Search Results - "Kenski, Juliana C.N."
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Sulfated heterorhamnans from the green seaweed Gayralia oxysperma: partial depolymerization, chemical structure and antitumor activity
Published in Carbohydrate polymers (06-03-2015)“…•Smith-degraded polysaccharides were obtained from sulfated heterorhamnans.•The homogeneous fractions are highly sulfated and present Mwof 109 and…”
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Parallel In Vivo and In Vitro Melanoma RNAi Dropout Screens Reveal Synthetic Lethality between Hypoxia and DNA Damage Response Inhibition
Published in Cell reports (Cambridge) (20-11-2014)“…To identify factors preferentially necessary for driving tumor expansion, we performed parallel in vitro and in vivo negative-selection short hairpin RNA…”
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Augmenting Immunotherapy Impact by Lowering Tumor TNF Cytotoxicity Threshold
Published in Cell (25-07-2019)“…New opportunities are needed to increase immune checkpoint blockade (ICB) benefit. Whereas the interferon (IFN)γ pathway harbors both ICB resistance factors…”
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Reversal of pre-existing NGFR-driven tumor and immune therapy resistance
Published in Nature communications (07-08-2020)“…Melanomas can switch to a dedifferentiated cell state upon exposure to cytotoxic T cells. However, it is unclear whether such tumor cells pre-exist in patients…”
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Augmenting Immunotherapy Impact by Lowering Tumor TNF Cytotoxicity Threshold
Published in Cell (23-01-2020)Get full text
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An adverse tumor-protective effect of IDO1 inhibition
Published in Cell reports. Medicine (21-02-2023)“…By restoring tryptophan, indoleamine 2,3-dioxygenase 1 (IDO1) inhibitors aim to reactivate anti-tumor T cells. However, a phase III trial assessing their…”
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Flavone induces cell death in human hepatoma HepG2 cells
Published in Natural product communications (01-10-2014)“…Flavones have received considerable attention because of their antiproliferative properties and selective effects on cancer cells, making them good candidates…”
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