Search Results - "Kennedy, R."

Aging and the rise of somatic cancer-associated mutations in normal tissues by Risques, Rosa Ana, Kennedy, Scott R

“…DNA mutations are inevitable. Despite proficient DNA repair mechanisms, somatic cells accumulate mutations during development and aging, generating cells with…”
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Does My District Need a Mobile Stroke Unit? by Lees, Kennedy R

“…In their article in this issue of the Journal on emergency medical response in cases of stroke, Grotta and colleagues 1 report several positive findings for…”
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Pharmacokinetic and pharmacodynamic drug display and simulation systems in anesthesia practice by Kennedy, R Ross

“…This review explores the use of tools and displays based on pharmacokinetic and pharmacodynamic (PK/PD) modelling of drugs used in anesthesia. The primary…”
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Alteplase for Acute Ischemic Stroke in Patients Aged >80 Years: Pooled Analyses of Individual Patient Data by Bluhmki, Erich, Danays, Thierry, Biegert, Gabriele, Hacke, Werner, Lees, Kennedy R.

“…BACKGROUND/PURPOSE:Expert guidelines specify no upper age limit for alteplase for thrombolysis of acute ischemic stroke (AIS) but, until recently, European…”
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Seeing the wood for the trees: Insights into reducing inhalational agent consumption by Kennedy, R. Ross

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Detection of Atrial Fibrillation After Ischemic Stroke or Transient Ischemic Attack: A Systematic Review and Meta-Analysis by KISHORE, Amit, VAIL, Andy, MAJID, Arshad, DAWSON, Jesse, LEES, Kennedy R, TYRRELL, Pippa J, SMITH, Craig J

“…Atrial fibrillation (AF) confers a high risk of recurrent stroke, although detection methods and definitions of paroxysmal AF during screening vary. We…”
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Guidelines for Perioperative Care in Elective Colonic Surgery: Enhanced Recovery After Surgery (ERAS®) Society Recommendations by Gustafsson, U. O., Scott, M. J., Schwenk, W., Demartines, N., Roulin, D., Francis, N., McNaught, C. E., MacFie, J., Liberman, A. S., Soop, M., Hill, A., Kennedy, R. H., Lobo, D. N., Fearon, K., Ljungqvist, O.

“…Background This review aims to present a consensus for optimal perioperative care in colonic surgery and to provide graded recommendations for items for an…”
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Carbon Dioxide Absorption During Inhalation Anesthesia: A Modern Practice by Feldman, Jeffrey M., Hendrickx, Jan, Kennedy, R. Ross

“…CO 2 absorbents were introduced into anesthesia practice in 1924 and are essential when using a circle system to minimize waste by reducing fresh gas flow to…”
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Guidelines for perioperative care in elective colonic surgery: Enhanced Recovery After Surgery (ERAS® ) Society recommendations by Gustafsson, U.O, Scott, M.J, Schwenk, W, Demartines, N, Roulin, D, Francis, N, McNaught, C.E, MacFie, J, Liberman, A.S, Soop, M, Hill, A, Kennedy, R.H, Lobo, D.N, Fearon, K, Ljungqvist, O

“…Summary Background This review aims to present a consensus for optimal perioperative care in colonic surgery and to provide graded recommendations for items…”
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Personalized vaccinology: A review by Poland, G.A., Ovsyannikova, I.G., Kennedy, R.B.

“…At the current time, the field of vaccinology remains empirical in many respects. Vaccine development, vaccine immunogenicity, and vaccine efficacy have, for…”
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Enhanced Recovery After Surgery (ERAS) for gastrointestinal surgery, part 2: consensus statement for anaesthesia practice by Feldheiser, A., Aziz, O., Baldini, G., Cox, B. P. B. W., Fearon, K. C. H., Feldman, L. S., Gan, T. J., Kennedy, R. H., Ljungqvist, O., Lobo, D. N., Miller, T., Radtke, F. F., Ruiz Garces, T., Schricker, T., Scott, M. J., Thacker, J. K., Ytrebø, L. M., Carli, F.

“…Background The present interdisciplinary consensus review proposes clinical considerations and recommendations for anaesthetic practice in patients undergoing…”
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Competing through service innovation: The role of bricolage and entrepreneurship in project-oriented firms by Salunke, Sandeep, Weerawardena, Jay, McColl-Kennedy, Janet R.

“…The criticality of service innovation in building and sustaining competitive advantage is gaining increasing recognition in the marketplace. Using empirical…”
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Endovascular stent thrombectomy: the new standard of care for large vessel ischaemic stroke by Campbell, Bruce C V, Dr, Donnan, Geoffrey A, Prof, Lees, Kennedy R, Prof, Hacke, Werner, Prof, Khatri, Pooja, Prof, Hill, Michael D, Prof, Goyal, Mayank, Prof, Mitchell, Peter J, MBBS, Saver, Jeffrey L, Prof, Diener, Hans-Christoph, Prof, Davis, Stephen M, Prof

“…Summary Background Results of initial randomised trials of endovascular treatment for ischaemic stroke, published in 2013, were neutral but limited by the…”
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Drug Titration Paradox: Comment by Sarraf, Elie, Kennedy, R Ross, Mandel, Jeff E

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Hepatitis E virus in blood components: a prevalence and transmission study in southeast England by Hewitt, Patricia E, FRCPath, Ijaz, Samreen, PhD, Brailsford, Su R, PhD, Brett, Rachel, BSc, Dicks, Steven, MSc, Haywood, Becky, BSc, Kennedy, Iain T R, MFPH, Kitchen, Alan, PhD, Patel, Poorvi, MSc, Poh, John, PhD, Russell, Katherine, MFPH, Tettmar, Kate I, MBA, Tossell, Joanne, RN, Ushiro-Lumb, Ines, FRCPath, Tedder, Richard S, Prof

“…Summary Background The prevalence of hepatitis E virus (HEV) genotype 3 infections in the English population (including blood donors) is unknown, but is…”
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Oxidative Addition of Aryl Electrophiles to a Prototypical Nickel(0) Complex: Mechanism and Structure/Reactivity Relationships by Bajo, Sonia, Laidlaw, Gillian, Kennedy, Alan R, Sproules, Stephen, Nelson, David J

“…Detailed kinetic studies of the reaction of a model Ni0 complex with a range of aryl electrophiles have been conducted. The reactions proceed via a fast ligand…”
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Detection of ultra-rare mutations by next-generation sequencing by Schmitt, Michael W, Kennedy, Scott R, Salk, Jesse J, Fox, Edward J, Hiatt, Joseph B, Loeb, Lawrence A

“…Next-generation DNA sequencing promises to revolutionize clinical medicine and basic research. However, while this technology has the capacity to generate…”
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Influence of body composition profile on outcomes following colorectal cancer surgery by Malietzis, G., Currie, A. C., Athanasiou, T., Johns, N., Anyamene, N., Glynne-Jones, R., Kennedy, R. H., Fearon, K. C. H., Jenkins, J. T.

“…Background Muscle depletion is characterized by reduced muscle mass (myopenia), and increased infiltration by intermuscular and intramuscular fat…”
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Reliability of the Modified Rankin Scale: A Systematic Review by QUINN, Terence J, DAWSON, Jesse, WALTERS, Matthew R, LEES, Kennedy R

“…A perceived weakness of the modified Rankin Scale is potential for interobserver variability. We undertook a systematic review of modified Rankin Scale…”
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Biological effects of space radiation and development of effective countermeasures by Kennedy, Ann R.

“…As part of a program to assess the adverse biological effects expected from astronauts' exposure to space radiation, numerous different biological effects…”
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