Search Results - "Kennedy, Sidney H"

Cognitive Dysfunction in Major Depressive Disorder: Effects on Psychosocial Functioning and Implications for Treatment by Lam, Raymond W, Kennedy, Sidney H, McIntyre, Roger S, Khullar, Atul

“…While there is clearly an association between improvement in depressive symptoms and functioning, symptom improvement can also be dissociated from functional…”
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Resting-State Cortico-Thalamic-Striatal Connectivity Predicts Response to Dorsomedial Prefrontal rTMS in Major Depressive Disorder by SALOMONS, Tim V, DUNLOP, Katharine, KENNEDY, Sidney H, FLINT, Alastair, GERACI, Joseph, GIACOBBE, Peter, DOWNAR, Jonathan

“…Despite its high toll on society, there has been little recent improvement in treatment efficacy for major depressive disorder (MDD). The identification of…”
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The Default Mode Network in Healthy Individuals: A Systematic Review and Meta-Analysis by Mak, Lauren E, Minuzzi, Luciano, MacQueen, Glenda, Hall, Geoffrey, Kennedy, Sidney H, Milev, Roumen

“…When the brain is not engaged in goal-directed activities and at rest, there are still measureable patterns of activity. One resting-state network, the default…”
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Trajectories of Response to Dorsolateral Prefrontal rTMS in Major Depression: A THREE-D Study by Kaster, Tyler S, Downar, Jonathan, Vila-Rodriguez, Fidel, Thorpe, Kevin E, Feffer, Kfir, Noda, Yoshihiro, Giacobbe, Peter, Knyahnytska, Yuliya, Kennedy, Sidney H, Lam, Raymond W, Daskalakis, Zafiris J, Blumberger, Daniel M

“…Objective:Repetitive transcranial magnetic stimulation (rTMS) is an effective treatment for refractory major depressive disorder, yet no studies have…”
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Anhedonia and Reward-Circuit Connectivity Distinguish Nonresponders from Responders to Dorsomedial Prefrontal Repetitive Transcranial Magnetic Stimulation in Major Depression by Downar, Jonathan, Geraci, Joseph, Salomons, Tim V, Dunlop, Katharine, Wheeler, Sarah, McAndrews, Mary Pat, Bakker, Nathan, Blumberger, Daniel M, Daskalakis, Zafiris J, Kennedy, Sidney H, Flint, Alastair J, Giacobbe, Peter

“…Background Depression is a heterogeneous mental illness. Neurostimulation treatments, by targeting specific nodes within the brain’s emotion-regulation…”
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Deep Brain Stimulation for Treatment-Resistant Depression: Follow-Up After 3 to 6 Years by Kennedy, Sidney H., Giacobbe, Peter, Rizvi, Sakina J., Placenza, Franca M., Nishikawa, Yasunori, Mayberg, Helen S., Lozano, Andres M.

“…Objective:A prevalence of at least 30% for treatment-resistant depression has prompted the investigation of alternative treatment strategies. Deep brain…”
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Anhedonia in depression and schizophrenia: A transdiagnostic challenge by Lambert, Clare, Da Silva, Susana, Ceniti, Amanda K., Rizvi, Sakina J., Foussias, George, Kennedy, Sidney H.

“…Summary Background Anhedonia, as a dysregulation of the reward circuit, is present in both Major Depressive Disorder (MDD) and schizophrenia (SZ). Aims To…”
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Brain age in mood and psychotic disorders: a systematic review and meta‐analysis by Ballester, Pedro L., Romano, Maria T., Azevedo Cardoso, Taiane, Hassel, Stefanie, Strother, Stephen C., Kennedy, Sidney H., Frey, Benicio N.

“…Objective To evaluate whether accelerated brain aging occurs in individuals with mood or psychotic disorders. Methods A systematic review following PRISMA…”
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MicroRNAs 146a/b-5 and 425-3p and 24-3p are markers of antidepressant response and regulate MAPK/Wnt-system genes by Lopez, Juan Pablo, Fiori, Laura M., Cruceanu, Cristiana, Lin, Rixing, Labonte, Benoit, Cates, Hannah M., Heller, Elizabeth A., Vialou, Vincent, Ku, Stacy M., Gerald, Christophe, Han, Ming-Hu, Foster, Jane, Frey, Benicio N., Soares, Claudio N., Müller, Daniel J., Farzan, Faranak, Leri, Francesco, MacQueen, Glenda M., Feilotter, Harriet, Tyryshkin, Kathrin, Evans, Kenneth R., Giacobbe, Peter, Blier, Pierre, Lam, Raymond W., Milev, Roumen, Parikh, Sagar V., Rotzinger, Susan, Strother, Steven C., Lewis, Cathryn M., Aitchison, Katherine J., Wittenberg, Gayle M., Mechawar, Naguib, Nestler, Eric J., Uher, Rudolf, Kennedy, Sidney H., Turecki, Gustavo

“…Antidepressants (ADs) are the most common treatment for major depressive disorder (MDD). However, only ∼30% of patients experience adequate response after a…”
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rTMS of the Dorsomedial Prefrontal Cortex for Major Depression: Safety, Tolerability, Effectiveness, and Outcome Predictors for 10 Hz Versus Intermittent Theta-burst Stimulation by Bakker, Nathan, Shahab, Saba, Giacobbe, Peter, Blumberger, Daniel M, Daskalakis, Zafiris J, Kennedy, Sidney H, Downar, Jonathan

“…Abstract Background Conventional rTMS protocols for major depression commonly employ stimulation sessions lasting >30 min. However, recent studies have sought…”
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Core symptoms of major depressive disorder: relevance to diagnosis and treatment by Kennedy, Sidney H.

