Search Results - "Kentish, Stephen J."
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Time-Restricted Feeding Prevents Ablation of Diurnal Rhythms in Gastric Vagal Afferent Mechanosensitivity Observed in High-Fat Diet-Induced Obese Mice
Published in The Journal of neuroscience (30-05-2018)“…Mechanosensitive gastric vagal afferents (GVAs) are involved in the regulation of food intake. GVAs exhibit diurnal rhythmicity in their response to…”
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TRPV1 Channels and Gastric Vagal Afferent Signalling in Lean and High Fat Diet Induced Obese Mice
Published in PloS one (18-08-2015)“…Within the gastrointestinal tract vagal afferents play a role in control of food intake and satiety signalling. Activation of mechanosensitive gastric vagal…”
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A novel role for the extracellular matrix glycoprotein‐Tenascin‐X in gastric function
Published in The Journal of physiology (01-03-2019)“…Key points Tenascin X (TNX) functions in the extracellular matrix of skin and joints where it maintains correct intercellular connections and tissue…”
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Gastric vagal afferent modulation by leptin is influenced by food intake status
Published in The Journal of physiology (01-04-2013)“…Key points • Obesity occurs when energy intake exceeds expenditure, and the excess energy is stored as fat. • We show that, after a 14 h food deprivation or…”
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The role of gastrointestinal vagal afferent fibres in obesity
Published in The Journal of physiology (15-02-2015)“…Gastrointestinal (GI) vagal afferents are a key mediatory of food intake. Through a balance of responses to chemical and mechanical stimuli food intake can be…”
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Vagal KATP channels are the key to ghrelin's orexigenic action
Published in The Journal of physiology (15-10-2015)Get full text
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High-Fat Diet-Induced Obesity Ablates Gastric Vagal Afferent Circadian Rhythms
Published in The Journal of neuroscience (16-03-2016)“…Rats with high-fat diet (HFD)-induced obesity increase daytime eating, suggesting an alteration in circadian food intake mechanisms. Gastric vagal afferents…”
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Apelin modulates murine gastric vagal afferent mechanosensitivity
Published in Physiology & behavior (01-10-2018)“…Gastric vagal afferents play an important role in the peripheral control of food intake. Apelin, a central appetite regulating hormone, is also abundantly…”
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Pregnancy-related plasticity of gastric vagal afferent signals in mice
Published in American journal of physiology: Gastrointestinal and liver physiology (01-02-2021)“…Gastric vagal afferents (GVAs) sense food-related mechanical stimuli and signal to the central nervous system, to integrate control of meal termination…”
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Plasticity of gastro-intestinal vagal afferent endings
Published in Physiology & behavior (01-09-2014)“…Abstract Vagal afferents are a vital link between the peripheral tissue and central nervous system (CNS). There is an abundance of vagal afferents present…”
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Journal Article Conference Proceeding -
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Nesfatin-1 modulates murine gastric vagal afferent mechanosensitivity in a nutritional state dependent manner
Published in Peptides (New York, N.Y. : 1980) (01-03-2017)“…•Nesfatin-1 potentiated mucosal receptor mechanosensitivity in lean fed and fasted but not high fat diet (HFD) mice.•Tension receptor mechanosensitivity was…”
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Disruption of the light cycle ablates diurnal rhythms in gastric vagal afferent mechanosensitivity
Published in Neurogastroenterology and motility (01-12-2019)“…Background Gastric vagal afferents (GVAs) respond to mechanical stimulation, initiating satiety. These afferents exhibit diurnal fluctuations in…”
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Circadian variation in gastric vagal afferent mechanosensitivity
Published in The Journal of neuroscience (04-12-2013)“…Food intake is coordinated to cellular metabolism by clock gene expression with a master clock in the suprachiasmatic nucleus synchronized by light exposure…”
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High fat diet induced changes in gastric vagal afferent response to adiponectin
Published in Physiology & behavior (01-12-2015)“…Abstract Food intake is regulated by vagal afferent signals from the stomach. Adiponectin, secreted primarily from adipocytes, also has a role in regulating…”
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Caspase-2 deficiency enhances whole-body carbohydrate utilisation and prevents high-fat diet-induced obesity
Published in Cell death & disease (01-10-2017)“…Caspase-2 has been shown to be involved in metabolic homeostasis. Here, we show that caspase-2 deficiency alters basal energy metabolism by shifting the…”
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Diet‐dependent modulation of gastro‐oesphageal vagal afferent mechanosensitivity by endogenous nitric oxide
Published in The Journal of physiology (01-08-2014)“…Key points Nitric oxide (NO) is an important signalling molecule found in the gastrointestinal tract, which can modulate the mechanosensitivity of…”
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A chronic high fat diet alters the homologous and heterologous control of appetite regulating peptide receptor expression
Published in Peptides (New York, N.Y. : 1980) (01-08-2013)“…•Investigation of appetite hormone regulation of vagal afferent receptor expression.•Leptin, ghrelin and NPW have the ability to modulate their own and other…”
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Neuropeptide W modulation of gastric vagal afferent mechanosensitivity: Impact of age and sex
Published in Peptides (New York, N.Y. : 1980) (01-09-2015)“…•NPW inhibits gastric vagal afferent tension receptors in 20 but not 8-week-old mice.•NPW inhibits gastric vagal afferent mucosal receptors in 8 but not…”
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Sa1400 Daily Rhythm of Gastric Vagal Afferent Mechanosensitivity and Satiety Signaling
Published in Gastroenterology (New York, N.Y. 1943) (01-05-2012)Get full text
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Vagal leptin signalling: A double agent in energy homeostasis?
Published in Molecular metabolism (Germany) (01-09-2014)Get full text
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