Search Results - "Kermer, P"
-
1
Anti‐contactin‐associated protein‐2 encephalitis: relevance of antibody titres, presentation and outcome
Published in European journal of neurology (01-01-2017)“…Background and purpose To clarify the relevance of titres of IgG antibodies against contactin‐associated protein‐2 (CASPR2) in diagnosing anti‐CASPR2…”
Get full text
Journal Article -
2
Apheresis therapies for NMOSD attacks: A retrospective study of 207 therapeutic interventions
Published in Neurology : neuroimmunology & neuroinflammation (01-11-2018)“…OBJECTIVETo analyze whether 1 of the 2 apheresis techniques, therapeutic plasma exchange (PE) or immunoadsorption (IA), is superior in treating neuromyelitis…”
Get full text
Journal Article -
3
Risk prediction of very early recurrence, death and progression after acute ischaemic stroke
Published in European journal of neurology (01-04-2013)“…Background and purpose Early recurrent strokes lead to extended hospitalization and high number of complications. We investigated three stroke scores, the…”
Get full text
Journal Article -
4
Aggregopathy in neurodegenerative diseases: mechanisms and therapeutic implication
Published in Neuro-degenerative diseases (01-01-2008)“…Many neurodegenerative diseases such as Parkinson's, Alzheimer's, Huntington's and Lou Gehrig's disease are associated with the misfolding and aggregation of…”
Get more information
Journal Article -
5
-
6
Cerebellar-type multiple system atrophy presenting with leucoencephalopathy
Published in Journal of neurology, neurosurgery and psychiatry (01-02-2012)“…[...]a signal reflects an imbalance between free and tissue bound fluid and is indicative of leucoencephalopathy. [...]we instigated repeated…”
Get full text
Journal Article -
7
Mutant SOD1 detoxification mechanisms in intact single cells
Published in Cell death and differentiation (01-02-2008)“…Mutant superoxide dismutase 1 (mtSOD1) causes dominantly inherited amyotrophic lateral sclerosis (ALS). The mechanism for mtSOD1 toxicity remains unknown. Two…”
Get full text
Journal Article -
8
Bifunctional apoptosis inhibitor (BAR) protects neurons from diverse cell death pathways
Published in Cell death and differentiation (01-10-2003)“…The bifunctional apoptosis regulator (BAR) is a multidomain protein that was originally identified as an inhibitor of Bax-induced apoptosis. Immunoblot…”
Get full text
Journal Article -
9
Neuron-specific overexpression of the co-chaperone Bcl-2-associated athanogene-1 in superoxide dismutase 1(G93A)-transgenic mice
Published in Neuroscience (10-12-2008)“…Bcl-2-associated athanogene-1 (BAG1) binds heat-shock protein 70 (Hsp70)/Hsc70, increases intracellular chaperone activity in neurons and proved to be…”
Get full text
Journal Article -
10
Contribution of caspase-8 to apoptosis of axotomized rat retinal ganglion cells in vivo
Published in Neurobiology of disease (01-07-2003)“…We have investigated the role of caspase-8 and its mode of activation during apoptosis of adult rat retinal ganglion cells (RGCs) in vivo. Retinal…”
Get full text
Journal Article -
11
Neuron-specific overexpression of the co-chaperone Bcl-2-associated athanogene-1 in superoxide dismutase 1G93A –transgenic mice
Published in Neuroscience (01-12-2008)“…Abstract Bcl-2-associated athanogene-1 (BAG1) binds heat-shock protein 70 (Hsp70)/Hsc70, increases intracellular chaperone activity in neurons and proved to be…”
Get full text
Journal Article -
12
Bag1 is a regulator and marker of neuronal differentiation
Published in Cell death and differentiation (01-04-2002)“…Bag 1 acts as a co-chaperone for Hsp70/Hsc70. We report here that stable over-expression of Bag1 in immortalized neuronal CSM14.1 cells prevents death…”
Get full text
Journal Article -
13
Neuronal death after brain injury. Models, mechanisms, and therapeutic strategies in vivo
Published in Cell and tissue research (01-12-1999)“…Neuronal damage in the central nervous system leads to primary cell death, induced directly by the trauma, and delayed secondary death of neurons, the latter…”
Get full text
Journal Article -
14
Caspase-9: Involvement in secondary death of axotomized rat retinal ganglion cells in vivo
Published in Brain research. Molecular brain research. (28-12-2000)“…Recently we have shown that adult rat retinal ganglion cells (RGCs) die by apoptosis following optic nerve (ON) transection, activating caspase-3. In the…”
Get full text
Journal Article -
15
Evaluation of cerebral perfusion deficit in stroke patients using new transcranial contrast imaging CPS technology--preliminary results
Published in Ultraschall in der Medizin (01-12-2005)“…Contrast-enhanced transcranial duplex sonography can be used to examine cerebral perfusion. This technique, however, is still faced with methodological…”
Get more information
Journal Article -
16
Transduction of axotomized retinal ganglion cells by adenoviral vector administration at the optic nerve stump : an in vivo model system for the inhibition of neuronal apoptotic cell death
Published in Gene therapy (01-10-1999)“…Axotomy of the rat optic nerve leads to apoptotic cell death of retinal ganglion cells (RGCs). We have used adenoviral vectors to transduce RGCs from the cut…”
Get full text
Journal Article -
17
Fine structure of rat septohippocampal neurons. III. Recovery of choline acetyltransferase immunoreactivity after fimbria-fornix transection
Published in Journal of comparative neurology (1911) (08-12-1994)“…Most cholinergic projection neurons in the medial septal nucleus (MS) lose their capability to synthesize choline acetyltransferase (ChAT) after axotomy by…”
Get more information
Journal Article -
18
Final Study Report of Andexanet Alfa for Major Bleeding With Factor Xa Inhibitors
Published in Circulation (New York, N.Y.) (28-03-2023)“…Andexanet alfa is a modified recombinant inactive factor Xa (FXa) designed to reverse FXa inhibitors. ANNEXA-4 (Andexanet Alfa, a Novel Antidote to the…”
Get full text
Journal Article -
19
Fate of GABAergic septohippocampal neurons after fimbria-fornix transection as revealed by in situ hybridization for glutamate decarboxylase mRNA and parvalbumin immunocytochemistry
Published in Journal of comparative neurology (1911) (20-11-1995)“…Many septohippocampal neurons are GABAergic and are affected by transection of the fimbria-fornix, like the septohippocampal cholinergic cells. Here we have…”
Get more information
Journal Article -
20
Elsberg syndrome due to infarction of the conus medullaris associated with a prothrombin mutation
Published in Journal of neurology (01-06-1999)Get full text
Journal Article