“…The construct of major depressive disorder makes no etiological assumptions about populations with diverse symptom clusters. "Depressed mood" and "loss of…”
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A multicenter pilot study of subcallosal cingulate area deep brain stimulation for treatment-resistant depression by Lozano, Andres M, Giacobbe, Peter, Hamani, Clement, Rizvi, Sakina J, Kennedy, Sidney H, Kolivakis, Theodore T, Debonnel, Guy, Sadikot, Abbas F, Lam, Raymond W, Howard, Andrew K, Ilcewicz-Klimek, Magda, Honey, Christopher R, Mayberg, Helen S

“…Deep brain stimulation (DBS) has been recently investigated as a treatment for major depression. One of the proposed targets for this application is the…”
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Treatment-Resistant Depression in Primary Care across Canada by Rizvi, Sakina J, Grima, Etienne, Tan, Mary, Rotzinger, Susan, Lin, Peter, McIntyre, Roger S, Kennedy, Sidney H

“…Objective: Treatment-resistant depression (TRD) represents a considerable global health concern. The goal of the InSight study was to investigate the…”
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Novel therapeutic targets in depression: Minocycline as a candidate treatment by Soczynska, Joanna K., Mansur, Rodrigo B., Brietzke, Elisa, Swardfager, Walter, Kennedy, Sidney H., Woldeyohannes, Hanna O., Powell, Alissa M., Manierka, Marena S., McIntyre, Roger S.

“…► Regional cell loss and brain atrophy in mood disorders may be a consequence of impaired neuroplasticity. ► Neuroplasticity is regulated by neurotrophic,…”
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Zebrafish models of major depressive disorders by Fonseka, Trehani M., Wen, Xiao-Yan, Foster, Jane A., Kennedy, Sidney H.

“…The zebrafish (Danio rerio) has emerged as a model species for translational research in various neuroscience areas, including depressive disorders. Because of…”
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Deep Brain Stimulation for Treatment-Resistant Depression by Mayberg, Helen S., Lozano, Andres M., Voon, Valerie, McNeely, Heather E., Seminowicz, David, Hamani, Clement, Schwalb, Jason M., Kennedy, Sidney H.

“…Treatment-resistant depression is a severely disabling disorder with no proven treatment options once multiple medications, psychotherapy, and…”
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Investigation of miR-1202, miR-135a, and miR-16 in Major Depressive Disorder and Antidepressant Response by Fiori, Laura M, Lopez, Juan Pablo, Richard-Devantoy, Stéphane, Berlim, Marcelo, Chachamovich, Eduardo, Jollant, Fabrice, Foster, Jane, Rotzinger, Susan, Kennedy, Sidney H, Turecki, Gustavo

“…Abstract Background Major depressive disorder is a debilitating illness, which is most commonly treated with antidepressant drugs. As the majority of patients…”
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GPR56/ADGRG1 is associated with response to antidepressant treatment by Belzeaux, Raoul, Gorgievski, Victor, Fiori, Laura M., Lopez, Juan Pablo, Grenier, Julien, Lin, Rixing, Nagy, Corina, Ibrahim, El Chérif, Gascon, Eduardo, Courtet, Philippe, Richard-Devantoy, Stéphane, Berlim, Marcelo, Chachamovich, Eduardo, Théroux, Jean-François, Dumas, Sylvie, Giros, Bruno, Rotzinger, Susan, Soares, Claudio N., Foster, Jane A., Mechawar, Naguib, Tall, Gregory G., Tzavara, Eleni T., Kennedy, Sidney H., Turecki, Gustavo

“…It remains unclear why many patients with depression do not respond to antidepressant treatment. In three cohorts of individuals with depression and treated…”
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Intrinsic Connectivity Networks of Glutamate-Mediated Antidepressant Response: A Neuroimaging Review by Demchenko, Ilya, Tassone, Vanessa K., Kennedy, Sidney H., Dunlop, Katharine, Bhat, Venkat

“…Conventional monoamine-based pharmacotherapy, considered the first-line treatment for major depressive disorder (MDD), has several challenges, including high…”
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A randomized sham controlled comparison of once vs twice-daily intermittent theta burst stimulation in depression: A Canadian rTMS treatment and biomarker network in depression (CARTBIND) study by Blumberger, Daniel M., Vila-Rodriguez, Fidel, Wang, Wei, Knyahnytska, Yuliya, Butterfield, Michael, Noda, Yoshihiro, Yariv, Shahak, Isserles, Moshe, Voineskos, Daphne, Ainsworth, Nicholas J., Kennedy, Sidney H., Lam, Raymond W., Daskalakis, Zafiris J., Downar, Jonathan

“…Intermittent theta burst stimulation (iTBS) is a newer form of repetitive transcranial magnetic stimulation (rTMS) for patients with treatment resistant…”
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