Search Results - "Kennette, Wendy"

Nuclear localization of maspin is essential for its inhibition of tumor growth and metastasis by Goulet, Brigitte, Kennette, Wendy, Ablack, Amber, Postenka, Carl O, Hague, M Nicole, Mymryk, Joe S, Tuck, Alan B, Giguère, Vincent, Chambers, Ann F, Lewis, John D

“…Maspin (mammary serine protease inhibitor or SerpinB5) acts as a tumor suppressor when overexpressed in aggressive cancer cell lines. However, its role in…”
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Multi-platform whole-genome microarray analyses refine the epigenetic signature of breast cancer metastasis with gene expression and copy number by Andrews, Joseph, Kennette, Wendy, Pilon, Jenna, Hodgson, Alexandra, Tuck, Alan B, Chambers, Ann F, Rodenhiser, David I

“…We have previously identified genome-wide DNA methylation changes in a cell line model of breast cancer metastasis. These complex epigenetic changes that we…”
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Epigenetic mapping and functional analysis in a breast cancer metastasis model using whole-genome promoter tiling microarrays by Rodenhiser, David I, Andrews, Joseph, Kennette, Wendy, Sadikovic, Bekim, Mendlowitz, Ariel, Tuck, Alan B, Chambers, Ann F

“…Breast cancer metastasis is a complex, multi-step biological process. Genetic mutations along with epigenetic alterations in the form of DNA methylation…”
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Metallothionein mediates the level and activity of nuclear factor kappa B in murine fibroblasts by Butcher, Heather L, Kennette, Wendy A, Collins, Olga, Zalups, Rudolfs K, Koropatnick, James

“…The zinc-binding protein metallothionein (MT) is associated with resistance to apoptosis. We examined whether MT regulates the zinc-dependent antiapoptotic…”
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Wendy Kennette

“…Wendy Kennette shares some of her experiences practicing as a palliative medicine physician through the COVID-19 pandemic and how her practice and personal…”
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Basal and Zinc-Induced Metallothionein in Resistance to Cadmium, Cisplatin, Zinc, and tertButyl Hydroperoxide: Studies Using MT Knockout and Antisense-Downregulated MT in Mammalian Cells by Kennette, Wendy, Collins, Olga M., Zalups, Rudolfs K., Koropatnick, Jim

“…Metallothioneins (MTs) mediate resistance to metal and non-metal toxicants. To differentiate the role of MTs from other protective factors, resistance to zinc…”
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Subcellular targeting of human interleukin-10 in plants by Menassa, Rima, Kennette, Wendy, Nguyen, Vi, Rymerson, Robert, Jevnikar, Anthony, Brandle, Jim

“…The utility of plants for the production of a wide range of recombinant proteins is now clearly established. However, the challenge remains to produce these…”
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Zinc-Metallothionein Levels Are Correlated with Enhanced Glucocorticoid Responsiveness in Mouse Cells Exposed to ZnCl2, HgCl2, and Heat Shock by DeMoor, Janice M., Kennette, Wendy A., Collins, Olga M., Koropatnick, James

“…Metallothioneins (MTs) are the major low molecular weight, zinc-binding proteins in mammalian cells. It has been hypothesized that they play a role in the…”
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Lymphatic metastasis of breast cancer cells is associated with differential gene expression profiles that predict cancer stem cell-like properties and the ability to survive, establish and grow in a foreign environment by PANDIT, Terlika S, KENNETTE, Wendy, CHAMBERS, Ann F, TUCK, Alan B, MACKENZIE, Lisa, GUIHUA ZHANG, AL-KATIB, Waleed, ANDREWS, Joseph, VANTYGHEM, Sharon A, ORMOND, D. George, ALLAN, Alison L, RODENHISER, David I

“…Although lymphatic dissemination is a major route for breast cancer metastasis, there has been little work to determine what factors control the ability of…”
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A sensitive time-resolved fluorescent immunoassay for metallothionein protein by Butcher, Heather, Kennette, Wendy, Collins, Olga, Demoor, Janice, Koropatnick, James

“…Metallothioneins (MTs) are a family of low molecular weight metal-binding proteins induced by a broad range of stress conditions, including exposure to…”
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