Search Results - "Kepe, V"

In vitro detection of ( S)-naproxen and ibuprofen binding to plaques in the Alzheimer’s brain using the positron emission tomography molecular imaging probe 2-(1-{6-[(2-[ 18F]fluoroethyl)(methyl)amino]-2-naphthyl}ethylidene)malononitrile by Agdeppa, E.D, Kepe, V, Petri, A, Satyamurthy, N, Liu, J, Huang, S.-C, Small, G.W, Cole, G.M, Barrio, J.R

“…Epidemiological studies have suggested that the chronic use of non-steroidal anti-inflammatory drugs (NSAIDs) reduces the relative risk of Alzheimer’s disease…”
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Binding Characteristics of Radiofluorinated 6-Dialkylamino-2-Naphthylethylidene Derivatives as Positron Emission Tomography Imaging Probes for beta -Amyloid Plaques in Alzheimer's Disease by Agdeppa, Eric D, Kepe, Vladimir, Liu, Jie, Flores-Torres, Samuel, Satyamurthy, Nagichettiar, Petric, Andrej, Cole, Greg M, Small, Gary W, Huang, Sung-Cheng, Barrio, Jorge R

“…Senile plaques (SPs) and neurofibrillary tangles (NFTs) are hallmark pathologies accompanying the neurodegeneration involved in Alzheimer's disease (AD), for…”
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Amyloid imaging in distinguishing atypical prion disease from Alzheimer disease by BOXER, A. L, RABINOVICI, G. D, SMALL, G. W, BARRIO, J. R, JAGUST, W, MILLER, B. L, KEPE, V, GOLDMAN, J, FURST, A. J, HUANG, S.-C, BAKER, S. L, O'NEIL, J. P, CHUI, H, GESCHWIND, M. D

“…To compare the in vivo uptake of two amyloid-binding PET agents, PIB and FDDNP, in human subjects with a prion protein (PrP) gene (PRNP) mutation that produces…”
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FDDNP binding using MR derived cortical surface maps by Protas, H.D., Huang, S.-C., Kepe, V., Hayashi, K., Klunder, A., Braskie, M.N., Ercoli, L., Bookheimer, S., Thompson, P.M., Small, G.W., Barrio, J.R.

“…To assess quantitatively the cortical pattern profile of regional FDDNP binding to beta-amyloid and neurofibrillary tangles on MR derived cortical maps, FDDNP…”
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Assessment of dementia risk in aging adults using both FDG-PET and FDDNP-PET imaging by Ercoli, L. M., Small, G. W., Siddarth, P., Kepe, V., Huang, S.-C., Miller, K. J., Lavretsky, H., Bookheimer, S. Y., Barrio, J. R., Silverman, D. H. S.

“…Background In a previous study, positron emission tomography (PET) with 2‐(1‐{6‐[(2‐[F‐18]fluoroethyl)(methyl)amino]‐2‐naphthyl}ethylidene)malononitrile…”
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Amyloid and tau imaging, neuronal losses and function in mild cognitive impairment by Barrio, J. R., Kepe, V., Satyamurthy, N., Huang, S. C., Small, G.

“…Objectives : Establish new approaches for early diagnosis of dementia, based on imaging amyloid and tau pathology, cell losses and neuronal function, in…”
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Amyloid and tau imaging, neuronal losses and function in mild cognitive impairment by Barrio, J.R., Kepe, V., Satyamurthy, N., Huang, S.C., Small, G.

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Depression and anxiety symptoms are associated with cerebral FDDNP-PET binding in middle-aged and older non-demented adults by Lavretsky, H, Siddarth, P, Kepe, V, Ercoli, L, Miller, K, Bookheimer, S, Huang, H, Barrio, J, Small, G

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Correlation of Cortical Thickness Within the Medial Temporal Lobe to PET Measures of Brain Amyloid and Tau by Burggren, AC, Martin-Harris, L, Suthana, NS, Donix, M, Ekstrom, AD, Jones, M, Renner, B, Kepe, V, Huang, S-C, Barrio, J, Ercoli, LM, Miller, KJ, Siddarth, P, Small, GW, Bookheimer, SY

