Search Results - "Kennedy, Matthew A"

ABCG1 has a critical role in mediating cholesterol efflux to HDL and preventing cellular lipid accumulation by Kennedy, Matthew A., Barrera, Gabriel C., Nakamura, Kotoka, Baldán, Ángel, Tarr, Paul, Fishbein, Michael C., Frank, Joy, Francone, Omar L., Edwards, Peter A.

“…Here we demonstrate that the ABC transporter ABCG1 plays a critical role in lipid homeostasis by controlling both tissue lipid levels and the efflux of…”
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Expression and Regulation of Multiple Murine ATP-binding Cassette Transporter G1 mRNAs/Isoforms That Stimulate Cellular Cholesterol Efflux to High Density Lipoprotein by Nakamura, Kotoka, Kennedy, Matthew A, Baldán, Angel, Bojanic, Dragana D, Lyons, Karen, Edwards, Peter A

“…The murine Abcg1 gene is reported to consist of 15 exons that encode a single mRNA (herein referred to as Abcg1-a) and protein. We now demonstrate that (i) the…”
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LXRs;: Oxysterol-activated nuclear receptors that regulate genes controlling lipid homeostasis by Edwards, Peter A, Kennedy, Matthew A, Mak, Puiying A

“…The Liver X Receptors (LXRα, NR1H3; LXRβ, NR1H2) encode highly homologous transcription factors that are members of the nuclear receptor superfamily of…”
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Positive and negative regulation of squalene synthase ( ERG9), an ergosterol biosynthetic gene, in Saccharomyces cerevisiae by Kennedy, Matthew A, Bard, Martin

“…To identify regulatory cis-elements in the proximal promoter of the yeast ERG9 squalene synthase gene, promoter deletion analysis was performed. This approach…”
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Transcriptional regulation of the squalene synthase gene ( ERG9) in the yeast Saccharomyces cerevisiae by Kennedy, Matthew A, Barbuch, Robert, Bard, Martin

“…The ergosterol biosynthetic pathway is a specific branch of the mevalonate pathway. Since the cells requirement for sterols is greater than for isoprenoids,…”
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Binding of the AVR4 elicitor of Cladosporium fulvum to chitotriose units is facilitated by positive allosteric protein-protein interactions: the chitin-binding site of AVR4 represents a novel binding site on the folding scaffold shared between the invertebrate and the plant chitin-binding domain by van den Burg, Harrold A, Spronk, Christian A E M, Boeren, Sjef, Kennedy, Matthew A, Vissers, Johannes P C, Vuister, Geerten W, de Wit, Pierre J G M, Vervoort, Jacques

“…The attack of fungal cell walls by plant chitinases is an important plant defense response to fungal infection. Anti-fungal activity of plant chitinases is…”
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Binding of the AVR4 Elicitor of Cladosporium fulvum to Chitotriose Units Is Facilitated by Positive Allosteric Protein-Protein Interactions by van den Burg, Harrold A., Spronk, Christian A.E.M., Boeren, Sjef, Kennedy, Matthew A., Vissers, Johannes P.C., Vuister, Geerten W., de Wit, Pierre J.G.M., Vervoort, Jacques

“…The attack of fungal cell walls by plant chitinases is an important plant defense response to fungal infection. Anti-fungal activity of plant chitinases is…”
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Characterization of the Human ABCG1 Gene by Kennedy, Matthew A., Venkateswaran, Asha, Tarr, Paul T., Xenarios, Ioannis, Kudoh, Jun, Shimizu, Nobuyoshi, Edwards, Peter A.

“…The human ABCG1 gene encodes a member of the ATP-binding cassette (ABC) superfamily of transporter proteins and is highly induced when macrophages are…”
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Cloning and sequencing of the Candida albicans C-4 sterol methyl oxidase gene (ERG25) and expression of an ERG25 conditional lethal mutation in Saccharomyces cerevisiae by Kennedy, M.A, Johnson, T.A, Lees, N.D, Barbuch, R, Eckstein, J.A, Bard, M

“…The ERG25 gene encoding the Candida albicans C‐4 sterol methyl oxidase was cloned and sequenced by complementing a Saccharomyces cerevisiae erg25 mutant with a…”
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Mechanism of SOS Mutagenesis of UV-Irradiated DNA: Mostly Error-Free Processing of Deaminated Cytosine by Tessman, Irwin, Liu, Shi-Kau, Kennedy, Matthew A.

“…We measured the kinetics of growth and mutagenesis of UV-irradiated DNA of phages S13 and λ that were undergoing SOS repair; the kinetics strongly suggest that…”
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Unusual kinetics of uracil formation in single and double-stranded DNA by deamination of cytosine in cyclobutane pyrimidine dimers by Tessman, I, Kennedy, M A, Liu, S K

“…Mutagenesis studies have indicated that the deamination of cytosine in UV-induced cyclobutane pyrimidine dimers is a key part of an error-free process that can…”
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Characterization of the human ABCG1 gene: liver X receptor activates an internal promoter that produces a novel transcript encoding an alternative form of the protein by Kennedy, M A, Venkateswaran, A, Tarr, P T, Xenarios, I, Kudoh, J, Shimizu, N, Edwards, P A

“…The human ABCG1 gene encodes a member of the ATP-binding cassette (ABC) superfamily of transporter proteins and is highly induced when macrophages are…”
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LXRs by Edwards, Peter A, Kennedy, Matthew A, Mak, Puiying A

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LXRs; Oxysterol-activated nuclear receptors that regulate genes controlling lipid homeostasis: Oxidized lipids as potential mediators of atheriosclerosis by EDWARDS, Peter A, KENNEDY, Matthew A, MAK, Puiying A

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Characterization of the human ABCG1 gene. Liver X receptor activates an internal promoter that produces a novel transcript encoding an alternative form of the protein by Kennedy, Matthew A., Venkateswaran, Asha, Tarr, Paul T., Xenarios, Ioannis, Kudoh, Jun, Shimizu, Nobuyoshi, Edwards, Peter A.

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DNA Polymerase II of Escherichia coli in the Bypass of Abasic Sites in Vivo by Tessman, I, Kennedy, M. A

“…The function of DNA polymerase II of Escherichia coli is an old question. Any phenotypic character that Pol II may confer upon the cell has escaped detection…”
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The two-step model of UV mutagenesis reassessed: deamination of cytosine in cyclobutane dimers as the likely source of the mutations associated with photoreactivation by Tessman, I, Kennedy, M A

“…A large increase in the incidence of bacteriophage mutants is found after photoreactivation of UV-irradiated phage S13. The increase was seen only when the…”
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