Search Results - "Kenyon, Emma"

Low genotypic diversity and long-term ecological decline in a spatially structured seagrass population by Alotaibi, Nahaa M., Kenyon, Emma J., Cook, Kevan J., Börger, Luca, Bull, James C.

“…In isolated or declining populations, viability may be compromised further by loss of genetic diversity. Therefore, it is important to understand the…”
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Editorial: Model systems in hearing research by Kenyon, Emma J, Warren, Ben, Mittal, Rahul, Hashino, Eri

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Design, Synthesis, and Biological Evaluation of a New Series of Carvedilol Derivatives That Protect Sensory Hair Cells from Aminoglycoside-Induced Damage by Blocking the Mechanoelectrical Transducer Channel by O’Reilly, Molly, Kirkwood, Nerissa K, Kenyon, Emma J, Huckvale, Rosemary, Cantillon, Daire M, Waddell, Simon J, Ward, Simon E, Richardson, Guy P, Kros, Corné J, Derudas, Marco

“…Aminoglycosides (AGs) are broad-spectrum antibiotics used for the treatment of serious bacterial infections but have use-limiting side effects including…”
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Environment predicts seagrass genotype, phenotype, and associated biodiversity in a temperate ecosystem by Alotaibi, Nahaa M, Kenyon, Emma J, Bertelli, Chiara M, Al-Qthanin, Rahmah N, Mead, Jessica, Parry, Mark, Bull, James C

“…Coastal vegetative ecosystems are among the most threatened in the world, facing multiple anthropogenic stressors. A good example of this is seagrass, which…”
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Functional analysis of conserved non-coding regions around the short stature hox gene (shox) in whole zebrafish embryos by Kenyon, Emma J, McEwen, Gayle K, Callaway, Heather, Elgar, Greg

“…Mutations in the SHOX gene are responsible for Leri-Weill Dyschondrosteosis, a disorder characterised by mesomelic limb shortening. Recent investigations into…”
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Local competition and metapopulation processes drive long-term seagrass-epiphyte population dynamics by Lobelle, Delphine, Kenyon, Emma J, Cook, Kevan J, Bull, James C

“…It is well known that ecological processes such as population regulation and natural enemy interactions potentially occur over a range of spatial scales, and…”
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d-Tubocurarine and Berbamine: Alkaloids That Are Permeant Blockers of the Hair Cell's Mechano-Electrical Transducer Channel and Protect from Aminoglycoside Toxicity by Kirkwood, Nerissa K, O'Reilly, Molly, Derudas, Marco, Kenyon, Emma J, Huckvale, Rosemary, van Netten, Sietse M, Ward, Simon E, Richardson, Guy P, Kros, Corné J

“…Aminoglycoside antibiotics are widely used for the treatment of life-threatening bacterial infections, but cause permanent hearing loss in a substantial…”
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Wasting disease regulates long-term population dynamics in a threatened seagrass by Bull, James C., Kenyon, Emma J., Cook, Kevan J.

“…The role of disease in the long-term dynamics of threatened species is poorly quantified, as well as being under-represented in ecology and conservation…”
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The roles of flowering, overwinter survival and sea surface temperature in the long-term population dynamics of Zostera marina around the Isles of Scilly, UK by Potouroglou, Maria, Kenyon, Emma J., Gall, Angie, Cook, Kevan J., Bull, James C.

“…•We present long-term eelgrass flowering shoot data from the Isles of Scilly, UK.•Flowering is highly structured in time and space, increasing with sea…”
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Identification of a series of hair-cell MET channel blockers that protect against aminoglycoside-induced ototoxicity by Kenyon, Emma J, Kirkwood, Nerissa K, Kitcher, Siân R, Goodyear, Richard J, Derudas, Marco, Cantillon, Daire M, Baxendale, Sarah, de la Vega de León, Antonio, Mahieu, Virginia N, Osgood, Richard T, Wilson, Charlotte Donald, Bull, James C, Waddell, Simon J, Whitfield, Tanya T, Ward, Simon E, Kros, Corné J, Richardson, Guy P

“…To identify small molecules that shield mammalian sensory hair cells from the ototoxic side effects of aminoglycoside antibiotics, 10,240 compounds were…”
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Charge and lipophilicity are required for effective block of the hair-cell mechano-electrical transducer channel by FM1-43 and its derivatives by Derudas, Marco, O’Reilly, Molly, Kirkwood, Nerissa K., Kenyon, Emma J., Grimsey, Sybil, Kitcher, Siân R., Workman, Shawna, Bull, James C., Ward, Simon E., Kros, Corné J., Richardson, Guy P.

