Search Results - "Kennerley, Aneurin J"

Hyperpolarising Pyruvate through Signal Amplification by Reversible Exchange (SABRE) by Iali, Wissam, Roy, Soumya S., Tickner, Ben J., Ahwal, Fadi, Kennerley, Aneurin J., Duckett, Simon B.

“…Hyperpolarisation methods that premagnetise agents such as pyruvate are currently receiving significant attention because they produce sensitivity gains that…”
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Investigation of the neurovascular coupling in positive and negative BOLD responses in human brain at 7T by Huber, Laurentius, Goense, Jozien, Kennerley, Aneurin J., Ivanov, Dimo, Krieger, Steffen N., Lepsien, Jöran, Trampel, Robert, Turner, Robert, Möller, Harald E.

“…Decreases in stimulus-dependent blood oxygenation level dependent (BOLD) signal and their underlying neurovascular origins have recently gained considerable…”
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Validating layer-specific VASO across species by Huber, Laurentius (Renzo), Poser, Benedikt A, Kaas, Amanda L, Fear, Elizabeth J, Dresbach, Sebastian, Berwick, Jason, Goebel, Rainer, Turner, Robert, Kennerley, Aneurin J

“…•Our goal is to validate layer-specific VASO fMRI with gold standard methods.•Layer-specific VASO sequences are implemented for 7T imaging in humans and…”
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Negative Blood Oxygen Level Dependence in the Rat:A Model for Investigating the Role of Suppression in Neurovascular Coupling by Boorman, Luke, Kennerley, Aneurin J, Johnston, David, Jones, Myles, Zheng, Ying, Redgrave, Peter, Berwick, Jason

“…Modern neuroimaging techniques rely on neurovascular coupling to show regions of increased brain activation. However, little is known of the neurovascular…”
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A novel automated rodent tracker (ART), demonstrated in a mouse model of amyotrophic lateral sclerosis by Hewitt, Brett M., Yap, Moi Hoon, Hodson-Tole, Emma F., Kennerley, Aneurin J., Sharp, Paul S., Grant, Robyn A.

“…•Custom-made open-source, automated rodent tracker (ART).•Tracks rodent locomotion and identifies general behaviours.•Validated against manual tracking and…”
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Optimised and rapid pre-clinical screening in the SOD1(G93A) transgenic mouse model of amyotrophic lateral sclerosis (ALS) by Mead, Richard J, Bennett, Ellen J, Kennerley, Aneurin J, Sharp, Paul, Sunyach, Claire, Kasher, Paul, Berwick, Jason, Pettmann, Brigitte, Battaglia, Guiseppe, Azzouz, Mimoun, Grierson, Andrew, Shaw, Pamela J

“…The human SOD1(G93A) transgenic mouse has been used extensively since its development in 1994 as a model for amyotrophic lateral sclerosis (ALS). In that time,…”
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23Na MRI: inter-reader reproducibility of normal fibroglandular sodium concentration measurements at 3 T by Arponen, Otso, McLean, Mary A., Nanaa, Muzna, Manavaki, Roido, Baxter, Gabrielle C., Gill, Andrew B., Riemer, Frank, Kennerley, Aneurin J., Woitek, Ramona, Kaggie, Joshua D., Brackenbury, William J., Gilbert, Fiona J.

“…Background To study the reproducibility of 23 Na magnetic resonance imaging (MRI) measurements from breast tissue in healthy volunteers. Methods Using a…”
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Physiological and Pathological Brain Activation in the Anesthetized Rat Produces Hemodynamic-Dependent Cortical Temperature Increases That Can Confound the BOLD fMRI Signal by Harris, Samuel S, Boorman, Luke W, Das, Devashish, Kennerley, Aneurin J, Sharp, Paul S, Martin, Chris, Redgrave, Peter, Schwartz, Theodore H, Berwick, Jason

“…Anesthetized rodent models are ubiquitous in pre-clinical neuroimaging studies. However, because the associated cerebral morphology and experimental…”
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Concurrent fMRI and optical measures for the investigation of the hemodynamic response function by Kennerley, Aneurin J., Berwick, Jason, Martindale, John, Johnston, David, Papadakis, Nikos, Mayhew, John E.

“…Functional magnetic resonance imaging (fMRI) signal variations are based on a combination of changes in cerebral blood flow (CBF) and volume (CBV), and blood…”
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Hyperpolarising Pyruvate through Signal Amplification by Reversible Exchange (SABRE) by Iali, Wissam, Roy, Soumya S., Tickner, Ben J., Ahwal, Fadi, Kennerley, Aneurin J., Duckett, Simon B.