“…Introduction Our lab has shown differences in cortical thickness in medial temporal lobe (MTL) subregions in cognitively intact apolipoprotein E-4 (APOE-4)…”
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Exploring a mathematical model for the kinetics of beta-amyloid molecular imaging probes through a critical analysis of plaque pathology by Shoghi-Jadid, Kooresh, Barrio, Jorge R, Kepe, Vladimir, Huang, Sung-Cheng

“…Amyloid plaques are highly heterogeneous in content, size, density, and macromolecular crowding, as they are composed of masses of fibrils and other cellular…”
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In vivo brain imaging of tangle burden in humans by Small, Gary W, Agdeppa, Eric D, Kepe, Vladimir, Satyamurthy, Nagichettiar, Huang, Sung-Cheng, Barrio, Jorge R

“…Cerebral neurofibrillary tangles (NFTs) accumulate in a predictable sequence decades before the clinical symptoms of Alzheimer's disease emerge, and the degree…”
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Abnormal protein aggregation in the brains of long-term surviving HIV patients in the HAART era by Achim, CL, Barrio, J R, Kepe, V, Everall, I P, Masliah, E, Smid, A, Cherner, M, Taylor, MJ, Vinters, H V, Pomakian, J, Satyamurthy, N, von Jaeger, R, Small, G W, Grant, I

“…Background: Human immunodeficiency virus (HIV) positive patients under highly active anti-retroviral therapy (HAART) regimens show a markedly improved general…”
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In vitro detection of (S)-naproxen and ibuprofen binding to plaques in the Alzheimer's brain using the positron emission tomography molecular imaging probe 2-(1-[6-[(2-[(18)F]fluoroethyl)(methyl)amino]-2-naphthyl]ethylidene)malononitrile by Agdeppa, E D, Kepe, V, Petri, A, Satyamurthy, N, Liu, J, Huang, S-C, Small, G W, Cole, G M, Barrio, J R

“…Epidemiological studies have suggested that the chronic use of non-steroidal anti-inflammatory drugs (NSAIDs) reduces the relative risk of Alzheimer's disease…”
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Evaluation of two graphical approaches for regional analysis and parametric mapping of dynamic [18F]FDDNP PET studies by Koon-Pong Wong, Sung-Cheng Huang, Kepe, V., Small, G.W., Barrio, J.R.

“…Positron emission tomography (PET) with 2-(1-{6-[(2-[ 18 F]fluoroethyl)(methyl)amino]-2-naphthyl}ethylidene)malo-nonitrile ([ 18 F]FDDNP) has been used for in…”
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Comparison of simplified methods for quantitative analysis of [18F]FDDNP PET data by Koon-Pong Wong, Kepe, V., Small, G.W., Satyamurthy, N., Barrio, J.R., Sung-Cheng Huang

“…Positron emission tomography (PET) with 2-(1-{6- [(2-[ 18 F]fluoroethyl)(methyl)amino]-2-naphthyl}ethylidene)malo-nonitrile ([ 18 F]FDDNP) has been used for in…”
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Movement correction of [18F]FDDNP PET studies for brain amyloid imaging by Koon-Pong Wong, Wardak, M., Weber Shao, Zicong Zhou, Dahlbom, M., Smid, L., Truong, D., Kepe, V., Small, G.W., Barrio, J.R., Sung-Cheng Huang

“…2-(l-{6-[(2-[18F]fluoroethyl)(methyl)amino]-2-naph- thyl}ethylidene)malononitrile ([ 18 F]FDDNP) PET studies for imaging neuronal concentration of beta-amyloid…”
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In vitro and in vivo binding characteristics of two biological probes for plaques and tangles in alzheimer's disease by Agdeppa, E. D., Kepe, V., Liu, J., Shoghi-Jadid, K., Satyamurthy, N., Small, G. W., Petric, A., Vinters, H. V., Huang, S. C., Barrio, J. R.

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4-Ethoxymethylene-2-phenyl-5-(4H)-oxazolone as a synthon for the synthesis of some fused pyrimidines by KEPE, V, KOCEVAR, M, POLANC, S

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4-Ethoxymethylene-2-phenyl-5(4H)-oxazolone as a synthon for the synthesis of some 2H-pyran-2-ones by KEPE, V, KOCEVAR, M, PETRIC, A, POLANC, S, VERCEK, B

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