Search Results - "Kenney, John M"
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1
Genetic organization, length conservation, and evolution of RNA polymerase II carboxyl-terminal domain
Published in Molecular biology and evolution (01-11-2010)“…With a simple tandem iterated sequence, the carboxyl terminal domain (CTD) of eukaryotic RNA polymerase II (RNAP II) serves as the central coordinator of mRNA…”
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2
Structural Disorder in Silk Proteins Reveals the Emergence of Elastomericity
Published in Biomacromolecules (01-01-2008)“…Spider silks combine basic amino acids into strong and versatile fibers where the quality of the elastomer is attributed to the interaction of highly adapted…”
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3
Amyloidogenic nature of spider silk
Published in European journal of biochemistry (01-08-2002)“…In spiders soluble proteins are converted to form insoluble silk fibres, stronger than steel. The final fibre product has long been the subject of study;…”
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4
Zn2+-binding in the glutamate-rich region of the intrinsically disordered protein prothymosin-alpha
Published in Journal of biological inorganic chemistry (01-12-2018)“…Prothymosin-α is a small, multifunctional intrinsically disordered protein associated with cell survival and proliferation which binds multiple Zn 2+ ions and…”
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5
Conformational polymorphism, stability and aggregation in spider dragline silks proteins
Published in International journal of biological macromolecules (15-09-2005)“…Spider silk is spun in a complex and unique process, thought to depend on a hydrophobic conversion of a predominantly disordered to a β-sheet rich protein…”
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6
Spider Silk Protein Refolding Is Controlled by Changing pH
Published in Biomacromolecules (01-05-2004)“…Spidroins, the major silk proteins making up the spider's dragline silk, originate in two distinct tissue layers (A and B) in the spider's major ampullate…”
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7
The Y42H mutation in medium‐chain acyl‐CoA dehydrogenase, which is prevalent in babies identified by MS/MS‐based newborn screening, is temperature sensitive
Published in European journal of biochemistry (01-10-2004)“…Medium‐chain acyl‐CoA dehydrogenase (MCAD) is a homotetrameric flavoprotein which catalyses the initial step of the β‐oxidation of medium‐chain fatty acids…”
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8
Calorimetric investigation of copper(II) binding to Aβ peptides: thermodynamics of coordination plasticity
Published in Journal of biological inorganic chemistry (01-04-2012)“…Metal ions have been shown to play a critical role in β-amyloid (Aβ) neurotoxicity, thus prompting an intense investigation into the formation of metal–Aβ…”
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9
Evolutionary conservation in the hepatitis B virus core structure: comparison of human and duck cores
Published in Structure (London) (15-10-1995)“…Background: Hepatitis B virus is a major human pathogen which has been extensively studied, yet its structure is unknown. Cryo-electron microscopy of the viral…”
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10
Noise Characterization in Circular Dichroism Spectroscopy
Published in Applied spectroscopy (01-02-2012)“…Circular dichroism (CD), defined as the difference in absorption between left and right circularly polarized light, is used to spectroscopically study the…”
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11
Glycerin as a Renewable Feedstock for Epichlorohydrin Production. The GTE Process
Published in Clean : soil, air, water (01-08-2008)“…A significant improvement in a process to produce epichlorohydrin through the use of glycerin as renewable feedstock is presented. The glycerin to…”
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12
Transition to a β-Sheet-Rich Structure in Spidroin in Vitro: The Effects of pH and Cations
Published in Biochemistry (Easton) (09-11-2004)“…Unlike man-made fibers, the silks of spiders are spun from aqueous solutions and at atmospheric pressure in a process still poorly understood. The molecular…”
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13
Modeling, Characterizing, and Accommodating Static Birefringence in Circular and Linear Dichroism Spectroscopy
Published in Applied spectroscopy (01-10-2013)“…Nearly all circular dichroism (CD) and linear dichroism (LD) spectrometers use a photoelastic modulator (PEM) in which an optical element is stressed using a…”
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14
Novel Technique for Improvement in Calibration of the Photoelastic Modulator in Circular and Linear Dichroism Spectroscopy
Published in Applied spectroscopy (01-01-2013)“…Both the voltage-induced and the inherent (static) birefringence of a photoelastic modulator (PEM) affect the phase difference between orthogonal components of…”
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15
Respiratory adaptations in a deep-sea orbiniid polychaete from Gulf of Mexico brine pool NR-1: metabolic rates and hemoglobin structure/function relationships
Published in Journal of experimental biology (01-06-2002)“…Methanoaricia dendrobranchiata Blake (Polychaeta; Orbiniidae) occurs in large numbers in association with communities of the mussel Bathymodiolus childressi at…”
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16
Characterization of Mutations in the GTP-binding Domain of IF2 Resulting in Cold-sensitive Growth of Escherichia coli
Published in Journal of molecular biology (14-02-2003)“…The infB gene encodes translation initiation factor IF2. We have determined the entire sequence of infB from two cold-sensitive Escherichia coli strains IQ489…”
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The high concentration of Arg213-->Gly extracellular superoxide dismutase (EC-SOD) in plasma is caused by a reduction of both heparin and collagen affinities
Published in Biochemical journal (15-01-2005)“…The C-terminal region of EC-SOD (extracellular superoxide dismutase) mediates the binding to both heparin/heparan sulphate and type I collagen. A mutation…”
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18
Determination of microtubule polarity by cryo-electron microscopy
Published in Structure (London) (15-09-1996)“…Background Microtubules are tubular polymers of tubulin dimers, which are arranged head-to-tail in protofilaments that run lengthwise along the microtubules,…”
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Secondary Structures and Conformational Changes in Flagelliform, Cylindrical, Major, and Minor Ampullate Silk Proteins. Temperature and Concentration Effects
Published in Biomacromolecules (01-11-2004)“…Orb weaver spiders use exceptionally complex spinning processes to transform soluble silk proteins into solid fibers with specific functions and mechanical…”
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20
Structural Conformation of Spidroin in Solution: A Synchrotron Radiation Circular Dichroism Study
Published in Biomacromolecules (01-05-2004)“…Spider silk is made and spun in a complex process that tightly controls the conversion from soluble protein to insoluble fiber. The mechanical properties of…”
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