Search Results - "Kenney, Patrick M.J."

Benzyl isothiocyanate: an effective inhibitor of polycyclic aromatic hydrocarbon tumorigenesis in A/J mouse lung by Hecht, Stephen S, Kenney, Patrick M.J, Wang, Mingyao, Upadhyaya, Pramod

“…Polycyclic aromatic hydrocarbons (PAH) are an important group of carcinogens that are likely to be involved as one of the causes of lung cancer in smokers and…”
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Evaluation of butylated hydroxyanisole, myo-inositol, curcumin, esculetin, resveratrol and lycopene as inhibitors of benzo[ a]pyrene plus 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone-induced lung tumorigenesis in A/J mice by Hecht, Stephen S, Kenney, Patrick M.J, Wang, Mingyao, Trushin, Neil, Agarwal, Sanjiv, Venket Rao, A, Upadhyaya, Pramod

“…The potential activities of butylated hydroxyanisole (BHA), myo-inositol, curcumin, esculetin, resveratrol and lycopene-enriched tomato oleoresin (LTO) as…”
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Effects of phenethyl isothiocyanate and benzyl isothiocyanate, individually and in combination, on lung tumorigenesis induced in A/J mice by benzo[a]pyrene and 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone by HECHT, S. S, KENNEY, P. M. J, MINGYAO WANG, TRUSHIN, N, UPADHYAYA, P

“…Phenethyl isothiocyanate (PEITC) is an effective inhibitor of lung tumorigenesis induced in rats and mice by the tobacco-specific carcinogen…”
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Effects of Cruciferous Vegetable Consumption on Urinary Metabolites of the Tobacco-Specific Lung Carcinogen 4-(Methylnitrosamino)-1-(3-Pyridyl)-1-Butanone in Singapore Chinese by HECHT, Stephen S, CARMELLA, Steven G, KENNEY, Patrick M. J, LOW, Siew-Hong, ARAKAWA, Kazuko, YU, Mimi C

“…Vegetable consumption, including cruciferous vegetables, is protective against lung cancer, but the mechanisms are poorly understood. The purpose of this study…”
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Inhibition of lung tumorigenesis in A/J mice by N-acetyl-S-(N-2-phenethylthiocarbamoyl)-L-cysteine and myo-inositol, individually and in combination by Hecht, Stephen S., Upadhyaya, Pramod, Wang, Mingyao, Bliss, Robin L., McIntee, Edward J., Kenney, Patrick M.J.

“…Isothiocyanates, their N-acetylcysteine conjugates, and myo-inositol (MI) are inhibitors of lung tumorigenesis in A/J mice. However, chemoprevention by…”
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Effects of benzyl isothiocyanate and 2-phenethyl isothiocyanate on benzo[a]pyrene and 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone metabolism in F-344 rats by Boysen, Gunnar, Kenney, Patrick M.J., Upadhyaya, Pramod, Wang, Mingyao, Hecht, Stephen S.

“…A mixture of dietary benzyl isothiocyanate (BITC) and 2-phenethyl isothiocyanate (PEITC) inhibits lung tumorigenesis by a mixture of benzo[a]pyrene (B[a]P) and…”
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Effects of benzyl isothiocyanate and phenethyl isothiocyanate on DNA adduct formation by a mixture of benzo[a]pyrene and 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone in A/J mouse lung by Sticha, Kristina R.K., Kenney, Patrick M.J., Boysen, Gunnar, Liang, Hong, Su, Xiaojing, Wang, Mingyao, Upadhyaya, Pramod, Hecht, Stephen S.

“…Dietary phenethyl isothiocyanate (PEITC) and a mixture of dietary PEITC and benzyl isothiocyanate (BITC) inhibit lung tumorigenesis in A/J mice induced by a…”
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Effects of benzyl isothiocyanate and phenethyl isothiocyanate on benzo[a]pyrene metabolism and DNA adduct formation in the A/J mouse by Sticha, Kristina R.K., Staretz, Marianne E., Wang, Mingyao, Liang, Hong, Kenney, Patrick M.J., Hecht, Stephen S.

“…Benzyl isothiocyanate (BITC) inhibits lung tumorigenesis induced in A/J mice by benzo[a]pyrene (B[a]P). In contrast, phenethyl isothiocyanate (PEITC) does not…”
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Identification of cyanidin glycosides as constituents of freeze-dried black raspberries which inhibit anti-benzo[a]pyrene-7,8-diol-9,10-epoxide induced NFκB and AP-1 activity by Hecht, Stephen S., Huang, Chuanshu, Stoner, Gary D., Li, Jingxia, Kenney, Patrick M.J., Sturla, Shana J., Carmella, Steven G.

“…Dietary freeze-dried black raspberries inhibit tumor induction by N-nitrosomethylbenzylamine in the rat esophagus, but the constituents responsible for this…”
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Investigation of the Reaction of Myosmine with Sodium Nitrite in Vitro and in Rats by Hecht, Stephen S, Han, Shaomei, Kenney, Patrick M. J, Wang, Mingyao, Lindgren, Bruce, Wang, Yong, Lao, Yanbin, Hochalter, J. Bradley, Upadhyaya, Pramod

“…Previous studies have shown that the minor tobacco alkaloid myosmine (5) reacts with NaNO2 in the presence of acid to yield 4-hydroxy-1-(3-pyridyl)-1-butanone…”
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Identification of cyanidin glycosides as constituents of freeze-dried black raspberries which inhibit anti-benzo[a]pyrene-7,8-diol-9,10-epoxide induced NF[kappa]B and AP-1 activity by Hecht, Stephen S, Huang, Chuanshu, Stoner, Gary D, Li, Jingxia, Patrick M.J. Kenney, Sturla, Shana J, Carmella, Steven G

“…Dietary freeze-dried black raspberries inhibit tumor induction by N-nitrosomethylbenzylamine in the rat esophagus, but the constituents responsible for this…”
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Tumorigenicity and metabolism of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol enantiomers and metabolites in the A/J mouse by Upadhyaya, Pramod, Kenney, Patrick M.J., Hochalter, J. Bradley, Wang, Mingyao, Hecht, Stephen S.

“…4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanol (NNAL), a major metabolite of the tobacco-specific pulmonary carcinogen…”
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Dose–response study of myo-inositol as an inhibitor of lung tumorigenesis induced in A/J mice by benzo[ a]pyrene and 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone by Hecht, Stephen S., Kenney, Patrick M.J., Wang, Mingyao, Upadhyaya, Pramod

“…Dietary myo-inositol is an effective inhibitor of lung tumor induction in mice, but no dose–response studies have been reported. We assessed the ability of…”
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Stereospecific Deuterium Substitution Attenuates the Tumorigenicity and Metabolism of the Tobacco-Specific Nitrosamine 4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) by Jalas, John R, McIntee, Edward J, Kenney, Patrick M. J, Upadhyaya, Pramod, Peterson, Lisa A, Hecht, Stephen S

“…Stereochemical determinants of the tumorigenicity and metabolism of the tobacco-specific nitrosamine 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) were…”
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