“…The styryl dye FM1-43 is widely used to study endocytosis but behaves as a permeant blocker of the mechano-electrical transducer (MET) channel in sensory hair…”
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Zebrafish Rab5 proteins and a role for Rab5ab in nodal signalling by Kenyon, Emma J., Campos, Isabel, Bull, James C., Williams, P. Huw, Stemple, Derek L., Clark, Matthew D.

“…The RAB5 gene family is the best characterised of all human RAB families and is essential for in vitro homotypic fusion of early endosomes. In recent years,…”
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Identification of ion-channel modulators that protect against aminoglycoside-induced hair cell death by Kenyon, Emma J, Kirkwood, Nerissa K, Kitcher, Siân R, O'Reilly, Molly, Derudas, Marco, Cantillon, Daire M, Goodyear, Richard J, Secker, Abigail, Baxendale, Sarah, Bull, James C, Waddell, Simon J, Whitfield, Tanya T, Ward, Simon E, Kros, Corné J, Richardson, Guy P

“…Aminoglycoside antibiotics are used to treat life-threatening bacterial infections but can cause deafness due to hair cell death in the inner ear. Compounds…”
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Expression and knockdown of zebrafish folliculin suggests requirement for embryonic brain morphogenesis by Kenyon, Emma J, Luijten, Monique N H, Gill, Harmeet, Li, Nan, Rawlings, Matthew, Bull, James C, Hadzhiev, Yavor, van Steensel, Maurice A M, Maher, Eamonn, Mueller, Ferenc

“…Birt-Hogg-Dubé syndrome (BHD) is a dominantly inherited familial cancer syndrome characterised by the development of benign skin fibrofolliculomas, multiple…”
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Long-term effects of ovariectomy and estrogen replacement treatment on endothelial function in mature rats by Moien-Afshari, Farzad, Kenyon, Emma, Choy, Jonathan C., Battistini, Bruno, McManus, Bruce M., Laher, Ismail

“…Objectives: Estrogen replacement therapy (ERT) improves blood flow through various mechanisms including an augmented release of nitric oxide (NO). We report on…”
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The roles of flowering, overwinter survival and sea surface temperature in the long-term population dynamics of Zostera marina around the Isles of Scilly, UK: Seagrass meadows in a globally changing environment by POTOUROGLOU, Maria, KENYON, Emma J, GALL, Angie, COOK, Kevan J, BULL, James C

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Functional Analysis of Conserved Non-Coding Regions Around the Short Stature hox Gene by Kenyon, Emma J, McEwen, Gayle K, Callaway, Heather, Elgar, Greg

“…Background Mutations in the SHOX gene are responsible for Leri-Weill Dyschondrosteosis, a disorder characterised by mesomelic limb shortening. Recent…”
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Correction: Corrigendum: The zebrafish reference genome sequence and its relationship to the human genome by Howe, Kerstin, Clark, Matthew D., Torroja, Carlos F., Torrance, James, Collins, John E., Humphray, Sean, McLaren, Karen, Matthews, Lucy, McLaren, Stuart, Sealy, Ian, Caccamo, Mario, Churcher, Carol, Rauch, Gerd-Jörg, White, Simon, Gu, Yong, Yen, Jennifer, Vogel, Jan-Hinnerk, Banerjee, Ruby, Langley, Elizabeth, Maguire, Sean F., Laird, Gavin, Lloyd, David, Donaldson, Sarah, Almeida-King, Jeff, Trevanion, Stephen, Jones, Matt, Quail, Mike, Hunt, Adrienne, Davis, Joy, Clee, Chris, Oliver, Karen, Clark, Richard, Elliott, David, Threadgold, Glen, Harden, Glenn, Ware, Darren, Begum, Sharmin, Heath, Paul, Tracey, Alan, Corby, Nicole, Dunn, Matthew, Wood, Jonathan, Glithero, Rebecca, Howden, Philip, Barker, Nicholas, Holt, Karen, Panagiotidis, Georgios, Beasley, Helen, Henderson, Carl, Gordon, Daria, Wright, Deborah, Dyer, Lauren, Leung, Kenric, Gilderthorp, Ruth, Griffiths, Coline, Manthravadi, Deepa, Nichol, Sarah, Whitehead, Siobhan, Kay, Michael, Brown, Jacqueline, Murnane, Clare, Sycamore, Neil, Barker, Darren, Wallis, Justene, Hammond, Sian, Mashreghi-Mohammadi, Maryam, Barr, Lucy, Martin, Sancha, Wray, Paul, Ellington, Andrew, Matthews, Nicholas, Ellwood, Matthew, Woodmansey, Rebecca, Grafham, Darren, Pandian, Richard, Kimberley, Andrew, Garnett, Jane, Kelly, Daniel, Palmer, Sophie, Berger, Andrea, Dooley, Christopher, Karotki, Lena, Konantz, Martina, Oberländer, Martina, Rudolph-Geiger, Silke, Teucke, Mathias, Lanz, Christa, Osoegawa, Kazutoyo, Yang, Fengtang, Schuster, Stephan C., Carter, Nigel P., Harrow, Jennifer, Herrero, Javier, Searle, Steve M. J., Geisler, Robert, de Jong, Pieter J., Postlethwait, John H., Volhard, Christiane Nüsslein, Crollius, Hugues Roest, Rogers, Jane

