Search Results - "Kenney, M. A"

Mitogenic Sonic hedgehog signaling drives E2F1-dependent lipogenesis in progenitor cells and medulloblastoma by Bhatia, B, Hsieh, M, Kenney, A M, Nahlé, Z

“…Deregulation of the Rb/E2F tumor suppressor complex and aberrantion of Sonic hedgehog (Shh) signaling are documented across the spectrum of human malignancies…”
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Divergent functions for eIF4E and S6 kinase by sonic hedgehog mitogenic signaling in the developing cerebellum by Mainwaring, L A, Kenney, A M

“…Cerebellar development entails rapid peri-natal proliferation of cerebellar granule neuron precursors (CGNPs), proposed cells-of-origin for certain…”
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From global change science to action with social sciences by Weaver, C. P., Mooney, S., Allen, D., Beller-Simms, N., Fish, T., Grambsch, A. E., Hohenstein, W., Jacobs, K., Kenney, M. A., Lane, M. A., Langner, L., Larson, E., McGinnis, D. L., Moss, R. H., Nichols, L. G., Nierenberg, C., Seyller, E. A., Stern, P. C., Winthrop, R.

“…US efforts to integrate social and biophysical sciences to address the issue of global change exist within a wider movement to understand global change as a…”
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Oncogenic YAP promotes radioresistance and genomic instability in medulloblastoma through IGF2-mediated Akt activation by Fernandez-L, A, Squatrito, M, Northcott, P, Awan, A, Holland, E C, Taylor, M D, Nahlé, Z, Kenney, A M

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Exploring ecological patterns with structural equation modeling and Bayesian analysis by Arhonditsis, G.B., Stow, C.A., Steinberg, L.J., Kenney, M.A., Lathrop, R.C., McBride, S.J., Reckhow, K.H.

“…Structural equation modeling is a multivariate statistical method that allows evaluation of a network of relationships between manifest and latent variables…”
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A Predictive Approach to Nutrient Criteria by Reckhow, K. H, Arhonditsis, G. B, Kenney, M. A, Hauser, L, Tribo, J, Wu, C, Elcock, K. J, Steinberg, L. J, Stow, C. A, McBride, S. J

“…Violation of a water quality standard triggers the need for a total maximum daily load (TMDL); this should result in actions that improve water quality, but…”
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Rescue of alpha -SNS Sodium Channel Expression in Small Dorsal Root Ganglion Neurons After Axotomy by Nerve Growth Factor In Vivo by Dib-Hajj, S. D, Black, J. A, Cummins, T. R, Kenney, A. M, Kocsis, J. D, Waxman, S. G

“…S. D. Dib-Hajj , J. A. Black , T. R. Cummins , A. M. Kenney , J. D. Kocsis , and S. G. Waxman Department of Neurology, Yale University School of Medicine, New…”
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Oncogenic YAP promotes radioresistance and genomic instability in medulloblastoma through IGF2-mediated Akt activation by Fernandez-L, A, Squatrito, M, Northcott, P, Awan, A, Holland, E C, Taylor, M D, Nahlé, Z, Kenney, A M

“…Radiation therapy remains the standard of care for many cancers, including the malignant pediatric brain tumor medulloblastoma. Radiation leads to long-term…”
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In vitro autoradiographic localization of amylin binding sites in rat brain by Sexton, P M, Paxinos, G, Kenney, M A, Wookey, P J, Beaumont, K

“…Amylin is a recently discovered 37 amino acid peptide which is co-secreted from the pancreas with insulin and acts to modulate carbohydrate metabolism…”
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YB-1 is elevated in medulloblastoma and drives proliferation in Sonic hedgehog-dependent cerebellar granule neuron progenitor cells and medulloblastoma cells by Dey, A, Robitaille, M, Remke, M, Maier, C, Malhotra, A, Gregorieff, A, Wrana, J L, Taylor, M D, Angers, S, Kenney, A M

“…Postnatal proliferation of cerebellar granule neuron precursors (CGNPs), proposed cells of origin for the SHH-associated subgroup of medulloblastoma, is driven…”
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High affinity amylin binding sites in rat brain by Beaumont, K, Kenney, M A, Young, A A, Rink, T J

“…Amylin, a 37-amino acid peptide structurally related to calcitonin gene-related peptide, is synthesized in and released along with insulin from pancreatic…”
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WIP1 modulates responsiveness to Sonic Hedgehog signaling in neuronal precursor cells and medulloblastoma by Wen, J, Lee, J, Malhotra, A, Nahta, R, Arnold, A R, Buss, M C, Brown, B D, Maier, C, Kenney, A M, Remke, M, Ramaswamy, V, Taylor, M D, Castellino, R C

“…High-level amplification of the protein phosphatase PPM1D ( WIP1 ) is present in a subset of medulloblastomas (MBs) that have an expression profile consistent…”
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Sonic hedgehog promotes G(1) cyclin expression and sustained cell cycle progression in mammalian neuronal precursors by Kenney, A M, Rowitch, D H

“…Sonic hedgehog (Shh) signal transduction via the G-protein-coupled receptor, Smoothened, is required for proliferation of cerebellar granule neuron precursors…”
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Effects of magnesium deficiency on strength, mass, and composition of rat femur by KENNEY, M. A, MCCOY, H, WILLIAMS, L

“…Magnesium (Mg) participates in the normal formation and remodeling of bone. However, little is known about effects of Mg status on the biomechanical function…”
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Nmyc upregulation by sonic hedgehog signaling promotes proliferation in developing cerebellar granule neuron precursors by Kenney, Anna Marie, Cole, Michael D, Rowitch, David H

“…Hedgehog pathway activation is required for expansion of specific neuronal precursor populations during development and is etiologic in the human cerebellar…”
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Iron, copper, and zinc status: response to supplementation with zinc or zinc and iron in adult females by Yadrick, M K, Kenney, M A, Winterfeldt, E A

“…Response of iron, copper, and zinc status to supplementation with Zn or a combination of Zn and Fe was assessed in adult females in a 10-wk study. Group Z…”
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Hedgehog and PI-3 kinase signaling converge on Nmyc1 to promote cell cycle progression in cerebellar neuronal precursors by Kenney, Anna Marie, Widlund, Hans R, Rowitch, David H

“…Neuronal precursor cells in the developing cerebellum require activity of the sonic hedgehog (Shh) and phosphoinositide-3-kinase (PI3K) pathways for growth and…”
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Development of mice expressing a single D-type cyclin by Ciemerych, Maria A, Kenney, Anna M, Sicinska, Ewa, Kalaszczynska, Ilona, Bronson, Roderick T, Rowitch, David H, Gardner, Humphrey, Sicinski, Piotr

“…D-cyclins (cyclins D1, D2, and D3) are components of the core cell cycle machinery. To directly test the ability of each D-cyclin to drive development of…”
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Relation of Boron to the Composition and Mechanical Properties of Bone by McCoy, Harriett, Kenney, Mary Alice, Montgomery, Catherine, Irwin, Amy, Williams, Louise, Orrell, Rhonda

“…A review of the experimental studies relating boron to biological effects on appendicular and axial bones in animal models suggests that numerous influences,…”
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Peripheral Axotomy Induces Long-Term c-Jun Amino-Terminal Kinase-1 Activation and Activator Protein-1 Binding Activity by c-Jun and junD in Adult Rat Dorsal Root Ganglia In Vivo by Kenney, Anna Marie, Kocsis, Jeffery D

“…One of the earliest documented molecular events after sciatic nerve injury in adult rats is the rapid, long-term upregulation of the immediate early gene…”
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