Search Results - "Kent, Robert N."

New parameters describing how knee ligaments carry force in situ predict interspecimen variations in laxity during simulated clinical exams by Imhauser, Carl W., Kent, Robert N., Boorman-Padgett, James, Thein, Ran, Wickiewicz, Thomas L., Pearle, Andrew D.

“…Knee laxity, defined as the net translation or rotation of the tibia relative to the femur in a given direction in response to an applied load, is highly…”
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Engineered Microenvironmental Cues from Fiber‐Reinforced Hydrogel Composites Drive Tenogenesis and Aligned Collagen Deposition by Kent, Robert N., Jewett, Maggie E., Buck, Trevor P., Said, Mohamed, Hold, LeeAnn A., Crawford, Eileen A., Killian, Megan L., Abraham, Adam C., Huang, Alice H., Baker, Brendon M.

“…Effective tendon regeneration following injury is contingent on appropriate differentiation of recruited cells and deposition of mature, aligned, collagenous…”
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Building‐Block Size Mediates Microporous Annealed Particle Hydrogel Tube Microenvironment Following Spinal Cord Injury by Ross, Brian C., Kent, Robert N., Saunders, Michael N., Schwartz, Samantha R., Smiley, Brooke M., Hocevar, Sarah E., Chen, Shao‐Chi, Xiao, Chengchuan, Williams, Laura A., Anderson, Aileen J., Cummings, Brian J., Baker, Brendon M., Shea, Lonnie D.

“…Spinal cord injury (SCI) is a life‐altering event, which often results in loss of sensory and motor function below the level of trauma. Biomaterial therapies…”
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Engagement of the Secondary Ligamentous and Meniscal Restraints Relative to the Anterior Cruciate Ligament Predicts Anterior Knee Laxity by Kent, Robert N., Imhauser, Carl W., Thein, Ran, Marom, Niv, Wickiewicz, Thomas L., Nawabi, Danyal H., Pearle, Andrew D.

“…Background: Patients with high-grade preoperative side-to-side differences in anterior laxity as assessed via the Lachman test after unilateral anterior…”
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Direct comparison of angiogenesis in natural and synthetic biomaterials reveals that matrix porosity regulates endothelial cell invasion speed and sprout diameter by Wang, William Y., Kent, Robert N., Huang, Stephanie A., Jarman, Evan H., Shikanov, Eve H., Davidson, Christopher D., Hiraki, Harrison L., Lin, Daphne, Wall, Monica A., Matera, Daniel L., Shin, Jae-Won, Polacheck, William J., Shikanov, Ariella, Baker, Brendon M.

“…Vascularization of large, diffusion-hindered biomaterial implants requires an understanding of how extracellular matrix (ECM) properties regulate angiogenesis…”
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Ultrasound-generated bubbles enhance osteogenic differentiation of mesenchymal stromal cells in composite collagen hydrogels by Maji, Somnath, Aliabouzar, Mitra, Quesada, Carole, Chiravuri, Anjali, Macpherson, Aidan, Pinch, Abigail, Kazyak, Karsyn, Emara, Ziyad, Abeid, Bachir A., Kent, Robert N., Midekssa, Firaol S., Zhang, Man, Baker, Brendon M., Franceschi, Renny T., Fabiilli, Mario L.

“…Hydrogels can improve the delivery of mesenchymal stromal cells (MSCs) by providing crucial biophysical cues that mimic the extracellular matrix. The…”
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Augmentation of Tendon and Ligament Repair with Fiber‐Reinforced Hydrogel Composites by Kent, Robert N., Huang, Alice H., Baker, Brendon M.

“…This review highlights the promise of fiber‐reinforced hydrogel composites (FRHCs) for augmenting tendon and ligament repair and regeneration. Composed of…”
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Physical and Soluble Cues Enhance Tendon Progenitor Cell Invasion into Injectable Synthetic Hydrogels by Kent, Robert N., Said, Mohamed, Busch, Megan E., Poupard, Ethan R., Tsai, Ariane, Xia, Jingyi, Matera, Daniel L., Wang, William Y., DePalma, Samuel J., Hiraki, Harrison L., Killian, Megan L., Abraham, Adam C., Shin, Jae‐Won, Huang, Alice H., Shikanov, Ariella, Baker, Brendon M.

“…Synthetic hydrogels represent an exciting avenue in the field of regenerative biomaterials given their injectability, orthogonally tunable mechanical…”
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Discoidin domain receptor 2 regulates aberrant mesenchymal lineage cell fate and matrix organization by Pagani, Chase A, Bancroft, Alec C, Tower, Robert J, Livingston, Nicholas, Sun, Yuxiao, Hong, Jonathan Y, Kent, 3rd, Robert N, Strong, Amy L, Nunez, Johanna H, Medrano, Jessica Marie R, Patel, Nicole, Nanes, Benjamin A, Dean, Kevin M, Li, Zhao, Ge, Chunxi, Baker, Brendon M, James, Aaron W, Weiss, Stephen J, Franceschi, Renny T, Levi, Benjamin

“…Extracellular matrix (ECM) interactions regulate both the cell transcriptome and proteome, thereby determining cell fate. Traumatic heterotopic ossification…”
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Early Outcomes Following Plantar Condylectomy and Imbrication of Plantar Plate to Metatarsal Neck for Metatarsalgia and Grade 0 Lesser Toe Metatarsophalangeal Joint Instability by Kent, Robert N., Walley, Kempland C., Saunders, Noah, Colomb, Eric, Patel, Vandan, Holmes, James R., Walton, David M., Talusan, Paul G.

