Search Results - "Kenny, K."

Fluorogenic DNA-PAINT for faster, low-background super-resolution imaging by Chung, Kenny K. H., Zhang, Zhao, Kidd, Phylicia, Zhang, Yongdeng, Williams, Nathan D., Rollins, Bennett, Yang, Yang, Lin, Chenxiang, Baddeley, David, Bewersdorf, Joerg

“…DNA-based points accumulation for imaging in nanoscale topography (DNA-PAINT) is a powerful super-resolution microscopy method that can acquire high-fidelity…”
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Alpha-synuclein impairs normal dynamics of mitochondria in cell and animal models of Parkinson's disease by Xie, Weilin, Chung, Kenny K. K.

“…J. Neurochem. (2012) 122, 404–414. Alpha‐synuclein (α‐syn) is a synaptic protein that mutations have been linked to Parkinson’s disease (PD), a common…”
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The role of alpha-synuclein oligomerization and aggregation in cellular and animal models of Parkinson's disease by Wan, Oi Wan, Chung, Kenny K K

“…α-Synuclein (α-syn) is a synaptic protein in which four mutations (A53T, A30P, E46K and gene triplication) have been found to cause an autosomal dominant form…”
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The role of polo‐like kinases 2 in the proteasomal and lysosomal degradation of alpha‐synuclein in neurons by Sung, Chun Chau, Lam, Wai Yun, Chung, Kenny K. K.

“…Parkinson's disease (PD) is a neurodegenerative disorder caused by the degeneration of dopaminergic neurons in the brain stem. PD is mostly sporadic, but…”
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S-Nitrosylation of G protein-coupled receptor kinase 6 and Casein kinase 2 alpha modulates their kinase activity toward alpha-synuclein phosphorylation in an animal model of Parkinson's disease by Wu, Weiwei, Sung, Chun Chau, Yu, Peichun, Li, Jiahua, Chung, Kenny K K

“…Parkinson's disease (PD) is a common neurodegenerative disorder which is mostly sporadic but familial-linked PD (FPD) cases have also been found. The first…”
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S-Nitrosylation of Parkin Regulates Ubiquitination and Compromises Parkin's Protective Function by Kenny K. K. Chung, Thomas, Bobby, Li, Xiaojie, Pletnikova, Olga, Troncoso, Juan C., Marsh, Laura, Dawson, Valina L., Dawson, Ted M.

“…Parkin is an E3 ubiquitin ligase involved in the ubiquitination of proteins that are important in the survival of dopamine neurons in Parkinson's disease (PD)…”
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The development of unit shaft resistance along driven piles in subsiding soil by Kania, Jakub G., Sørensen, Kenny K., Fellenius, Bengt H.

“…The influence of bitumen coating on the development of unit shaft resistance along driven steel and precast concrete piles resulting from subsiding surrounding…”
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Predicting mini-tablet dissolution performance utilizing X-ray computed tomography by Borjigin, Tohn, Zhan, Xi, Li, Jiangwei, Meda, Alvin, Tran, Kenny K.

“…•A workflow was developed utilizing X-ray microcomputed tomography and convolutional neural network-based image segmentation to image and obtain physical…”
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Fibrin-targeting immunotherapy protects against neuroinflammation and neurodegeneration by Ryu, Jae Kyu, Rafalski, Victoria A., Meyer-Franke, Anke, Adams, Ryan A., Poda, Suresh B., Rios Coronado, Pamela E., Pedersen, Lars Østergaard, Menon, Veena, Baeten, Kim M., Sikorski, Shoana L., Bedard, Catherine, Hanspers, Kristina, Bardehle, Sophia, Mendiola, Andrew S., Davalos, Dimitrios, Machado, Michael R., Chan, Justin P., Plastira, Ioanna, Petersen, Mark A., Pfaff, Samuel J., Ang, Kenny K., Hallenbeck, Kenneth K., Syme, Catriona, Hakozaki, Hiroyuki, Ellisman, Mark H., Swanson, Raymond A., Zamvil, Scott S., Arkin, Michelle R., Zorn, Stevin H., Pico, Alexander R., Mucke, Lennart, Freedman, Stephen B., Stavenhagen, Jeffrey B., Nelson, Robert B., Akassoglou, Katerina

“…Activation of innate immunity and deposition of blood-derived fibrin in the central nervous system (CNS) occur in autoimmune and neurodegenerative diseases,…”
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A screen against Leishmania intracellular amastigotes: comparison to a promastigote screen and identification of a host cell-specific hit by De Muylder, Geraldine, Ang, Kenny K H, Chen, Steven, Arkin, Michelle R, Engel, Juan C, McKerrow, James H

“…The ability to screen compounds in a high-throughput manner is essential in the process of small molecule drug discovery. Critical to the success of screening…”
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Translational Tomography with the Wide-field Imager for Parker Solar Probe (WISPR). II. Refinements to the Method by Kenny, K. N., DeForest, C. E., Van Kooten, S. J., Liewer, P. C.

