Search Results - "Kern, Jeannine V."
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Knockdown of transactive response DNA-binding protein (TDP-43) downregulates histone deacetylase 6
Published in The EMBO journal (06-01-2010)“…TDP‐43 is an RNA/DNA‐binding protein implicated in transcriptional repression and mRNA processing. Inclusions of TDP‐43 are hallmarks of frontotemporal…”
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The kinesin-3, unc-104 regulates dendrite morphogenesis and synaptic development in Drosophila
Published in Genetics (Austin) (01-09-2013)“…Kinesin-based transport is important for synaptogenesis, neuroplasticity, and maintaining synaptic function. In an anatomical screen of neurodevelopmental…”
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Spastic paraplegia mutation N256S in the neuronal microtubule motor KIF5A disrupts axonal transport in a Drosophila HSP model
Published in PLoS genetics (01-11-2012)“…Hereditary spastic paraplegias (HSPs) comprise a group of genetically heterogeneous neurodegenerative disorders characterized by spastic weakness of the lower…”
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The KIF1A homolog Unc-104 is important for spontaneous release, postsynaptic density maturation and perisynaptic scaffold organization
Published in Scientific reports (27-03-2017)“…The kinesin-3 family member KIF1A has been shown to be important for experience dependent neuroplasticity. In Drosophila , amorphic mutations in the KIF1A…”
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The Drosophila KIF1A Homolog unc-104 Is Important for Site-Specific Synapse Maturation
Published in Frontiers in cellular neuroscience (05-09-2016)“…Mutations in the kinesin-3 family member KIF1A have been associated with hereditary spastic paraplegia (HSP), hereditary and sensory autonomic neuropathy type…”
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In vivo imaging of intact Drosophila larvae at sub-cellular resolution
Published in Journal of visualized experiments (10-09-2010)“…Recent improvements in optical imaging, genetically encoded fluorophores and genetic tools allowing efficient establishment of desired transgenic animal lines…”
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Correction: Spastic Paraplegia Mutation N256S in the Neuronal Microtubule Motor KIF5A Disrupts Axonal Transport in a HSP Model
Published in PLoS genetics (01-04-2013)Get full text
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The Drosophila KIF1A homolog unc-104 is important for site-specific active zone maturation
Published in Frontiers in cellular neuroscience (01-09-2016)“…Abstract Mutations in the kinesin-3 family member KIF1A have been associated with hereditary spastic paraplegia, hereditary sensory and autonomic neuropathy…”
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Correction: Spastic Paraplegia Mutation N256S in the Neuronal Microtubule Motor KIF5A Disrupts Axonal Transport in a Drosophila HSP Model
Published in PLoS genetics (15-04-2013)Get full text
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10
In vivo Imaging of Intact Drosophila Larvae at Sub-cellular Resolution
Published in Journal of visualized experiments (10-09-2010)Get full text
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