“…Hyperpolarisation methods that premagnetise agents such as pyruvate are currently receiving significant attention because they produce sensitivity gains that…”
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Cortical lamina-dependent blood volume changes in human brain at 7T by Huber, Laurentius, Goense, Jozien, Kennerley, Aneurin J, Trampel, Robert, Guidi, Maria, Reimer, Enrico, Ivanov, Dimo, Neef, Nicole, Gauthier, Claudine J, Turner, Robert, Möller, Harald E

“…Cortical layer-dependent high (sub-millimeter) resolution functional magnetic resonance imaging (fMRI) in human or animal brain can be used to address…”
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Cortical lamina-dependent blood volume changes in human brain at 7 T by Huber, Laurentius, Goense, Jozien, Kennerley, Aneurin J, Trampel, Robert, Guidi, Maria, Reimer, Enrico, Ivanov, Dimo, Neef, Nicole, Gauthier, Claudine J, Turner, Robert, Möller, Harald E

“…Cortical layer-dependent high (sub-millimeter) resolution functional magnetic resonance imaging (fMRI) in human or animal brain can be used to address…”
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Directing cell therapy to anatomic target sites in vivo with magnetic resonance targeting by Muthana, Munitta, Kennerley, Aneurin J., Hughes, Russell, Fagnano, Ester, Richardson, Jay, Paul, Melanie, Murdoch, Craig, Wright, Fiona, Payne, Christopher, Lythgoe, Mark F., Farrow, Neil, Dobson, Jon, Conner, Joe, Wild, Jim M., Lewis, Claire

“…Cell-based therapy exploits modified human cells to treat diseases but its targeted application in specific tissues, particularly those lying deep in the body…”
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Real-time magnetic resonance imaging: mechanics of oral and facial function by Kennerley, Aneurin J., Mitchell, David A., Sebald, Angelika, Watson, Isaac

“…We report a summary of developmental work to explore, develop, and establish clinical applications of real-time magnetic resonance imaging (rtMRI) with a…”
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Sodium accumulation in breast cancer predicts malignancy and treatment response by James, Andrew D., Leslie, Theresa K., Kaggie, Joshua D., Wiggins, Laura, Patten, Lewis, Murphy O’Duinn, John, Langer, Swen, Labarthe, Marie-Christine, Riemer, Frank, Baxter, Gabrielle, McLean, Mary A., Gilbert, Fiona J., Kennerley, Aneurin J., Brackenbury, William J.

“…Background Breast cancer remains a leading cause of death in women and novel imaging biomarkers are urgently required. Here, we demonstrate the diagnostic and…”
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Investigation of the neurovascular coupling in positive and negative BOLD responses in human brain at 7 T by HUBER, Laurentius, GOENSE, Jozien, KENNERLEY, Aneurin J, IVANOV, Dimo, KRIEGER, Steffen N, LEPSIEN, Jöran, TRAMPEL, Robert, TURNER, Robert, MÖLLER, Harald E

“…Decreases in stimulus-dependent blood oxygenation level dependent (BOLD) signal and their underlying neurovascular origins have recently gained considerable…”
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Use of 31 P magnetisation transfer magnetic resonance spectroscopy to measure ATP changes after 670 nm transcranial photobiomodulation in older adults by Fear, Elizabeth J., Torkelsen, Frida H., Zamboni, Elisa, Chen, Kuan‐Ju, Scott, Martin, Jeffery, Glenn, Baseler, Heidi, Kennerley, Aneurin J.

“…Abstract Mitochondrial function declines with age, and many pathological processes in neurodegenerative diseases stem from this dysfunction when mitochondria…”
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SABRE hyperpolarized anticancer agents for use in 1H MRI by Fear, Elizabeth J., Kennerley, Aneurin J., Rayner, Peter J., Norcott, Philip, Roy, Soumya S., Duckett, Simon B.

“…Purpose Enabling drug tracking (distribution/specific pathways) with magnetic resonance spectroscopy requires manipulation (via hyperpolarization) of spin…”
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Real-Time High-Sensitivity Reaction Monitoring of Important Nitrogen-Cycle Synthons by 15 N Hyperpolarized Nuclear Magnetic Resonance by Rayner, Peter J, Fekete, Marianna, Gater, Callum A, Ahwal, Fadi, Turner, Norman, Kennerley, Aneurin J, Duckett, Simon B

“…Here, we show how signal amplification by reversible exchange hyperpolarization of a range of N-containing synthons can be used to enable studies of their…”
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Real-Time High-Sensitivity Reaction Monitoring of Important Nitrogen-Cycle Synthons by 15N Hyperpolarized Nuclear Magnetic Resonance by Rayner, Peter J., Fekete, Marianna, Gater, Callum A., Ahwal, Fadi, Turner, Norman, Kennerley, Aneurin J., Duckett, Simon B.

“…Here, we show how signal amplification by reversible exchange hyperpolarization of a range of 15N-containing synthons can be used to enable studies of their…”
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