“…Abstract We present progress on the translational tomography technique for measuring the three-dimensional structure of the corona from near-perihelion…”
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Image-Based High-Throughput Drug Screening Targeting the Intracellular Stage of Trypanosoma cruzi, the Agent of Chagas' Disease by Engel, Juan C, Ang, Kenny K H, Chen, Steven, Arkin, Michelle R, McKerrow, James H, Doyle, Patricia S

“…OA  Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Correction: S-Nitrosylation of G protein-coupled receptor kinase 6 and Casein kinase 2 alpha modulates their kinase activity toward alpha-synuclein phosphorylation in an animal model of Parkinson’s disease by Wu, Weiwei, Sung, Chun Chau, Yu, Peichun, Li, Jiahua, Chung, Kenny K. K

“…The samples were also subject to Western blot analysis of GRK6, CK2α, GAPDH, pSer129 α-syn and α-syn. (→: GRK6 band) (B) Quantification of hemizygous A53T…”
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Parkin Mediates Nonclassical, Proteasomal-Independent Ubiquitination of Synphilin-1: Implications for Lewy Body Formation by Lim, Kah Leong, Chew, Katherine C. M, Tan, Jeanne M. M, Wang, Cheng, Chung, Kenny K. K, Zhang, Yi, Tanaka, Yuji, Smith, Wanli, Engelender, Simone, Ross, Christopher A, Dawson, Valina L, Dawson, Ted M

“…It is widely accepted that the familial Parkinson's disease (PD)-linked gene product, parkin, functions as a ubiquitin ligase involved in protein turnover via…”
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IL-11 is a crucial determinant of cardiovascular fibrosis by Schafer, Sebastian, Viswanathan, Sivakumar, Widjaja, Anissa A., Lim, Wei-Wen, Moreno-Moral, Aida, DeLaughter, Daniel M., Ng, Benjamin, Patone, Giannino, Chow, Kingsley, Khin, Ester, Tan, Jessie, Chothani, Sonia P., Ye, Lei, Rackham, Owen J. L., Ko, Nicole S. J., Sahib, Norliza E., Pua, Chee Jian, Zhen, Nicole T. G., Xie, Chen, Wang, Mao, Maatz, Henrike, Lim, Shiqi, Saar, Kathrin, Blachut, Susanne, Petretto, Enrico, Schmidt, Sabine, Putoczki, Tracy, Guimarães-Camboa, Nuno, Wakimoto, Hiroko, van Heesch, Sebastiaan, Sigmundsson, Kristmundur, Lim, See L., Soon, Jia L., Chao, Victor T. T., Chua, Yeow L., Tan, Teing E., Evans, Sylvia M., Loh, Yee J., Jamal, Muhammad H., Ong, Kim K., Chua, Kim C., Ong, Boon-Hean, Chakaramakkil, Mathew J., Seidman, Jonathan G., Seidman, Christine E., Hubner, Norbert, Sin, Kenny Y. K., Cook, Stuart A.

“…Fibroblast-specific Il-11 expression causes heart and kidney fibrosis and organ failure, whereas IL-11 inhibition prevents fibroblast activation and organ…”
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The role of age‐associated alpha‐synuclein aggregation in a conditional transgenic mouse model of Parkinson's disease: Implications for Lewy body formation by Li, Jiahua, Ng, Ka Wai, Sung, Chun Chau, Chung, Kenny K. K.

“…Parkinson's disease (PD) is a common neurodegenerative disorder that is affecting an increasing number of older adults. Although PD is mostly sporadic, genetic…”
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Association between air pollution and general outpatient clinic consultations for upper respiratory tract infections in Hong Kong by Tam, Wilson W S, Wong, Tze Wai, Ng, Lorna, Wong, Samuel Y S, Kung, Kenny K L, Wong, Andromeda H S

“…Many studies have shown the adverse effects of air pollution on respiratory health, but few have examined the effects of air pollution on service utilisation…”
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Bariatric Surgery or Non-surgical Weight Loss for Idiopathic Intracranial Hypertension? A Systematic Review and Comparison of Meta-analyses by Manfield, James H., Yu, Kenny K-H., Efthimiou, Evangelos, Darzi, Ara, Athanasiou, Thanos, Ashrafian, Hutan

“…Background Idiopathic intracranial hypertension (IIH) is associated with obesity and weight loss by any means is considered beneficial in this condition…”
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Effect of the Poly(ethylene glycol) (PEG) Density on the Access and Uptake of Particles by Antigen-Presenting Cells (APCs) after Subcutaneous Administration by Zhan, Xi, Tran, Kenny K, Shen, Hong

“…Lymphatic trafficking of particles to the secondary lymphoid organs, such as lymph nodes, and the cell types that particles access are critical factors that…”
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Oxidative and nitrosative stress in Parkinson's disease by Tsang, Anthony H.K., Chung, Kenny K.K.

“…Parkinson's disease (PD) is a common neurodegenerative disorder marked by movement impairment caused by a selective degeneration of dopaminergic neurons. The…”
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