Search Results - "Kennel, S.J"

Detection of cardiac amyloidosis by PET/CT imaging using 124I-p5+14 peptide by Wall, J, Martin, E.B, Stuckey, A, Richey, T, Williams, A.D, Whittle, B, Fu, Y, Powell, D, Heidel, R.E, Besozzi, M, Lands, R, Guthrie, S, Kennel, S.J

“…Abstract Introduction Systemic amyloidosis is characterized by the deposition of protein fibrils in abdominothoracic organs, notably the heart, leading to…”
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Therapy of rat tracheal carcinoma IC-12 in SCID mice by Kennel, S.J., Lankford, T., Davern, S., Foote, L., Taniguchi, K., Ohizumi, I., Tsutsumi, Y., Nakagawa, S., Mayumi, T., Mirzadeh, S.

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Thrombomodulin is preferentially expressed in Balb/c lung microvessels by FORD, V. A, STRINGER, C, KENNEL, S. J

“…Previously, two rat monoclonal antibodies where developed which bind distinct epitopes on a murine glycoprotein, P112, which is expressed primarily in lung…”
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Comparison of 225actinium chelates: tissue distribution and radiotoxicity by Davis, I.A, Glowienka, K.A, Boll, R.A, Deal, K.A, Brechbiel, M.W, Stabin, M, Bochsler, P.N, Mirzadeh, S, Kennel, S.J

“…The biodistribution and tissue toxicity of intravenously administered 225-actinium ( 225Ac) complexed with acetate, ethylene diamine tetraacetic acid (EDTA),…”
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Comparison of techniques for enzyme immobilization on silicon supports by Subramanian, Aravind, Kennel, Stephen J., Oden, Patrick I., Jacobson, K.Bruce, Woodward, Jonathan, Doktycz, Mitchel J.

“…Enzyme immobilization onto silicon substrates has been investigated by five different coupling procedures. The methods included covalent coupling either…”
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Monoclonal Antibodies in Cancer Detection and Therapy by Kennel, Stephen J., Flynn, Kathy, Foote, Linda, Lankford, Trish

“…The advent of monoclonal antibodies has revolutionized our thinking about cancer therapy management. In this article, we attempt to review some of the…”
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Direct binding of radioiodinated monoclonal antibody to tumor cells: significance of antibody purity and affinity for drug targeting or tumor imaging by Kennel, S J, Foote, L J, Lankford, P K, Johnson, M, Mitchell, T, Braslawsky, G R

“…For MoAb to be used efficiently for drug targeting and tumor imaging, the fraction of antibody binding to tumor cells must be maximized. We have studied the…”
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Lipid Composition is Important for Highly Efficient Target Binding and Retention of Immunoliposomes by Maruyama, Kazuo, Kennel, Stephen J., Huang, Leaf

“…By taking advantage of a monoclonal IgG antibody, 34A, which is highly specific to pulmonary endothelial cells, we have prepared liposomes containing various…”
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Therapy of rat tracheal carcinoma IC-12 in SCID mice: vascular targeting with [213Bi]-MAb TES-23 by Kennel, S.J., Lankford, T., Davern, S., Foote, L., Taniguchi, K., Ohizumi, I., Tsutsumi, Y., Nakagawa, S., Mayumi, T., Mirzadeh, S.

“…In previous work, we have demonstrated that vascular targeting of [213Bi], an α-emitter, to lung blood vessels could efficiently destroy tumour colonies…”
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Observations on Light-Induced Oxidation Reactions in the Electron Transport System of Chromatium by Kennel, S.J., Bartsch, R.G., Kamen, M.D.

“…Light-induced cytochrome oxidations in Chromatium subchromatophore particles were studied in detail. These reactions were found to be dependent not only on…”
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Labeling and distribution of linear peptides identified using in vivo phage display selection for tumors by Kennel, Stephen J, Mirzadeh, Saed, Hurst, Gregory B, Foote, Linda J, Lankford, Trish K, Glowienka, Kirsten A, Chappell, Lara L, Kelso, Julie R, Davern, Sandra M, Safavy, Ahmad, Brechbiel, Martin W

“…To develop targeting molecules to be used for vascular targeting of short half-lived α-emitters for radioimmunotherapy, linear peptide phage display libraries…”
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Microdistribution of specific rat monoclonal antibodies to mouse tissues and human tumor xenografts by KENNEL, S. J, FALCIONI, R, WESLEY, J. W

“…Detailed evaluations of the microdistribution of 125I-labeled monoclonal antibodies (MoAbs) to normal tissue antigens were conducted in BALB/c mice. MoAb…”
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Integrin (α6/β4) expression in human lung cancer as monitored by specific monoclonal antibodies by COSTANTINI, R. M, FALCIONI, R, BATTISTA, P, ZUPI, G, KENNEL, S. J, COLASANTE, A, VENTURO, I, GALLO CURCIO, C, SACCHI, A

“…In this study, the expression of the alpha 6/beta 4 integrin complex was analyzed in human lung carcinomas both in vitro and in vivo, using two monoclonal…”
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Combination vascular targeted and tumor targeted radioimmunotherapy by Kennel, S J, Lankford, T K, Foote, L J, Davis, I A, Boll, R A, Mirzadeh, S

“…Rat MAb 201B, which binds to murine thrombomodulin, can deliver up to 50% of the injected dose of attached radioisotopes to the lung vascular endothelium. We…”
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Monoclonal antibody covalently coupled with fatty acid. A reagent for in vitro liposome targeting by Huang, A, Huang, L, Kennel, S J

“…Monoclonal antibody to the mouse histocompatibility antigen, H-2k, was derivatized with palmitic acid using an activated ester of N-hydroxysuccinimide. About…”
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Evaluation of 225Ac for vascular targeted radioimmunotherapy of lung tumors by Kennel, S J, Chappell, L L, Dadachova, K, Brechbiel, M W, Lankford, T K, Davis, I A, Stabin, M, Mirzadeh, S

“…Several alpha particle emitting radioisotopes have been studied for use in radioimmunotherapy. Ac-225 has the potential advantages of a relatively long half…”
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Combined clinical PET/CT and microPET small animal imaging by Yap, J.T., Hall, N.C., Townsend, D.W., Wall, J.S., Solomon, A., Kabalka, J.W., Kennel, S.J., Newport, D.F., Siegel, S.B., Bailey, D., Smith, A.M., Nutt, R.E.

“…Recent advances in multi-detector CT design have enabled isotropic sub-millimeter spatial resolution. Although dedicated small animal CT scanners have been…”
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A comparative study of the biochemical properties of human and mouse recombinant O6-methylguanine-DNA methyltransferases by Roy, R, Shiota, S, Kennel, S J, Raha, R, von Wronski, M, Brent, T P, Mitra, S

“…The O6-methylguanine-DNA methyltransferase (MGMT) repairs mutagenic and carcinogenic O6-alkylguanine in DNA by accepting stoichiometrically the alkyl group…”
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Second generation monoclonal antibodies to the human integrin alpha 6 beta 4 by Kennel, S J, Epler, R G, Lankford, T K, Foote, L J, Dickas, V, Canamucio, M, Cavalierie, R, Cosimelli, M, Venturo, I, Falcioni, R

“…Second generation monoclonal antibodies to the alpha 6 beta 4 subunits of human integrins have been prepared. MAbs 450-9D, 10D, and 11A1 react at different…”
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Binding of immunoglobulin G to phospholipid vesicles by sonication by Huang, Leaf, Kennel, Stephen J.

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