“…Background: Metatarsalgia and plantar plate tears are characterized by forefoot pain and toe deformity in severe cases. Conservative management may slow…”
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Tibiofemoral Kinematics During Compressive Loading of the ACL-Intact and ACL-Sectioned Knee: Roles of Tibial Slope, Medial Eminence Volume, and Anterior Laxity by Wang, Dean, Kent, Robert N., Amirtharaj, Mark J., Hardy, Brendan M., Nawabi, Danyal H., Wickiewicz, Thomas L., Pearle, Andrew D., Imhauser, Carl W.

“…Tibial geometry and knee laxity have been identified as risk factors for both noncontact anterior cruciate ligament (ACL) rupture and instability in the…”
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Automated, accurate, and three-dimensional method for calculating sagittal slope of the tibial plateau by Amirtharaj, Mark J., Hardy, Brendan M., Kent, Robert N., Nawabi, Danyal H., Wickiewicz, Thomas L., Pearle, Andrew D., Imhauser, Carl W.

“…Increased posterior-inferior directed slope of the subchondral bone of the lateral tibial plateau is a risk factor for noncontact rupture of the anterior…”
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Anterior laxity, lateral tibial slope, and in situ ACL force differentiate knees exhibiting distinct patterns of motion during a pivoting event: A human cadaveric study by Kent, Robert N., Amirtharaj, Mark J., Hardy, Brendan M., Pearle, Andrew D., Wickiewicz, Thomas L., Imhauser, Carl W.

“…Knee instability following anterior cruciate ligament (ACL) rupture compromises function and increases risk of injury to the cartilage and menisci. To…”
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Magnetic Alignment of Electrospun Fiber Segments Within a Hydrogel Composite Guides Cell Spreading and Migration Phenotype Switching by Hiraki, Harrison L, Matera, Daniel L, Rose, Michael J, Kent, Robert N, Todd, Connor W, Stout, Mark E, Wank, Anya E, Schiavone, Maria C, DePalma, Samuel J, Zarouk, Alexander A, Baker, Brendon M

“…Fibrous extracellular matrix (ECM) proteins provide mechanical structure and adhesive scaffolding to resident cells within stromal tissues. Aligned ECM fibers…”
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Degree of Tendon Retraction and Younger Age Are Associated With Functional Decline Following Nonoperative Management of Complete Proximal Hamstring Ruptures by deMeireles, Alirio J., Kent, Robert N., Bedi, Asheesh, Crawford, Eileen A.

“…To characterize functional outcomes of patients with complete proximal hamstring tendon ruptures who were treated nonoperatively and determine whether there…”
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Anterior cruciate ligament graft forces are sensitive to fixation angle and tunnel position within the native femoral footprint during passive flexion by Kent, Robert N., Amirtharaj, Mark J., Berube, Erin E., Imhauser, Carl W., Thein, Ran, Voleti, Pramod B., Wickiewicz, Thomas L., Pearle, Andrew D., Nawabi, Danyal H.

“…Anterior cruciate ligament (ACL) graft position within the anatomic femoral footprint of the native ACL and the flexion angle at which the graft is fixed…”
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High Interspecimen Variability in Engagement of the Anterolateral Ligament: An In Vitro Cadaveric Study by Kent, Robert N., Boorman-Padgett, James F., Thein, Ran, van der List, Jelle P., Nawabi, Danyal H., Wickiewicz, Thomas L., Imhauser, Carl W., Pearle, Andrew D.

“…Background Anterolateral ligament (ALL) reconstruction as an adjunct to anterior cruciate ligament (ACL) reconstruction remains a subject of clinical debate…”
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Surgical Imbrication of Plantar Plate to Metatarsal Neck in the Setting of Lesser Toe Metatarsophalangeal Joint Instability by Talusan, Paul G., Colomb, Eric, Kent, Robert N., Patel, Vandan D., Holmes, James R., Walton, David M.

“…Category: Lesser Toes; Midfoot/Forefoot Introduction/Purpose: Persistent metatarsalgia refractory to non-operative therapy with accompanying plantar plate…”
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Primary and coupled motions of the native knee in response to applied varus and valgus load by Gladnick, Brian P, Boorman-Padgett, James, Stone, Kyle, Kent, Robert N, Cross, Michael B, Mayman, David J, Pearle, Andrew D, Imhauser, Carl W

“…Abstract Background Knowledge of the complex kinematics of the native knee is a prerequisite for a successful reconstructive procedure. The aim of this study…”
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Erratum to: High Interspecimen Variability in Engagement of the Anterolateral Ligament: An In Vitro Cadaveric Study by Kent, Robert N., Boorman-Padgett, James F., Thein, Ran, van der List, Jelle P., Nawabi, Danyal H., Wickiewicz, Thomas L., Imhauser, Carl W., Pearle, Andrew D.

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