz, Gregor, Rieker, Ralf J

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