“…Nature 496, 498–503 (2013); doi:10.1038/nature12111 In this Letter, five authors were inadvertently omitted: Sharmin Begum and Christine Lloyd from the…”
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Erratum: Corrigendum: The zebrafish reference genome sequence and its relationship to the human genome by Howe, Kerstin, Clark, Matthew D., Torroja, Carlos F., Torrance, James, Berthelot, Camille, Muffato, Matthieu, Collins, John E., Humphray, Sean, McLaren, Karen, Matthews, Lucy, McLaren, Stuart, Sealy, Ian, Caccamo, Mario, Churcher, Carol, Scott, Carol, Barrett, Jeffrey C., Koch, Romke, Rauch, Gerd-Jörg, White, Simon, Chow, William, Kilian, Britt, Quintais, Leonor T., Guerra-Assunção, José A., Zhou, Yi, Gu, Yong, Yen, Jennifer, Vogel, Jan-Hinnerk, Eyre, Tina, Banerjee, Ruby, Chi, Jianxiang, Fu, Beiyuan, Langley, Elizabeth, Maguire, Sean F., Laird, Gavin, Lloyd, David, Kenyon, Emma, Donaldson, Sarah, Sehra, Harminder, Almeida-King, Jeff, Loveland, Jane, Trevanion, Stephen, Jones, Matt, Quail, Mike, Willey, Dave, Hunt, Adrienne, Burton, John, Sims, Sarah, McLay, Kirsten, Plumb, Bob, Davis, Joy, Clee, Chris, Oliver, Karen, Clark, Richard, Riddle, Clare, Elliott, David, Threadgold, Glen, Harden, Glenn, Ware, Darren, Begum, Sharmin, Mortimore, Beverley, Kerry, Giselle, Heath, Paul, Phillimore, Benjamin, Tracey, Alan, Corby, Nicole, Dunn, Matthew, Johnson, Christopher, Wood, Jonathan, Clark, Susan, Pelan, Sarah, Griffiths, Guy, Smith, Michelle, Glithero, Rebecca, Howden, Philip, Barker, Nicholas, Lloyd, Christine, Stevens, Christopher, Harley, Joanna, Holt, Karen, Panagiotidis, Georgios, Lovell, Jamieson, Beasley, Helen, Henderson, Carl, Gordon, Daria, Auger, Katherine, Wright, Deborah, Collins, Joanna, Raisen, Claire, Dyer, Lauren, Leung, Kenric, Robertson, Lauren, Ambridge, Kirsty, Leongamornlert, Daniel, McGuire, Sarah, Gilderthorp, Ruth, Griffiths, Coline, Manthravadi, Deepa, Nichol, Sarah, Barker, Gary, Whitehead, Siobhan

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Investigations into the Rab family of genes and their roles in signalling during vertebrate early development by Kenyon, Emma Jane

“…The mammalian Rab family consists of between 60-70 members, making it the largest sub family of the Ras superfamily. Rabs are responsible for vesicle…”
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